Zobrazeno 1 - 10
of 642
pro vyhledávání: '"Tadashi KONDO"'
Autor:
Katsutoshi Kawano, Masayuki Nishi, Hideharu Kuwahara, Sho Kakizawa, Toru Inoue, Tadashi Kondo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Seismological observations indicate the presence of chemical heterogeneities at the lowermost mantle, just above the core–mantle boundary (CMB), sparking debate over their origins. A plausible explanation for the enigmatic seismic wave vel
Externí odkaz:
https://doaj.org/article/e9ad3fb9df294015b1864ac710e0e87b
Autor:
Kyra Parker, Yanfeng Zhang, Gavin Anchondo, Ashlyn Smith, Sergio Guerrero Pacheco, Tadashi Kondo, Le Su
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The SS18-SSX fusion protein is an oncogenic driver in synovial sarcoma. At the molecular level, SS18-SSX functions as both an activator and a repressor to coordinate transcription of different genes responsible for tumorigenesis. Here, we identify th
Externí odkaz:
https://doaj.org/article/3649b9f35f3b4e67807c6c0cb07b8882
Autor:
Masayuki Nishi, Si Jin, Katsutoshi Kawano, Hideharu Kuwahara, Akihiro Yamada, Shogo Kawaguchi, Yuki Mori, Tatsuhiro Sakaiya, Tadashi Kondo
Publikováno v:
Progress in Earth and Planetary Science, Vol 10, Iss 1, Pp 1-9 (2023)
Abstract Bridgmanite formation and amorphization in shocked meteorites constrain the pressure and temperature conditions during planetary impact. However, the effect of the bridgmanite grain size on its amorphization kinetics is still unclear. Here,
Externí odkaz:
https://doaj.org/article/0566de03105546e1af9d775a71c34267
Autor:
Sho Isoyama, Naomi Tamaki, Yutaka Noguchi, Mutsumi Okamura, Yuki Yoshimatsu, Tadashi Kondo, Takeshi Suzuki, Shin-ichi Yaguchi, Shingo Dan
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-10 (2023)
Abstract Translocation-related sarcomas (TRSs) harbor an oncogenic fusion gene generated by chromosome translocation and account for approximately one-third of all sarcomas; however, effective targeted therapies have yet to be established. We previou
Externí odkaz:
https://doaj.org/article/449aec3bd3674ec2a73c663ca55309a8
Autor:
Haruka Ono, Kosuke Kurosawa, Takafumi Niihara, Takashi Mikouchi, Naotaka Tomioka, Junko Isa, Hiroyuki Kagi, Takuya Matsuzaki, Hiroshi Sakuma, Hidenori Genda, Tatsuhiro Sakaiya, Tadashi Kondo, Masahiro Kayama, Mizuho Koike, Yuji Sano, Masafumi Murayama, Wataru Satake, Takafumi Matsui
Publikováno v:
Geophysical Research Letters, Vol 50, Iss 1, Pp n/a-n/a (2023)
Abstract Basaltic rocks occur widely on the terrestrial planets and differentiated asteroids, including the asteroid 4 Vesta. We conducted a shock recovery experiment with decaying compressive pulses on a terrestrial basalt at the Chiba Institute of
Externí odkaz:
https://doaj.org/article/f6350cc1eb2d493e80a4083a4c6dc48d
Publikováno v:
BMC Surgery, Vol 21, Iss 1, Pp 1-5 (2021)
Abstract Background Acute colonic pseudo-obstruction (ACPO) is a rare condition observed in patients with some underlying medical or surgical conditions. To the best of our knowledge, this is the first case report of a patient with ACPO development a
Externí odkaz:
https://doaj.org/article/5b75384baa4141ce91beb9f5baa4463f
Autor:
Tatsuya Ozawa, Syuzo Kaneko, Frank Szulzewsky, Zhiwei Qiao, Mutsumi Takadera, Yoshitaka Narita, Tadashi Kondo, Eric C. Holland, Ryuji Hamamoto, Koichi Ichimura
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-21 (2021)
Abstract Recurrent C11orf95-RELA fusions (RELA FUS ) are the hallmark of supratentorial ependymomas. The presence of RELA as the fusion partner indicates a close association of aberrant NF-κB activity with tumorigenesis. However, the oncogenic role
Externí odkaz:
https://doaj.org/article/4d9ac2956be145ce8ebb84a4126ac527
Publikováno v:
JCI Insight, Vol 7, Iss 6 (2022)
CIC-DUX4 rearrangements define an aggressive and chemotherapy-insensitive subset of undifferentiated sarcomas. The CIC-DUX4 fusion drives oncogenesis through direct transcriptional upregulation of cell cycle and DNA replication genes. Notably, CIC-DU
Externí odkaz:
https://doaj.org/article/5dc73dadcaad4c37b2a6d4c8be142289
Autor:
Mami Yasukawa, Yoshinari Ando, Taro Yamashita, Yoko Matsuda, Shisako Shoji, Masaki Suimye Morioka, Hideya Kawaji, Kumiko Shiozawa, Mitsuhiro Machitani, Takaya Abe, Shinji Yamada, Mika K. Kaneko, Yukinari Kato, Yasuhide Furuta, Tadashi Kondo, Mikako Shirouzu, Yoshihide Hayashizaki, Shuichi Kaneko, Kenkichi Masutomi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Regulated telomerase reverse transcriptase (hTERT) activity is common in human tumors. Here, the authors show that hTERT is phosphorylated by CDK1 and that this event is necessary for hTERT-mediated RNA dependent RNA polymerase activity but not for r
Externí odkaz:
https://doaj.org/article/761b43ac125a4eb99158e2f0b22fb7cd
Autor:
Rieko Oyama, Fusako Kito, Mami Takahashi, Emi Hattori, Rei Noguchi, Yoko Takai, Marimu Sakumoto, Zhiwei Qiao, Shunichi Toki, Masato Sugawara, Yoshikazu Tanzawa, Eisuke Kobayashi, Fumihiko Nakatani, Shintaro Iwata, Akihiko Yoshida, Akira Kawai, Tadashi Kondo
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background Malignant peripheral nerve sheath tumors (MPNSTs) are a rare subtype of soft-tissue sarcoma, derived from a peripheral branch or the sheath of the sciatic nerve, brachial plexus, or sacral plexus. The clinical outcomes for MPNST p
Externí odkaz:
https://doaj.org/article/d1f5d633b68e4e27ad67c4a56f2c9c08