Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Tadaaki, Ohgi"'
Autor:
Atsushi Shibata, Hisao Shirohzu, Yusuke Iwakami, Tomoaki Abe, Chisato Emura, Eriko Aoki, Tadaaki Ohgi
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 468-477 (2023)
Small interfering RNA (siRNA) and short hairpin RNA (shRNA) are widely used as RNA interference (RNAi) reagents. Recently, truncated shRNAs that trigger RNAi in a Dicer-independent manner have been developed. We generated a novel class of RNAi reagen
Externí odkaz:
https://doaj.org/article/7fa797aaa0604488b979cd3b9dfb4ed7
Autor:
Junichi Yano, Tadaaki Ohgi, Kazuko Hirabayashi, Kazuchika Takagaki, Yohei Sato, Kae Fujiwara, Toshihiro Ueda, Satoru Sonoke
Supplementary Figure 2 from Tumor Regression in Mice by Delivery of Bcl-2 Small Interfering RNA with Pegylated Cationic Liposomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a037af0f958826f05b9ed53d350b10c
https://doi.org/10.1158/0008-5472.22374741
https://doi.org/10.1158/0008-5472.22374741
Autor:
Junichi Yano, Tadaaki Ohgi, Kazuko Hirabayashi, Kazuchika Takagaki, Yohei Sato, Kae Fujiwara, Toshihiro Ueda, Satoru Sonoke
Supplementary Table 1 from Tumor Regression in Mice by Delivery of Bcl-2 Small Interfering RNA with Pegylated Cationic Liposomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d984e9cc7602e7cf69888e5a37a64a7a
https://doi.org/10.1158/0008-5472.22374738
https://doi.org/10.1158/0008-5472.22374738
Autor:
Junichi Yano, Tadaaki Ohgi, Kazuko Hirabayashi, Kazuchika Takagaki, Yohei Sato, Kae Fujiwara, Toshihiro Ueda, Satoru Sonoke
Supplementary Figure 1 from Tumor Regression in Mice by Delivery of Bcl-2 Small Interfering RNA with Pegylated Cationic Liposomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839892921300b93ce448a42a493334ae
https://doi.org/10.1158/0008-5472.22374744.v1
https://doi.org/10.1158/0008-5472.22374744.v1
Autor:
Junichi Yano, Tadaaki Ohgi, Kazuko Hirabayashi, Kazuchika Takagaki, Yohei Sato, Kae Fujiwara, Toshihiro Ueda, Satoru Sonoke
The pharmacokinetics and antitumor activity of pegylated small interfering RNA (siRNA)/cationic liposome complexes were studied after systemic administration to mice. We designed pegylated-lipid carriers for achieving increased plasma concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83b26225a542ea55c1aa86776795955c
https://doi.org/10.1158/0008-5472.c.6497562
https://doi.org/10.1158/0008-5472.c.6497562
Autor:
Saori Itami, Yutaka Eguchi, Takayuki Mizutani, Eriko Aoki, Tadaaki Ohgi, Masahiko Kuroda, Takahiro Ochiya, Nobuyuki Kato, Hiroshi I Suzuki, Norifumi Kawada, Yoshiki Murakami
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
MicroRNAs (miRNAs) serve important roles in regulating various physiological activities through RNA interference (RNAi). miR-122 is an important mediator of RNAi that is known to control hepatitis C virus (HCV) replication and is being investigated i
Externí odkaz:
https://doaj.org/article/71cf4b98f1c4455b9df220e17ef1a424
Autor:
Tomohiro Hamasaki, Hiroshi Suzuki, Hisao Shirohzu, Takahiro Matsumoto, Corina N D'Alessandro-Gabazza, Paloma Gil-Bernabe, Daniel Boveda-Ruiz, Masahiro Naito, Tetsu Kobayashi, Masaaki Toda, Takayuki Mizutani, Osamu Taguchi, John Morser, Yutaka Eguchi, Masahiko Kuroda, Takahiro Ochiya, Hirotake Hayashi, Esteban C Gabazza, Tadaaki Ohgi
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42655 (2012)
RNA interference (RNAi) is being widely used in functional gene research and is an important tool for drug discovery. However, canonical double-stranded short interfering RNAs are unstable and induce undesirable adverse effects, and thus there is no
Externí odkaz:
https://doaj.org/article/82716a38560e48259e74f1950b23ae7a
Autor:
Masakatsu Takanashi, Masahiko Kuroda, Shinobu Ueda, Takayuki Mizutani, Akio Ishikawa, Katsuko Sudo, Noriko Gotoh, Takahiro Ochiya, Shin-ichiro Ohno, Koji Fujita, Nagahisa Matsuyama, Tadaaki Ohgi
Publikováno v:
Molecular Therapy. 21(1):185-191
Despite the therapeutic potential of nucleic acid drugs, their clinical application has been limited in part by a lack of appropriate delivery systems. Exosomes or microvesicles are small endosomally derived vesicles that are secreted by a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd817844c2e5b13bc39fb94ca378dbaa
Autor:
Tadaaki Ohgi, Junichi Yano
Publikováno v:
Pharmaceutical Process Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d46b77ef156d605550cfbb09868e7d6a
https://doi.org/10.1002/9783527633678.ch17
https://doi.org/10.1002/9783527633678.ch17
Autor:
Hirofumi Masuda, Seigo Nagata, Koichi Uetake, Natsuhisa Oka, Tomohiro Hamasaki, Kazuchika Takagaki, Junichi Yano, Takeshi Wada, Tadaaki Ohgi
Publikováno v:
Nucleic Acids Research
Though medicines that target mRNA are under active investigation, there has been little or no effort to develop mRNA itself as a medicine. Here, we report the synthesis of a 130-nt mRNA sequence encoding a 33-amino-acid peptide that includes the sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3c41e62802a594291aa157c7e6d58d
http://europepmc.org/articles/PMC2995060
http://europepmc.org/articles/PMC2995060