Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Tadanori Yamada"'
Publikováno v:
BioResearch Open Access, Vol 8, Iss 1, Pp 200-209 (2019)
BioResearch Open Access
BioResearch Open Access
The strong barrier function of the blood–brain barrier (BBB) protects the central nervous system (CNS) from xenobiotic substances, while the expression of selective transporters controls the transportation of nutrients between the blood and brain.
Autor:
Takahiro Iwao, Mima Shinji, Toshihide Miyashita, Tadanori Yamada, Tomoki Kabeya, Hiroaki Yuasa, Izumi Ogura, Yuki Imakura, Tomoya Yasujima, Tamihide Matsunaga
Publikováno v:
Drug metabolism and pharmacokinetics. 35(4)
To develop a novel intestinal drug absorption system using intestinal epithelial cells derived from human induced pluripotent stem (iPS) cells, the cells must possess sufficient pharmacokinetic functions. However, the CYP3A4/5 activities of human iPS
Autor:
Yoshiko Kasuya, Tadanori Yamada
Publikováno v:
THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA. 35:027-031
Autor:
Shintaro Nomura, Tadanori Yamada, Takeshi Kasuya, Toshihide Okajima, Katsuyuki Tanizawa, Kenji Tatematsu, Takashi Matsuzaki, Joohee Jung, Shun'ichi Kuroda
Publikováno v:
FEBS Journal. 275:5714-5724
We previously developed the bio-nanocapsule, which consists of hepatitis B virus envelope L proteins. The bio-nanocapsule can be used to deliver genes and drugs specifically to the human liver-derived tissues in xenograft models, presumably by utiliz
Autor:
Kenji Tatematsu, Toshihide Okajima, Takeshi Kasuya, Shun'ichi Kuroda, Takashi Matsuzaki, Katsuyuki Tanizawa, Atsuko Uyeda, Tadanori Yamada
Publikováno v:
Journal of Bioscience and Bioengineering. 106:99-102
Human hepatocyte-specific delivery of green fluorescent protein was succeeded in the mouse xenograft model by fusion with hepatitis B virus surface antigen pre-S regions (pre-S(1+2)), not with each pre-S region. The entire pre-S region would be usefu
Autor:
Michika Kawamura, Shuji Dohi, Hiroki Iida, Motoyasu Takenaka, Shigeaki Tanahashi, Tadanori Yamada
Publikováno v:
THE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA. 27:165-170
36歳, 男性. 強直性脊椎炎 (ankylosing spondylitis: AS) に対して第3腰椎後方椎体骨切り術および脊椎固定術が予定された. 強直性脊椎炎は, 脊椎の関節および関節周囲組織の骨化を伴う進行性慢
Autor:
Hiroko Tada, Masakazu Ueda, Katsuyuki Tanizawa, Masaharu Seno, Shun'ichi Kuroda, Dongwei Yu, Tadanori Yamada, Takayuki Fukuda, Akihiko Kondo, Tuoya
Publikováno v:
IUBMB Life. 58:1-6
The bio-nanocapsule (BNC) is our concept of artificial hollow nanoparticles that have been designed and produced through biotechnological procedures. We proposed an empty virus-like particle, which consists of a recombinant L envelope protein of hepa
Autor:
Tadanori Yamada, Dongwei Yu, Masaharu Seno, Masakazu Ueda, Hidenori Yamada, Takayuki Fukuda, Shun'ichi Kuroda, Akihiko Kondo, Chie Amano, Hiroko Tada, Katsuyuki Tanizawa
Publikováno v:
FEBS Journal. 272:3651-3660
A bio-nanocapsule (BNC), composed of the surface antigen (sAg) of the hepatitis B virus, is an efficient nanomachine with which to accomplish the liver-specific delivery of genes and drugs. Approximately 110 molecules of sAg are associated to form a
Autor:
Jiro Kohda, Tadanori Yamada, Masafumi Yohda, Akihiko Kondo, Hideki Fukuda, Tadashi Maruyama, Takao Yoshida
Publikováno v:
Biochemical Engineering Journal. 18:73-79
The α and β subunits of group II chaperonin from a hyperthermophilic archaeum, Thermococcus strain KS-1, were produced in Escherichia coli . Thermococcus KS-1 α and β chaperonins were purified from a crude cell extract by heat treatment and subse
Autor:
Masakazu Ueda, Shun'ichi Kuroda, Tadanori Yamada, Masaharu Seno, Katsuyuki Tanezawa, Akihiko Kondo
Publikováno v:
KOBUNSHI RONBUNSHU. 61:606-612
B型肝炎ウイルス (hepatitis B virus; HBV) はヒト肝細胞に対し強い感染力を有する. その感染機構を担うHBV表面抗原 (HBV surface antigen; HBsAg) は, 組換え酵母を用いて大量生産が可能であり, 酵母由