Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Tadashi, Ikegami"'
Autor:
Kazuhito Kawata, Masanori Atsukawa, Kazuyoshi Ohta, Takeshi Chida, Hidenao Noritake, Taeang Arai, Katsuhiko Iwakiri, Satoshi Yasuda, Hidenori Toyoda, Tomomi Okubo, Atsushi Hiraoka, Tsunamasa Watanabe, Haruki Uojima, Akito Nozaki, Joji Tani, Asahiro Morishita, Fujito Kageyama, Yuzo Sasada, Masamichi Nagasawa, Masahiro Matsushita, Tatsuki Oyaizu, Shigeru Mikami, Tadashi Ikegami, Hiroshi Abe, Kentaro Matsuura, Yasuhito Tanaka, Akihito Tsubota
Publikováno v:
Hepatology Communications, Vol 6, Iss 8, Pp 1855-1869 (2022)
Abstract Despite reports of hepatocellular carcinoma (HCC) in patients with chronic hepatitis C virus (HCV) infection after achieving sustained virological response (SVR), only few studies have demonstrated the incidence of other (non‐HCC) malignan
Externí odkaz:
https://doaj.org/article/d76ea7c332bc46b8b68c30a249551641
Autor:
Junichi Iwamoto, Akira Honda, Teruo Miyazaki, Tadakuni Monma, Hajime Ueda, Yukio Morishita, Sho‐ichiro Yara, Takeshi Hirayama, Tadashi Ikegami
Publikováno v:
Hepatology Communications, Vol 5, Iss 12, Pp 2052-2067 (2021)
Western‐style high‐fat/high‐sucrose diet (HFHSD) changes gut microbiota and bile acid (BA) profiles. Because gut microbiota and BAs could influence each other, the mechanism of changes in both by HFHSD is complicated and remains unclear. We fir
Externí odkaz:
https://doaj.org/article/d3534b94f73f41c186aaf3c254ebfbff
Publikováno v:
Metabolites, Vol 13, Iss 7, p 824 (2023)
Taurine, the end product in the sulfur-containing amino acid pathway, is conjugated with bile acids (BAs) in the liver. The rate-limiting enzymes in both taurine synthesis and BA conjugation may be regulated by a nucleus receptor, FXR, that promotes
Externí odkaz:
https://doaj.org/article/fb60b56b112d4d7fa243ddd6c159e0fe
Autor:
Takashi Hibiya, Meiro Tanaka, Mai Matsumura, Ayako Aoki, Tadashi Ikegami, Koji Okudela, Naomi Kawano, Kenichi Ohashi
Publikováno v:
Diagnostic Pathology, Vol 15, Iss 1, Pp 1-6 (2020)
Abstract Background Primary malignant melanoma of the lung (PML) is extremely rare. No precursor lesions of PML have been identified, and little is known about the genetic mutations associated with the disease. Typically, 15–20% of malignant melano
Externí odkaz:
https://doaj.org/article/2a1de85d67b641b3a64799cc358ffbc5
Autor:
Akira Honda, Teruo Miyazaki, Junichi Iwamoto, Takeshi Hirayama, Yukio Morishita, Tadakuni Monma, Hajime Ueda, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Tadashi Ikegami
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 1, Pp 54-69 (2020)
The bile acid (BA) composition in mice is substantially different from that in humans. Chenodeoxycholic acid (CDCA) is an end product in the human liver; however, mouse Cyp2c70 metabolizes CDCA to hydrophilic muricholic acids (MCAs). Moreover, in hum
Externí odkaz:
https://doaj.org/article/b6ca2ce2cff4472a9322001da895e681
Autor:
Hajime Ueda, Akira Honda, Teruo Miyazaki, Yukio Morishita, Takeshi Hirayama, Junichi Iwamoto, Nobuhiro Nakamoto, Tadashi Ikegami
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0271308 (2022)
Cyp2a12-/-Cyp2c70-/- double knockout (DKO) mice have a human-like hydrophobic bile acid (BA) composition and show reduced fertility and liver injury. Ursodeoxycholic acid (UDCA) is a hydrophilic and cytoprotective BA used to treat various liver injur
Externí odkaz:
https://doaj.org/article/447b387dfa67433bbed6aab990bd4a9d
Autor:
Tadakuni Monma, Junichi Iwamoto, Akira Honda, Hajime Ueda, Fumio Kakizaki, Shoichiro Yara, Teruo Miyazaki, Tadashi Ikegami
Publikováno v:
Metabolites, Vol 12, Iss 4, p 331 (2022)
Since intestinal secondary bile acids (BAs) prevent Clostridium difficile infection (CDI), the serum BA profile may be a convenient biomarker for CDI susceptibility in human subjects. To verify this hypothesis, we investigated blood samples from 71 p
Externí odkaz:
https://doaj.org/article/a37c09d0aca749bb8b91976288c1bd63
Autor:
Yuya, Seko, Hirokazu, Takahashi, Hidenori, Toyoda, Hideki, Hayashi, Kanji, Yamaguchi, Michihiro, Iwaki, Masato, Yoneda, Taeang, Arai, Toshihide, Shima, Hideki, Fujii, Asahiro, Morishita, Kazuhito, Kawata, Kengo, Tomita, Miwa, Kawanaka, Yuichi, Yoshida, Tadashi, Ikegami, Kazuo, Notsumata, Satoshi, Oeda, Yoshihiro, Kamada, Yoshio, Sumida, Hideaki, Fukushima, Eiji, Miyoshi, Shinichi, Aishima, Takeshi, Okanoue, Atsushi, Nakajima, Yoshito, Itoh
Publikováno v:
Hepatology Research. 53:312-321
The enhanced liver fibrosis (ELF) test is a noninvasive method for diagnosing hepatic fibrosis in patients with nonalcoholic fatty liver disease (NAFLD). This multicenter cohort study aimed to evaluate the accuracy of the ELF test and compare it with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20e3813f7502343316aa7c77ff24077
https://doi.org/10.1111/hepr.13871
https://doi.org/10.1111/hepr.13871
Autor:
Tadakuni, Monma, Junichi, Iwamoto, Hajime, Ueda, Makoto, Tamamushi, Fumio, Kakizaki, Naoki, Konishi, Shoichiro, Yara, Teruo, Miyazaki, Takeshi, Hirayama, Tadashi, Ikegami, Akira, Honda
Publikováno v:
World Journal of Clinical Cases. 10:12484-12493
Dysbiosis in the intestinal microflora can affect the gut production of microbial metabolites, and toxic substances can disrupt the barrier function of the intestinal wall, leading to the development of various diseases. Decreased levels of Clostridi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a887d2619c3c92a9ea0bd5a57111c8
https://doi.org/10.12998/wjcc.v10.i34.12484
https://doi.org/10.12998/wjcc.v10.i34.12484
Publikováno v:
Metabolites; Volume 13; Issue 7; Pages: 824
Taurine, the end product in the sulfur-containing amino acid pathway, is conjugated with bile acids (BAs) in the liver. The rate-limiting enzymes in both taurine synthesis and BA conjugation may be regulated by a nucleus receptor, FXR, that promotes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::c9584926c055e5826882bb3cd29a978b