Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Tadashi, Miyatake"'
Autor:
Masahiro Uemura, Yuya Hatano, Hiroaki Nozaki, Shoichiro Ando, Hajime Kondo, Akira Hanazono, Akira Iwanaga, Hiroyuki Murota, Yosuke Osakada, Masato Osaki, Masato Kanazawa, Mitsuyasu Kanai, Yoko Shibata, Reiko Saika, Tadashi Miyatake, Hitoshi Aizawa, Takeshi Ikeuchi, Hidekazu Tomimoto, Ikuko Mizuta, Toshiki Mizuno, Tomohiko Ishihara, Osamu Onodera
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 94:74-81
BackgroundThis study aimed to clarify the frequency and clinical features of monogenic cerebral small vessel disease (mgCSVD) among patients with adult-onset severe CSVD in Japan.MethodsThis study included patients with adult-onset severe CSVD with a
Autor:
Masahiro, Uemura, Yuya, Hatano, Hiroaki, Nozaki, Shoichiro, Ando, Hajime, Kondo, Akira, Hanazono, Akira, Iwanaga, Hiroyuki, Murota, Yosuke, Osakada, Masato, Osaki, Masato, Kanazawa, Mitsuyasu, Kanai, Yoko, Shibata, Reiko, Saika, Tadashi, Miyatake, Hitoshi, Aizawa, Takeshi, Ikeuchi, Hidekazu, Tomimoto, Ikuko, Mizuta, Toshiki, Mizuno, Tomohiko, Ishihara, Osamu, Onodera
Publikováno v:
Journal of neurology, neurosurgery, and psychiatry.
This study aimed to clarify the frequency and clinical features of monogenic cerebral small vessel disease (mgCSVD) among patients with adult-onset severe CSVD in Japan.This study included patients with adult-onset severe CSVD with an age of onset
Autor:
Masahiro Uemura, Yuya Hatano, Hiroaki Nozaki, Shoichiro Ando, Hajime Kondo, Akira Hanazono, Akira Iwanaga, Hiroyuki Murota, Yosuke Osakada, Masato Osaki, Masato Kanazawa, Mitsuyasu Kanai, Yoko Shibata, Reiko Saika, Tadashi Miyatake, Hitoshi Aizawa, Takeshi Ikeuchi, Hidekazu Tomimoto, Ikuko Mizuta, Toshiki Mizuno
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry; Jan2023, Vol. 94 Issue 1, p74-81, 46p
Autor:
Robert K. Yu, Keiko Tanaka, Tadashi Miyatake, Sayako Hotta, Toshi Ariga, Keiko Hoshi, Yoshihiko Nakatani, Kyoji Taguchi, Iku Utsunomiya
Publikováno v:
Neurochemical Research. 34:149-157
To investigate the pathophysiological mechanisms of immune-mediated peripheral neuropathies, we studied the effects of sera from patients with Guillain-Barré syndrome (GBS) on the Cav2.1 voltage-dependent calcium channel (VDCC) current in Purkinje c
Autor:
Yoshihiko Nakatani, Shinya Tanabe, Kyoji Taguchi, Keiko Hoshi, Tadashi Miyatake, Iku Utsunomiya, Eikichi Yoshihashi, Hideaki Ikejima
Publikováno v:
Experimental Neurology. 210:51-58
We investigated the expression and localization of Kv1 channels in dorsal spinal roots (DRs) and ventral spinal roots (VRs) in rats. Among Kv1.1-1.6 tested by RT-PCR, mRNAs of Kv1.1, 1.2, and 1.5 were moderately expressed, those of Kv1.3 and Kv1.6 we
Autor:
H. Yoshino, Tadashi Miyatake, T. Nagaoka, Keiko Hoshi, Keiko Tanaka, K. Kawakami, Yoshihiko Nakatani, Iku Utsunomiya, Kyoji Taguchi
Publikováno v:
European Neurology. 57:11-18
We performed an electrophysiological study demonstrating inhibition of spontaneous muscle action potentials within a coculture of rat muscle and spinal cord by exposure to serum, as well as purified IgG, from patients with the acute motor axonal neur
Autor:
Sachie Sasaki, Miwa Kawai, Keiko Hoshi, Yousuke Matsushita, Tetsuhiro Fujita, Jin Ren, Iku Utsunomiya, Kyoji Taguchi, Tadashi Miyatake
Publikováno v:
Neurochemical Research. 31:589-596
Voltage-gated K(+) channels contain six membrane spanning segments and a pore-forming domain. We used site-directed mutation to examine the role of specific amino acids in the extracellular region of the pore in Kv1.2. When expressed in CHO cells, a
Autor:
Atsuko Asano, Hiroyuki Aoyagi, Mitsunori Yamada, Iku Utsunomiya, Toshio Ariga, Hiide Yoshino, Kyoji Taguchi, Takumi Nagaoka, Tadashi Miyatake
Publikováno v:
Brain Research. 1057:177-180
We investigated the localization of GalNAc-GD1a biochemically in the human and bovine peripheral nervous system (PNS). The high-performance thin-layer chromatography (HPTLC)-overlay method with rabbit IgG polyclonal antibody against GalNAc-GD1a (anti
Autor:
Nobuya Fujita, Iku Utsunomiya, Tadashi Miyatake, Jin Ren, Hiide Yoshino, Toshio Ariga, Kyoji Taguchi, Hiroyuki Aoyagi
Publikováno v:
Journal of the Neurological Sciences. 225:91-98
We investigated the epitopes and functional role of IgG anti-GalNAc-GD1a antibodies appearing in serum from a patient with Guillain-Barre syndrome (GBS) and IgG anti-GalNAc-GD1a antibody that was produced by immunization of a rabbit with GalNAc-GD1a.
Autor:
Masaaki Odaka, Yukihiro Nishimoto, Tadashi Miyatake, Kyoji Taguchi, Nobuhiro Yuki, Keiichiro Susuki, Mitsunori Yamada, Koichi Hirata, Tetsuji Kobata, Koichi Furukawa, Michiaki Koga
Publikováno v:
Proceedings of the National Academy of Sciences. 101:11404-11409
Molecular mimicry between microbial and self-components is postulated as the mechanism that accounts for the antigen and tissue specificity of immune responses in postinfectious autoimmune diseases. Little direct evidence exists, and research in this