Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tadanori Yano"'
Autor:
Haruo Oyashiki, Tadanori Yano
Publikováno v:
JOURNAL OF THE BREWING SOCIETY OF JAPAN. 90:416-423
Autor:
Masataka Ichikawa, Tadanori Yano, Mikiro Nakashima, Shigeru Goto, Shuji Satoh, Kenji Matsuyama
Publikováno v:
Biological and Pharmaceutical Bulletin. 17:1395-1398
The suitability of sampling via microdialysis for a lipophilic drug, valproate (VPA), was evaluated by the elimination rate constant of VPA solution in an in vitro experimental first-order elimination system. The elimination rate constant of VPA in d
Publikováno v:
European Journal of Pharmaceutical Sciences. 1:117-123
An inclusion complex of prostaglandin E 1 (PGE 1 ) with β-cyclodextrin (β-Cyd) or O-carboxymethyl-O-ethyl-β-cyclodextrin (CME-β-CyD) was made as topical preparations in a fatty alcohol/propylene glycol ointment base. When the PGE 1 preparations w
Autor:
Kenji Matsuyama, Yukiko Nakaboh, Shuji Satoh, Masataka Ichikawa, Mikiro Nakashima, Tadanori Yano
Publikováno v:
Pharmaceutical Research. 11:684-686
Microdialysis was applied to determine the in vivo transdermal absorption of methotrexate (MTX) in rats with or without a new penetration enhancer, l-[2-(decylthio)ethyl]azacyclopentan-2-one (HPE-101). A solution composed of 2.5 mM MTX and 3% (w/v) H
Publikováno v:
The Journal of pharmacy and pharmacology. 45(9)
The penetration enhancer, 1-[2-(decylthio)ethyl]azacyclopentan-2-one (HPE-101), significantly enhanced the excretion of topically applied [14C]indomethacin when dissolved in dipropylene glycol, triethylene glycol, diethylene glycol, 1,3-butylene glyc
Publikováno v:
The Journal of pharmacy and pharmacology. 44(2)
The optimal prescription of transdermal preparations of prostaglandin E1 (PGE1) for treatment of peripheral vascular diseases has been investigated. The chemical stability of PGE1 in fatty alcohol/propylene glycol (FAPG) ointment was markedly improve
Publikováno v:
Journal of pharmacobio-dynamics. 14(12)
Plasters containing methyl salicylate with and without l-menthol and dl-camphor were prepared and topically applied on hairless mouse skin to investigate the effects of l-menthol and dl-camphor on the skin penetration and hydrolysis of methyl salicyl
Autor:
Ryuhei Kodama, Toshikazu Sonoda, Tadanori Yano, Kazuhide Furukawa, Hidetoshi Amano, Kanji Noda, Hiroyuki Ide
Publikováno v:
Xenobiotica. 5:601-609
1. The maximum concentration of radioactivity in blood occurred 2-4 h after oral administration of [14C]H-88 in mouse, rabbit and man. With rat, a maximum concentration was obtained 24 h after administration of the drug at a dose level of 60 mg/kg, b
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 6(6)
1. The main route of elimination of d-limonene administered orally was via the urine in animals and man, 75-95% of the administered radioactivity being excreted in the urine during 2-3 days. Faecal excretion accounted for less than 10% of the dose in
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 5(1)
1. Following oral administration of [14C] H-88 to rat, mouse, quinea-pig and hamster, 40-65% and 5-15% of radioactivity was excreted in urine and faeces respectively during 3 or 4 days. In rabbit, monkey and man, more than 80% of radioactivity was ex