Výsledky vyhledávání - "Tadahiro, Yamadori"

Data from Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer

Autor: Masayuki Yamamoto, Ken Itoh, Nobuyuki Hizawa, Tohru Sakamoto, Hiroaki Satoh, Norihiro Kikuchi, Norihiro Haraguchi, Yosuke Matsuno, Tadahiro Yamadori, Yuko Morishima, Yukio Ishii, Shinsuke Homma

Purpose: NF-E2-related factor 2 (Nrf2), a key transcription regulator for antioxidant and detoxification enzymes, is abundantly expressed in cancer cells. In this study, therefore, the role of Nrf2 in cancer cell proliferation and resistance to antic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a79514a9c568ba48413eedbde69c2e7
https://doi.org/10.1158/1078-0432.c.6516951.v1

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Akademický článek

Usefulness of high suction pressure for sufficient tissue collection during endobronchial ultrasound guided transbronchial needle aspiration.

Autor: Takayuki Shiroyama, Norio Okamoto, Hidekazu Suzuki, Motohiro Tamiya, Tadahiro Yamadori, Naoko Morishita, Tomoyuki Otsuka, Satomu Morita, Kanako Kurata, Akira Okimura, Kunimitsu Kawahara, Shinji Sasada, Tomonori Hirashima, Ichiro Kawase

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82787 (2013)

INTRODUCTION: The optimal suction pressure during endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) remains to be determined. The aim of this study was to compare suction pressures for performance in collecting sufficient t

Externí odkaz: https://doaj.org/article/6f2838da36a34277ad6b3eace1f4d147

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Important factors for achieving survival of five years or more in non-small cell lung cancer patients with distant metastasis

Autor: Naoko Morishita, Tomonori Hirashima, Hidekazu Suzuki, Kanako Kurata, Motohiro Tamiya, Norio Okamoto, Tadahiro Yamadori, Takayuki Shiroyama, Ichiro Kawase

Publikováno v: Oncology Letters

In order to examine which factors were important for achieving a ≥5 year survival time in non-small cell lung cancer (NSCLC) patients with distant metastasis, 268 NSCLC patients who received first-line chemotherapy between January 2004 and December

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e640c649c6e5cb6554d56da2f8d68ce
http://europepmc.org/articles/PMC4063572

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The relationship between tyrosine kinase inhibitor therapy and overall survival in patients with non-small cell lung cancer carrying EGFR mutations

Autor: Tomonori Hirashima, Motohiro Tamiya, Kanako Kitai, Tomoyuki Otsuka, Norio Okamoto, Naoko Morishita, Takayuki Shiroyama, Ichiro Kawase, Hidekazu Suzuki, Tadahiro Yamadori

Publikováno v: Chinese Journal of Cancer

For patients with epidermal growth factor receptor (EGFR) mutation-positive lung cancer, the relationship between the dose or duration of treatment with tyrosine kinase inhibitor (TKI) and overall survival remains unclear. Here, we analyzed clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4068cff3ff4c984d80e468a5239d22
http://europepmc.org/articles/PMC3845597

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Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers

Autor: Yuko Minami, Tadahiro Yamadori, Masayuki Yamamoto, Shinsuke Homma, Masayuki Noguchi, Ken Itoh, Yuko Morishima, Koichi Kurishima, Yukio Ishii, Nobuyuki Hizawa

Publikováno v: Oncogene. 31:4768-4777

We previously demonstrated that the transcription factor NF-E2-related factor2 (Nrf2), expressed abundantly in non-small-cell lung cancer (NSCLC) cells, plays a pivotal role in the proliferation and chemoresistance of NSCLC. Here we show that Nrf2-me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807209b5f9ec27f64412770b153b02cb
https://doi.org/10.1038/onc.2011.628

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Resistance to chemotherapy in non-small cell lung cancer with Keap1 gene mutation

Autor: Tadahiro Yamadori, Yuko Minami, Shinsuke Homma, Yukio Ishii, Masayuki Noguchi, Nobuyuki Hizawa, Koichi Kurishima

Publikováno v: International Cancer Conference Journal. 1:63-66

We report the case of a 49-year-old Japanese man with advanced non-small cell lung carcinoma showing a Keap1 gene mutation. Although he received platinum-based first- and second-line chemotherapies, he was judged to have progressive disease because o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f49105d8c6af0a12bd54db20a8c779d
https://doi.org/10.1007/s13691-011-0011-0

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The Gefitinib-Sensitizing Mutant Epidermal Growth Factor Receptor Enables Transformation of a Mouse Fibroblast Cell Line

Autor: Izumi Nagatomo, Tsutomu Yoneda, Yoshiyuki Saito, Yukihiro Yano, Tadahiro Yamadori, Mitsuhiro Yoshida, Yoshitaka Ogata, Mitsugi Furukawa, Tadashi Osaki, Isao Tachibana, Mark I. Greene, Ryo Takahashi, Takashi Kijima, Ichiro Kawase, Toru Kumagai, Koji Inoue

Publikováno v: DNA and Cell Biology. 25:246-251

A specific inhibitor of the Epidermal Growth Factor Receptor (EGFR), Gefitinib, displays significant antitumor effects against non-small cell lung cancers (NSCLC) that express EGFR with mutations in their tyrosine kinase domain. Although previous rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9984839e90348548c1e83460c2d211ed
https://doi.org/10.1089/dna.2006.25.246

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Relationship between progression-free survival and overall survival in patients with advanced non-small cell lung cancer treated with anticancer agents after first-line treatment failure

Autor: Hidekazu, Suzuki, Tomonori, Hirashima, Norio, Okamoto, Tadahiro, Yamadori, Motohiro, Tamiya, Naoko, Morishita, Takayuki, Shiroyama, Sawa, Takeoka, Akio, Osa, Yuichiro, Azuma, Ichiro, Kawase

Publikováno v: Asia-Pacific journal of clinical oncology. 11(2)

The hazard ratio of progression-free survival (PFS-HR) generally does not reflect that of overall survival (OS-HR) in advanced non-small cell lung cancer (NSCLC) patients treated with first-line therapy. Short survival post-progression (SPP) better r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c18efd00fb69b13d1c0218c4f619358f
https://pubmed.ncbi.nlm.nih.gov/24811212

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Usefulness of High Suction Pressure for Sufficient Tissue Collection During Endobronchial Ultrasound Guided Transbronchial Needle Aspiration

Autor: Tomoyuki Otsuka, Shinji Sasada, Naoko Morishita, Tadahiro Yamadori, Tomonori Hirashima, Motohiro Tamiya, Kanako Kurata, Akira Okimura, Hidekazu Suzuki, Takayuki Shiroyama, Ichiro Kawase, Satomu Morita, Kunimitsu Kawahara, Norio Okamoto

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e82787 (2013)

Introduction: The optimal suction pressure during endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) remains to be determined. The aim of this study was to compare suction pressures for performance in collecting sufficient t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c069d579141de6c6814e5cd0bdb68d
http://europepmc.org/articles/PMC3855538

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