Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Tadashi Iso"'
Autor:
Atsutoshi Ota, Masanobu Fujita, Koji Yamamoto, Junichi Iwao, Yoichi Kawashima, Tadashi Iso, Susumu Ito
Publikováno v:
Chemical and Pharmaceutical Bulletin. 38:936-941
SA2572 ((+)-1), 3-acetyl-2-[5-methoxy-2-[4-[N-methyl-N-(3,4,5-trimethoxyphenethyl) amino] butoxy]phenyl]-benzothiazoline hydrochloride is a newly synthesized Ca2+ antagonist having a inhibitory effect on the fast Na+ inward channel. In order to clari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b90d1a6043686ddd53d54b9f84ec21
https://doi.org/10.1248/cpb.38.936
https://doi.org/10.1248/cpb.38.936
Autor:
Naruhiro Ishida, Tadashi Iso, Masaaki Kageyama, Toyokazu Takada, Kiyoshi Matsuno, Hideyasu Yamauchi, Nobuaki Miyawaki
Publikováno v:
Journal of cardiovascular pharmacology. 18(6)
The antihypertensive effect of SD-3211, a structurally novel type of nondihydropyridine calcium antagonist, was assessed using several types of experimental hypertensive rats. Oral administration of SD-3211 (10, 20, and 30 mg/kg) to conscious spontan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66158a8fa43a9661e5888bb5ad6c4019
https://pubmed.ncbi.nlm.nih.gov/1725898
https://pubmed.ncbi.nlm.nih.gov/1725898
Publikováno v:
Life sciences. 48(20)
The cardiovascular effects of SD-3211, a novel benzothiazine Ca++ channel blocker, were compared with those of diltiazem and nicardipine in Langendorff-perfused rabbit hearts. SD-3211 was more potent in increasing coronary artery flow than in depress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaaa7608a73813e9c68ba9cb113b4985
https://pubmed.ncbi.nlm.nih.gov/2023522
https://pubmed.ncbi.nlm.nih.gov/2023522
Publikováno v:
Journal of cardiovascular pharmacology. 16(5)
The cardiac effects of SD-3211, a novel non-dihydropyridine type of Ca2+ antagonist, were examined in isolated guinea pig and rabbit hearts using an electrophysiological technique. SD-3211 (10(-6)-10(-5) M) shortened the action potential duration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5875f19bd9a7058bbf0e14099bc1330c
https://pubmed.ncbi.nlm.nih.gov/1703599
https://pubmed.ncbi.nlm.nih.gov/1703599
Autor:
Takafumi Koyama, Hiroyuki Yamamoto, Manabu Matsumoto, Jun Isogai, Tadashi Isomura, Shinji Tanaka
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Löffler's endocarditis (cardiac involvement in hypereosinophilic syndrome) is rare yet life-threatening if left untreated. We describe a case of hypereosinophilic syndrome presenting as a cardiac mass with an abnormal electrocardiogram. Diagnostic s
Externí odkaz:
https://doaj.org/article/89931304a6f44e5f8f73db855726cc7b
Autor:
Yuichi Notomi, MD, Tadashi Isomura, MD, Shunichi Kanai, RDCS, Masami Maeda, RN, Joji Hoshino, MD, Taichi Kondo, MD, Yasuhisa Fukada, MD, Koji Furukawa, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 4, Pp 193-202 (2016)
The selection of appropriate candidates for mitral surgery among symptomatic patients with nonischemic, chronic, secondary severe mitral regurgitation (NICSMR) remains a clinical challenge. We studied 50 consecutive symptomatic NICSMR patients for a
Externí odkaz:
https://doaj.org/article/9d4d1b441e0b4997be1457ca00f3f337
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 233:123-130
A simplified method for an angiotensin-converting enzyme activity assay in biological samples was developed. Samples were incubated with hippurylhistidylleucine, an artificial substrate of angiotensin-converting enzyme. The reaction was terminated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6783131869c3397fae50e2edbfb6dad3
https://doi.org/10.1016/s0378-4347(00)81738-7
https://doi.org/10.1016/s0378-4347(00)81738-7
Publikováno v:
Chemical and Pharmaceutical Bulletin. 34:486-495
Conversion des alcanethiols, arenethiols, cysteine, thiamine en les disulfures correspondants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::614318886658e72d7e4c2cfc6b779007
https://doi.org/10.1248/cpb.34.486
https://doi.org/10.1248/cpb.34.486
OCULAR ANTI-INFLAMMATORY AND SYSTEMIC IMMUNOSUPPRESSIVE EFFECTS OF TOPICALLY APPLIED FLUOROMETHOLONE
Publikováno v:
Japanese Journal of Pharmacology. 29:87-92
Anti-inflammatory and systemic immunosuppressive effects of topically applied steroidal and nonsteroidal anti-inflammatory agents on experimental immunogenic uveitiis in rabbits were studied. The onset of the immunogenic uveitis induced by a single i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da26ffd59c366c728a2da1dd3b49272a
https://doi.org/10.1254/jjp.29.87
https://doi.org/10.1254/jjp.29.87
Autor:
Tadashi Iso, Terumichi Iwatani, Katsuhiko Nakata, Hirokazu Kito, Hideyasu Yamauchi, Masato Horiuchi
Publikováno v:
Japanese Journal of Pharmacology. 40:367-372
A marked species difference was observed both in vitro and in vivo in the activity of SA446, an orally active inhibitor of angiotensin converting enzyme (ACE), as compared with that of captopril in five different animal species. The activity of SA446
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb3c071db3a7bc0de4502cb36991f2c
https://doi.org/10.1254/jjp.40.367
https://doi.org/10.1254/jjp.40.367