Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Taco W A, Kooij"'
Autor:
Laura E. de Vries, Patrick A. M. Jansen, Catalina Barcelo, Justin Munro, Julie M. J. Verhoef, Charisse Flerida A. Pasaje, Kelly Rubiano, Josefine Striepen, Nada Abla, Luuk Berning, Judith M. Bolscher, Claudia Demarta-Gatsi, Rob W. M. Henderson, Tonnie Huijs, Karin M. J. Koolen, Patrick K. Tumwebaze, Tomas Yeo, Anna C. C. Aguiar, Iñigo Angulo-Barturen, Alisje Churchyard, Jake Baum, Benigno Crespo Fernández, Aline Fuchs, Francisco-Javier Gamo, Rafael V. C. Guido, María Belén Jiménez-Diaz, Dhelio B. Pereira, Rosemary Rochford, Camille Roesch, Laura M. Sanz, Graham Trevitt, Benoit Witkowski, Sergio Wittlin, Roland A. Cooper, Philip J. Rosenthal, Robert W. Sauerwein, Joost Schalkwijk, Pedro H. H. Hermkens, Roger V. Bonnert, Brice Campo, David A. Fidock, Manuel Llinás, Jacquin C. Niles, Taco W. A. Kooij, Koen J. Dechering
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here, de Vries et al. perform a pre-clinical characterization of the antimalarial compound MMV693183: the compound targets acetyl-CoA synthetase, has efficacy in humanized mice against Plasmodium falciparum infection, blocks transmission to mosquito
Externí odkaz:
https://doaj.org/article/5a569da9aa694e86aa5e04aa0c21ba75
Autor:
Sylwia D. Boltryk, Armin Passecker, Arne Alder, Eilidh Carrington, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Alex van der Starre, Hans-Peter Beck, Robert W. Sauerwein, Taco W. A. Kooij, Nicolas M. B. Brancucci, Nicholas I. Proellochs, Tim-Wolf Gilberger, Till S. Voss
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
During each replication cycle of P. falciparum in the human bloodstream, a small proportion of parasites commits to sexual development and differentiates into transmission-relevant gametocytes. Applying CRISPR-based genome editing, Boltryk et al. eng
Externí odkaz:
https://doaj.org/article/bdde91798fe34a80b40c88b2bfa92cdd
Autor:
Felix Evers, Alfredo Cabrera-Orefice, Dei M. Elurbe, Mariska Kea-te Lindert, Sylwia D. Boltryk, Till S. Voss, Martijn A. Huynen, Ulrich Brandt, Taco W. A. Kooij
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Applying complexome profiling, Evers et al. unravel the composition of mitochondrial oxidative phosphorylation complexes in P. falciparum asexual and sexual blood stages. Abundance of these complexes differs between both stages, supporting the hypoth
Externí odkaz:
https://doaj.org/article/84175595e535442092eacbb5b96bf88c
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010124 (2021)
The Apicomplexa phylum comprises thousands of distinct intracellular parasite species, including coccidians, haemosporidians, piroplasms, and cryptosporidia. These parasites are characterized by complex and divergent life cycles occupying a variety o
Externí odkaz:
https://doaj.org/article/c25c93579c3e4132ab0833a335ef8d0a
Autor:
Selma L. van Esveld, Lisette Meerstein‐Kessel, Cas Boshoven, Jochem F. Baaij, Konstantin Barylyuk, Jordy P. M. Coolen, Joeri van Strien, Ronald A. J. Duim, Bas E. Dutilh, Daniel R. Garza, Marijn Letterie, Nicholas I. Proellochs, Michelle N. de Ridder, Prashanna Balaji Venkatasubramanian, Laura E. de Vries, Ross F. Waller, Taco W. A. Kooij, Martijn A. Huynen
Publikováno v:
mSphere, Vol 6, Iss 5 (2021)
The unique biology and medical relevance of the mitochondrion of the malaria parasite Plasmodium falciparum
Externí odkaz:
https://doaj.org/article/eb272dbbf8e14a50ad91944a92d601df
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Apicomplexan parasites, such as Toxoplasma gondii and Plasmodium falciparum, are the cause of many important human and animal diseases. While T. gondii tachyzoites replicate through endodyogeny, during which two daughter cells are formed wit
Externí odkaz:
https://doaj.org/article/7b853ce546c24ffd98c13f7fa108dcc8
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
The functions of many putative membrane transport proteins of malaria parasites are unknown. Here, Kenthirapalan et al. use mutant strains carrying targeted gene deletions to study the functions of 35 such proteins during the life cycle of Plasmodium
Externí odkaz:
https://doaj.org/article/8e9d4eee72da47c997cff6e4f86bb1c1
Autor:
Patrick A. M. Jansen, Taco W. A. Kooij, Martijn W. Vos, Manuel Llinás, Floris P. J. T. Rutjes, Sergio Wittlin, Gabrielle A. Josling, Iñigo Angulo-Barturen, Stacy A. Reeves, Julie M. J. Verhoef, Karin M. J. Koolen, Erik L. Allman, Karen Miller, Helmi Pett, Suzanne Jackowski, Judith M. Bolscher, Robert W. Sauerwein, L. E. De Vries, María Belén Jiménez-Díaz, Richard H. Blaauw, Peter N. M. Botman, Graham P. Trevitt, Christien A. Beuckens-Schortinghuis, Brice Campo, Christian Scheurer, Sibylle Sax, Koen J. Dechering, Pedro H. H. Hermkens, Roger Bonnert, Christoph Fischli, Joost Schalkwijk
Publikováno v:
Science Translational Medicine. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6549a95b6758c0507a3f1f8b74eaf188
https://doi.org/10.1126/scitranslmed.abg8900
https://doi.org/10.1126/scitranslmed.abg8900
Publikováno v:
mBio
Mbio, 12, 4
mBio, Vol 12, Iss 4 (2021)
Mbio, 12
Mbio, 12, 4
mBio, Vol 12, Iss 4 (2021)
Mbio, 12
Contains fulltext : 238259.pdf (Publisher’s version ) (Open Access) Apicomplexan parasites, such as Toxoplasma gondii and Plasmodium falciparum, are the cause of many important human and animal diseases. While T. gondii tachyzoites replicate throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce591d15b820f16ec7cd37eddd959c33
http://europepmc.org/articles/PMC8406264
http://europepmc.org/articles/PMC8406264
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89718 (2014)
Iron-sulfur [Fe-S] clusters are ubiquitous and critical cofactors in diverse biochemical processes. They are assembled by distinct [Fe-S] cluster biosynthesis pathways, typically in organelles of endosymbiotic origin. Apicomplexan parasites, includin
Externí odkaz:
https://doaj.org/article/2f3397842fc04828b62d702492f684ff