Výsledky vyhledávání - "Tadashi MIYAZAWA"

Chemistry, Properties, and in Vitro and in Vivo Applications of 2′-O-Methoxyethyl-4′-thioRNA, a Novel Hybrid Type of Chemically Modified RNA

Autor: Tatsuhiro Ishida, Mayumi Takahashi, Yota Saito, Tadashi Miyazawa, Naoshi Yamazaki, Kazuhiro Furukawa, Noriko Tarashima, Noriaki Minakawa, Mai Arai, Yosuke Hashimoto, Akira Matsuda, Kazuya Miki

Publikováno v: ChemBioChem. 15:2535-2540

We report the synthesis, properties, and in vitro and in vivo applications of 2'-O-methoxyethyl-4'-thioRNA (MOE-SRNA), a novel type of hybrid chemically modified RNA. In its hybridization with complementary RNA, MOE-SRNA showed a moderate improvement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8daa8e8afa91640a9ef531bdadf00dd
https://doi.org/10.1002/cbic.201402398

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Development of a New Dumbbell-Shaped Decoy DNA Using a Combination of the Unnatural Base Pair ImON:NaNO and a CuAAC Reaction

Autor: Noriaki Minakawa, Tadashi Miyazawa, Kazuhiro Furukawa, Yosuke Higuchi

Publikováno v: Bioconjugate Chemistry. 25:1360-1369

We describe the synthesis and potential application of a new dumbbell-shaped decoy DNA prepared using a combination of the base pair ImO(N):NaN(O) and a copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction. The CuAAC reaction between the azid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4618f89f9701ecc953b6869aa70fcbc6
https://doi.org/10.1021/bc500225r

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An epidemiological study of the effects of statin use on airflow limitation in patients with chronic obstructive pulmonary disease

Autor: Masashi Bando, Toshio Owada, Hideki Shinohara, Michiyuki Terakado, Yukihiko Sugiyama, Tadashi Miyazawa

Publikováno v: Respirology. 17:493-498

Background and objective: Chronic obstructive pulmonary disease (COPD) is considered to be a systemic inflammatory disease, and systemic inflammation has been noted as a factor contributing to cardiovascular disease, which is one of the comorbidities

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06796afbc546945652708bf7967f66c9
https://doi.org/10.1111/j.1440-1843.2011.02116.x

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[The current problems and topics regarding pulmonary function tests]

Autor: Tadashi, Miyazawa

Publikováno v: Rinsho byori. The Japanese journal of clinical pathology. 61(11)

Although the respiratory function test has a long history, the standardization of technical procedures and evaluation methods is still underway. Technologists have to be familiar not only with such standardized methods but also with quality control.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f37f395496c99c290ccf2a9cd6eef250
https://pubmed.ncbi.nlm.nih.gov/24450112

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Direct Analysis of Methamphetamine and Amphatamine Enantiomers in Human Urine by Semi-microcolumn HPLC/Electrospray Ionization Mass Spectrometry

Autor: Michiaki Tatsuno, Mayumi Nishikawa, Munehiro Katagi, Hitoshi Tsuchihashi, Tadashi Miyazawa, Ayako Suzuki, Osamu Shirota

Publikováno v: Eisei kagaku. 44:107-115

Semi-microcolumn high performance liquid chromatography (HPLC) with a columnswitching system was connected to electrospray ionization mass spectrometry (ESI-MS) for the analysis of methamphetamine (MA) and amphetamine (AP), a main metabolite of MA. U

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ffb985ec6215f035ececa243e0ad86ab
https://doi.org/10.1248/jhs1956.44.107

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Synthesis of a novel 1,2-dithianenucleoside via Pummerer-like reaction, followed by Vorbruggen glycosylation between a 1,2-dithiane derivative and uracil

Autor: Tadashi Miyazawa, Kazuhiro Furukawa, Noriko Tarashima, Takashi Ooi, Noriaki Minakawa, Kouhei Umezaki

Publikováno v: Chemical communications (Cambridge, England). 49(71)

The novel 1,2-dithianenucleoside was designed as a hybrid type of modification between 4′-thioribonucleoside and altritol nucleoside. The desired compound, i.e., 1-[(3R,4R,5S,6R)-4,5-dihydroxy-6-hydroxymethyl-1,2-dithianyl]uracil (20), was prepared

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14705e37965806b6f63e441cb0f3d330
https://pubmed.ncbi.nlm.nih.gov/23892645

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