Zobrazeno 1 - 10
of 378
pro vyhledávání: '"Tadashi, Watabe"'
Autor:
Sadahiro Naka, Kazuhiro Ooe, Yoshifumi Shirakami, Kenta Kurimoto, Toshihiro Sakai, Kazuhiro Takahashi, Atsushi Toyoshima, Yang Wang, Hiromitsu Haba, Hiroki Kato, Noriyuki Tomiyama, Tadashi Watabe
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Background The alpha emitter astatine-211 (211At) is garnering attention as a novel targeted alpha therapy for patients with refractory thyroid cancer resistant to conventional therapy using beta emitter radioiodine (131I). Herein, we aimed
Externí odkaz:
https://doaj.org/article/bd01fd012682447aa829e33c3d3df674
Autor:
Daiki Nishigaki, Yuki Suzuki, Tadashi Watabe, Daisuke Katayama, Hiroki Kato, Tomohiro Wataya, Kosuke Kita, Junya Sato, Noriyuki Tomiyama, Shoji Kido
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) is widely used for the detection, diagnosis, and clinical decision-making in oncological diseases. However, in daily medical practice, it is
Externí odkaz:
https://doaj.org/article/1fb7ffeb3b2d4c37b0c6dd47935d2abe
Autor:
Mitsuaki Tatsumi, Hidenori Tanaka, Yukinori Takenaka, Motoyuki Suzuki, Takahito Fukusumi, Hirotaka Eguchi, Tadashi Watabe, Hiroki Kato, Shinichi Yachida, Hidenori Inohara, Noriyuki Tomiyama
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Circulating tumor DNA (ctDNA), which circulates in the blood after being shed from cancer cells in the body, has recently gained attention as an excellent tumor marker. The purpose of this study was to evaluate whether ct human papillomaviru
Externí odkaz:
https://doaj.org/article/17a65aea978d40d085a0a1178d2594de
Autor:
Yuta Kaizuka, Hiroyuki Suzuki, Tadashi Watabe, Kazuhiro Ooe, Atsushi Toyoshima, Kazuhiro Takahashi, Koichi Sawada, Takashi Iimori, Yoshitada Masuda, Takashi Uno, Kento Kannaka, Tomoya Uehara
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Background L-type amino acid transporter 1 (LAT1) is overexpressed in various cancers; therefore, radiohalogen-labeled amino acid derivatives targeting LAT1 have emerged as promising candidates for cancer radiotheranostics. However, 211At-la
Externí odkaz:
https://doaj.org/article/07878871b6bf4e6e88aaff2b19c3e58a
Autor:
Tadashi Watabe, Kazuko Kaneda-Nakashima, Yuichiro Kadonaga, Kazuhiro Ooe, Thosapol Sampunta, Naoki Hirose, Xiaojie Yin, Hiromitsu Haba, Yukiyoshi Kon, Atsushi Toyoshima, Jens Cardinale, Frederik L. Giesel, Koichi Fukase, Noriyuki Tomiyama, Yoshifumi Shirakami
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5667 (2024)
Astatine (211At) is a cyclotron-produced alpha emitter with a physical half-life of 7.2 h. In our previous study, the 211At-labeled prostate-specific membrane antigen (PSMA) compound ([211At]PSMA-5) exhibited excellent tumor growth suppression in a x
Externí odkaz:
https://doaj.org/article/4151f8d8ecfc4de19b8c8413cd64efb3
Autor:
Takahito Fujimori, Yuki Suzuki, Shota Takenaka, Kosuke Kita, Yuya Kanie, Takashi Kaito, Yuichiro Ukon, Tadashi Watabe, Nozomu Nakajima, Shoji Kido, Seiji Okada
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Cervical sagittal alignment is an essential parameter for the evaluation of spine disorders. Manual measurement is time-consuming and burdensome to measurers. Artificial intelligence (AI) in the form of convolutional neural networks has begu
Externí odkaz:
https://doaj.org/article/e4e2f51a27d14d598bead2f899fed52f
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
In the treatment of cancer, understanding the disease status, or accurate staging, is extremely important, and various imaging techniques are used. Computed tomography (CT), magnetic resonance imaging, and scintigrams are commonly used for solid tumo
Externí odkaz:
https://doaj.org/article/b717b9d8a125489badcea57a9d0783aa
Autor:
Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Tadashi Watabe, Kazuhiro Ooe, Xiaojie Yin, Hiromitsu Haba, Kenji Shirasaki, Hidetoshi Kikunaga, Kazuaki Tsukada, Atsushi Toyoshima, Jens Cardinale, Frederik L. Giesel, Koichi Fukase
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 933 (2024)
Currently, targeted alpha therapy (TAT) is a new therapy involving the administration of a therapeutic drug that combines a substance of α-emitting nuclides that kill cancer cells and a drug that selectively accumulates in cancer cells. It is known
Externí odkaz:
https://doaj.org/article/12ffcadf3abf4a4db03c5a48629c9d77
Autor:
Atsushi Yagishita, Miho Katsuragawa, Shin’ichiro Takeda, Yoshifumi Shirakami, Kazuhiro Ooe, Atsushi Toyoshima, Tadayuki Takahashi, Tadashi Watabe
Publikováno v:
Bioengineering, Vol 11, Iss 1, p 25 (2023)
In targeted radionuclide therapy, determining the absorbed dose of the ligand distributed to the whole body is vital due to its direct influence on therapeutic and adverse effects. However, many targeted alpha therapy drugs present challenges for in
Externí odkaz:
https://doaj.org/article/0073714b2049437aa863a030d6c35742
Autor:
Takashi Kanou, Soichiro Funaki, Masato Minami, Naoko Ose, Toru Kimura, Eriko Fukui, Tadashi Watabe, Yasushi Shintani
Publikováno v:
Thoracic Cancer, Vol 13, Iss 11, Pp 1651-1656 (2022)
Abstract Background It is often difficult to distinguish between thymoma and thymic carcinoma by preoperative radiological tests. While there have been some reports that the maximum standardized uptake value (SUVmax) in positron emission tomography
Externí odkaz:
https://doaj.org/article/9c2762401c944b199854c61619b0eb25