Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Tadashi, Ohkubo"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 95, Iss 2, Pp 214-227 (2004)
Phencyclidine (PCP) produces schizophrenia-like psychosis and acute PCP-intoxications; however, whether glutamate/NMDA-receptor blockade by PCP modulates or not these mechanisms has remained to be clarified. To clarify this mechanism, we determined i
Externí odkaz:
https://doaj.org/article/21f9cc2f93f9477faef94885d371a502
Publikováno v:
Case Reports in Dentistry, Vol 2014 (2014)
We describe a patient with dysphagia and trismus associated with lower jaw inflammation due to phlegmon who developed severe hyponatremia from water intoxication due to excessive water intake after diaphoresis caused by abnormally hot weather. A 63-y
Externí odkaz:
https://doaj.org/article/cc137b7b6c8d4513b420991f000e5ad3
Publikováno v:
Journal of chromatographic science. 58(10)
Here, we developed a novel high-performance liquid chromatography (HPLC) method for quantification of perampanel in clinical practice and investigated the relationships between the plasma concentrations of perampanel obtained by this HPLC method and
Autor:
Yui Mori, Hiroaki Yoshida, Kimishige Shimizutani, Shoko Gamoh, Michiko Nakatsuka, Naotaka Kishimoto, Tadashi Ohkubo, Kazuhiro Matsumoto, Hironori Akiyama, Naohiro Ohshita, Masayuki Nakayama, Hugo Maruyama
Publikováno v:
Clinical and Experimental Dental Research
The aim of this study was to assess knowledge, attitude, behavior, and compliance concerning infection control among dental practitioners in a dental university hospital in Japan. A 12‐item questionnaire about infection control during radiographic
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 43:181-188
SummaryWhat is known and objective The anti-tacrolimus antibodies used in commercial immunoassay methods have cross-reactivity with tacrolimus metabolites. The aim of this study was to investigate differences in the effects of CYP3A5 polymorphism on
Publikováno v:
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology. 28:446-449
Objective This study was to evaluate the effect of new spray-type oral moisturizer containing poly-γ-glutamic acid (γ-PGA). γ-PGA can be classified as a pseudopolyamino acid, which contains only repeated glutamate units. The hygroscopic and moistu
Autor:
Keiichi Satoh, Masaru Echizenya, Tatsuya Shimizu, Hiroaki Kusanagi, Tadashi Ohkubo, Kenichi Mishima
Publikováno v:
Human Psychopharmacology: Clinical and Experimental. 22:365-372
The aim of the present study was to clarify whether subjective sleepiness accurately reflects benzodiazepine-related decline in psychomotor function after taking benzodiazepines (BZPs) in aged people. Subjects were eight healthy, young (mean age, 19.
Autor:
Masatomo Miura, Tadashi Ohkubo
Publikováno v:
Analytical Letters. 39:2405-2415
A simple and sensitive high‐performance liquid chromatography method was developed for the simultaneous quantitative determination of fluvoxamine and its two metabolites, fluvoxamino alcohol and fluvoxamino acid, in human liver microsomes. Chromato
Publikováno v:
British Journal of Clinical Pharmacology. 61:533-537
Aim To examine the effect of grapefruit juice, an inhibitor of CYP3A4 in the small intestine, on the disposition of manidipine enantiomers in healthy subjects. Methods A randomized cross-over study with at least a 2-week wash-out period was performed
Autor:
James N. Higginbotham, Mordechai Muszkat, Hartmut Glaeser, Sheila Shay, Daniel Kurnik, Grant R. Wilkinson, Alastair J. J. Wood, Richard B. Kim, Edna F. Choo, Tadashi Ohkubo
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 317:1012-1018
A major functional component of the blood-brain barrier is P-glycoprotein. In principle, inhibition of this efflux transporter would permit greater distribution of its substrates into the brain and increased central effects. Tariquidar and elacridar,