Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Tadafumi Iino"'
Autor:
Kasem Kulkeaw, Tomoko Inoue, Tadafumi Iino, Kenzaburo Tani, Koichi Akashi, Nancy A. Speck, Yoichi Nakanishi, Daisuke Sugiyama
Publikováno v:
Blood Advances, Vol 1, Iss 20, Pp 1672-1681 (2017)
Abstract: Mechanisms underlying differentiation of embryonic hematopoietic stem/progenitor cells (HSPCs) remain unclear. In mouse, intra-aortic clusters (IACs) form in the aorta-gonad-mesonephros region and acquire HSPC potential after 9.5 days postc
Externí odkaz:
https://doaj.org/article/c7d83399bad14c8fbe4b2bb2c7e11666
Autor:
Atsushi Nonami, Ryu Matsuo, Kouta Funakoshi, Tomohiro Nakayama, Shigenori Goto, Tadafumi Iino, Shigeo Takaishi, Shinichi Mizuno, Koichi Akashi, Masatoshi Eto
Publikováno v:
Cytotherapy. 25(1)
This prospective clinical study aimed to determine the efficacy and prognostic factors of adoptive activated αβT lymphocyte immunotherapy for various refractory cancers. The primary endpoint was overall survival (OS), and the secondary endpoint was
Publikováno v:
Cancer Science
Adult T‐cell leukemia/lymphoma (ATL) is an aggressive lymphoproliferative disease caused by human T‐cell leukemia virus type 1 (HTLV‐1). Multi‐agent chemotherapy can reduce ATL cells but frequently allows relapses within a short period of tim
Autor:
Akihiro Kishimura, Koichi Sasaki, Yoshiki Katayama, Daiki Funamoto, Yoshiki Miyashita, Shigeo Takaishi, Kazuki Sato, Tadafumi Iino, Jun Nagano, Yoko Yamaguchi, Daisuke Asai, Takeshi Mori, Yuji Mishima
Publikováno v:
MedChemComm. 9:783-788
Antibody-dependent cell-mediated cytotoxicity (ADCC) is caused by natural killer (NK) cells upon recognition of antigen-bound IgG via FcγRIIIa. This mechanism is crucial for cytolysis of pathogen-infected cells and monoclonal antibody (mAb)-mediated
Publikováno v:
International Journal of Hematology. 107:311-319
In hematopoiesis, the expression of critical genes is regulated in a stage-specific manner to maintain normal hematopoiesis. Notch1 is an essential gene involved in the commitment and development of the T-cell lineage. However, the regulation of Notc
Autor:
Takahiro Maeda, Koji Kato, Tadafumi Iino, Toshihiro Miyamoto, Yasufumi Uehara, Hirotake Kusumoto, Hirofumi Tsuzuki, Hiromi Iwasaki, Takashi Jiromaru, Takeshi Sugio, Ayano Yurino, Shinya Daitoku, Yuya Kunisaki, Jun Odawara, Katsuto Takenaka, Yasuo Mori, Kohta Miyawaki, Yojiro Arinobu, Koichi Akashi, Yoshikane Kikushige
Publikováno v:
Blood. 129:3332-3343
The developmental pathway for human megakaryocytes remains unclear, and the definition of pure unipotent megakaryocyte progenitor is still controversial. Using single-cell transcriptome analysis, we have identified a cluster of cells within immature
Autor:
Tadafumi, Iino, Shigeo, Takaishi
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 75(2)
Natural killer (NK) cells are innate lymphoid cells important for host defense against patho- gens, and are also thought to play an important role in the immunosurveillance against can- cers. NK cells express surface receptors that interact with targ
Autor:
Toshihiro Miyamoto, Kohta Miyawaki, Kentaro Kohno, Yoshikane Kikushige, Tadafumi Iino, Hiromi Iwasaki, Yojiro Arinobu, Koichi Akashi, Katsuto Takenaka, Hirofumi Tsuzuki, Takahiro Shima
Publikováno v:
Stem Cells. 33:976-987
Previous studies have predicted that reciprocal activation of GATA-1 and PU.1 regulates myelo-erythroid versus myelo-lymphoid lineage commitment in early hematopoiesis. Such PU.1-activating myelo-lymphoid progenitors exist within the lymphoid-primed
Autor:
Ayako Takamori, Masao Matsuoka, Koichi Akashi, Mari Kannagi, Naokuni Uike, Jun Okamura, Atsuhiko Hasegawa, Ilseung Choi, Osamu Miura, Nobukazu Watanabe, Ryuji Tanosaki, Tetsuya Fukuda, Youko Suehiro, Atae Utsunomiya, Shigeo Takaishi, Tadafumi Iino, Amane Sasada, Takanori Teshima
Publikováno v:
British Journal of Haematology. 169:356-367
Summary Adult T cell leukaemia/lymphoma (ATL) is a human T cell leukaemia virus type-I (HTLV-I)-infected T cell malignancy with poor prognosis. We herein developed a novel therapeutic vaccine designed to augment an HTLV-I Tax-specific cytotoxic T lym
Autor:
Kazuki Tanimoto, Koji Kato, Kiyofumi Ohkusu, Masako Kadowaki, Keiji Sakamoto, Katsuto Takenaka, Toshihiro Miyamoto, Hiromi Iwasaki, Nobuyuki Shimono, Noriko Miyake, Tadafumi Iino, Takanori Teshima, Seido Oku, Makiko Kiyosuke, Junichiro Yuda, Koichi Akashi, Yoshikane Kikushige
Publikováno v:
Internal Medicine. 53:1087-1091
Zygomycosis is a lethal and invasive mold infection that is often associated with hematological malignancies. The keys for successful treatment include making a rapid diagnosis and appropriately administering antifungal agents. We herein report the e