Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Tadahide Izumi"'
Autor:
Rajesh Mani, Chloe G. Martin, Kanal E. Balu, Qingding Wang, Piotr Rychahou, Tadahide Izumi, B. Mark Evers, Yasuhiro Suzuki
Publikováno v:
Cells, Vol 13, Iss 2, p 111 (2024)
Cancer-specific CD8+ cytotoxic T cells play important roles in preventing cancer growth, and IFN-γ, in addition to IL-12 and type I interferon, is critical for activating CD8+ cytotoxic T cells. We recently identified the capability of the amino-ter
Externí odkaz:
https://doaj.org/article/c042eed071fe47d4b0aacbacb46c76b1
Publikováno v:
Cells, Vol 12, Iss 20, p 2425 (2023)
Genome instability in cancer cells causes not only point mutations but also structural variations of the genome, including copy number variations (CNVs). It has recently been proposed that CNVs arise in cancer to adapt to a given microenvironment to
Externí odkaz:
https://doaj.org/article/a6a3ab7dfa54459c942b5bfb0aa460cf
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/a5707c4a54fb497981ed39d870433d77
Autor:
Zeta Chow, Jeremy Johnson, Aman Chauhan, Tadahide Izumi, Michael Cavnar, Heidi Weiss, Courtney M. Townsend, Lowell Anthony, Carrigan Wasilchenko, Matthew L. Melton, Jörg Schrader, B. Mark Evers, Piotr Rychahou
Publikováno v:
Cells, Vol 10, Iss 5, p 1261 (2021)
Patients with advanced-stage gastroenteropancreatic neuroendocrine tumors (GEP-NETs) have a poor overall prognosis despite chemotherapy and radiotherapy (e.g., peptide receptor radionuclide therapy (PRRT)). Better treatment options are needed to impr
Externí odkaz:
https://doaj.org/article/6b5223d474e44dc4a6fc947c392a93ae
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 6, Pp 495-508 (2012)
In previous studies, we found that adenomatous polyposis coli (APC) blocks the base excision repair (BER) pathway by interacting with 5′-flap endonuclease 1 (Fen1). In this study, we identify the molecular features that contribute to the formation
Externí odkaz:
https://doaj.org/article/91affa55d05f4d979a0578d0c456dfae
Autor:
Satya Narayan, David A. Ostrov, Fazlul H. Sarkar, Tadahide Izumi, Charles D. Bulkin, Harekrushna Panda, Sanjeev Banerjee, Aruna S. Jaiswal
The recent emerging concept to sensitize cancer cells to DNA-alkylating drugs is by inhibiting various proteins in the base excision repair (BER) pathway. In the present study, we used structure-based molecular docking of DNA polymerase β (Pol-β) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce6ed2a01e96dd4859ec5de5fdc9c94
https://doi.org/10.1158/1541-7786.c.6541951
https://doi.org/10.1158/1541-7786.c.6541951
Autor:
Satya Narayan, David A. Ostrov, Fazlul H. Sarkar, Tadahide Izumi, Charles D. Bulkin, Harekrushna Panda, Sanjeev Banerjee, Aruna S. Jaiswal
Supplementary Data from A Novel Inhibitor of DNA Polymerase β Enhances the Ability of Temozolomide to Impair the Growth of Colon Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdba46818a1c590313624ee9f587fc8
https://doi.org/10.1158/1541-7786.22518502.v1
https://doi.org/10.1158/1541-7786.22518502.v1
Autor:
David Rios-Covian, Lindsay D. Butcher, Amber L. Ablack, Gerco den Hartog, Mason T. Matsubara, Hong Ly, Andrew W. Oates, Guorong Xu, Kathleen M. Fisch, Eric T. Ahrens, Shusuke Toden, Corrie C. Brown, Kenneth Kim, Dzung Le, Lars Eckmann, Bithika Dhar, Tadahide Izumi, Peter B. Ernst, Sheila E. Crowe
While best known for its role in oxidative DNA damage repair, apurinic-apyrimidinic endonuclease-1 (APE1) is a multifunctional protein that regulates multiple host responses during oxidative stress including the reductive activation of transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe004c4f6c31b2bf57a0dc06964a1723
http://hdl.handle.net/10029/625917
http://hdl.handle.net/10029/625917
Autor:
David, Rios-Covian, Lindsay D, Butcher, Amber L, Ablack, Gerco, den Hartog, Mason T, Matsubara, Hong, Ly, Andrew W, Oates, Guorong, Xu, Kathleen M, Fisch, Eric T, Ahrens, Shusuke, Toden, Corrie C, Brown, Kenneth, Kim, Dzung, Le, Lars, Eckmann, Bithika, Dhar, Tadahide, Izumi, Peter B, Ernst, Sheila E, Crowe
Publikováno v:
Antioxidantsredox signaling.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80721b8ff24e1174859f1f98eab9e5d7
https://pubmed.ncbi.nlm.nih.gov/35754343
https://pubmed.ncbi.nlm.nih.gov/35754343
Autor:
Na Ding, Hong Jiang, Pratik Thapa, Yanning Hao, Aziza Alshahrani, Derek Allison, Tadahide Izumi, Vivek M. Rangnekar, Xiaoqi Liu, Qiou Wei
Publikováno v:
The Journal of biological chemistry. 298(7)
High levels of redox enzymes have been commonly observed in various types of human cancer, although whether and how the enzymes contribute to cancer malignancy and therapeutic resistance have yet to be understood. Peroxiredoxin IV (Prx4) is an antiox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688b50e88190bda6128701eb44f68af4
https://pubmed.ncbi.nlm.nih.gov/35697073
https://pubmed.ncbi.nlm.nih.gov/35697073