Effects of simulated space conditions on CD4+ T cells: a multi modal analysis.

Autor: Miranda S; Radiobiology Unit, Institute for Nuclear Medical Applications, Belgian Nuclear Research Centre SCK CEN, Mol, Belgium.; Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium., Vermeesen R; Radiobiology Unit, Institute for Nuclear Medical Applications, Belgian Nuclear Research Centre SCK CEN, Mol, Belgium., Janssen A; Radiobiology Unit, Institute for Nuclear Medical Applications, Belgian Nuclear Research Centre SCK CEN, Mol, Belgium., Rehnberg E; Radiobiology Unit, Institute for Nuclear Medical Applications, Belgian Nuclear Research Centre SCK CEN, Mol, Belgium.; Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium., Etlioglu E; Radiobiology Unit, Institute for Nuclear Medical Applications, Belgian Nuclear Research Centre SCK CEN, Mol, Belgium., Baatout S; Radiobiology Unit, Institute for Nuclear Medical Applications, Belgian Nuclear Research Centre SCK CEN, Mol, Belgium.; Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium., Tabury K; Radiobiology Unit, Institute for Nuclear Medical Applications, Belgian Nuclear Research Centre SCK CEN, Mol, Belgium.; Department of Biomedical Engineering, College of Engineering and Computing, University of South Carolina, Columbia, SC, United States., Baselet B; Radiobiology Unit, Institute for Nuclear Medical Applications, Belgian Nuclear Research Centre SCK CEN, Mol, Belgium.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Sep 02; Vol. 15, pp. 1443936. Date of Electronic Publication: 2024 Sep 02 (Print Publication: 2024).

Radiation-induced DNA double-strand breaks in cortisol exposed fibroblasts as quantified with the novel foci-integrated damage complexity score (FIDCS).

Autor: Radstake WE; Radiobiology Unit, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium.; Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium., Parisi A; Radiation Protection Dosimetry and Calibration Expert Group, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium.; Department of Radiation Oncology, Mayo Clinic, Jacksonville, FL, USA., Miranda S; Radiobiology Unit, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium.; Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium., Gautam K; Radiobiology Unit, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium., Vermeesen R; Radiobiology Unit, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium., Rehnberg E; Radiobiology Unit, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium.; Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium., Tabury K; Radiobiology Unit, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium.; Department of Biomedical Engineering, University of South Carolina, Columbia, USA., Coppes R; Department of Biomedical Sciences of Cells and Systems, Section of Molecular Cell Biology, University of Groningen, University Medical Center Groningen, 9713, Groningen, The Netherlands.; Department of Radiation Oncology and Particle Therapy Research Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., van Goethem MJ; Department of Radiation Oncology and Particle Therapy Research Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Brandenburg S; Department of Radiation Oncology and Particle Therapy Research Center, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Weber U; Biophysics Division, GSI Helmholtzzentrum Für Schwerionenforschung GmbH, Darmstadt, Germany., Fournier C; Biophysics Division, GSI Helmholtzzentrum Für Schwerionenforschung GmbH, Darmstadt, Germany., Durante M; Biophysics Division, GSI Helmholtzzentrum Für Schwerionenforschung GmbH, Darmstadt, Germany.; Institute for Condensed Matter Physics, Technische Universität Darmstadt, Darmstadt, Germany., Baselet B; Radiobiology Unit, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium. bjorn.baselet@sckcen.be., Baatout S; Radiobiology Unit, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium.; Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.

Publikováno v: Scientific reports [Sci Rep] 2024 May 06; Vol. 14 (1), pp. 10400. Date of Electronic Publication: 2024 May 06.

How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?

Autor: Davis T; Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, USA., Tabury K; Laboratory of Radiobiology, Belgian Nuclear Research Centre, SCK CEN, Mol, Belgium., Zhu S; Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, USA., Angeloni D; Institute of Biorobotics, Scuola Superiore Sant'Anna, Pisa, Italy., Baatout S; Laboratory of Radiobiology, Belgian Nuclear Research Centre, SCK CEN, Mol, Belgium., Benchoua A; ISTEM, CECS, AFM-Téléthon, Corbeil-Essonnes, France., Bereiter-Hahn J; Institute for Cell Biology and Neurobiology, Goethe University Frankfurt am Main, Frankfurt am Main, Germany., Bottai D; Department Pharmaceutical Sciences, University of Milan, Milan, Italy., Buchheim JI; Laboratory of 'Translational Research, Stress & Immunity', Department of Anesthesiology, LMU University Hospital Munich, Munich, Germany., Calvaruso M; Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefalù, Italy., Carnero-Diaz E; Institute of Systematics, Evolution, Biodiversity, Sorbonne University, NMNH, CNRS, EPHE, UA, Paris, France., Castiglioni S; Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy., Cavalieri D; Department of Biology, University of Florence, Florence, Italy., Ceccarelli G; Department of Public Health, Experimental Medicine and Forensic, University of Pavia, Pavia, Italy., Choukér A; Laboratory of 'Translational Research, Stress & Immunity', Department of Anesthesiology, LMU University Hospital Munich, Munich, Germany., Cialdai F; ASAcampus Joint Laboratory, ASA Research Division, DSBSC-University of Florence, Florence, Italy., Ciofani G; Smart Bio-Interfaces, Istituto Italiano di Tecnologia, Pontedera, PI, 56025, Italy., Coppola G; Institute of Applied Science and Intelligent Systems - CNR, Naples, Italy., Cusella G; Department of Public Health, Experimental Medicine and Forensic, University of Pavia, Pavia, Italy., Degl'Innocenti A; Department of Medical Biotechnologies, University of Siena, Italy and Smart Bio-Interfaces, IIT, Pontedera, PI, Italy., Desaphy JF; Department of Precision and Regenerative Medicine, University of Bari 'Aldo Moro', Bari, Italy., Frippiat JP; Stress, Immunity, Pathogens Laboratory, SIMPA, Université de Lorraine, Nancy, France., Gelinsky M; Centre for Translational Bone, Joint & Soft Tissue Research, TU Dresden, Dresden, Germany., Genchi G; Smart Bio-Interfaces, Istituto Italiano di Tecnologia, Pontedera, PI, 56025, Italy., Grano M; Department of Precision and Regenerative Medicine, University of Bari 'Aldo Moro', Bari, Italy., Grimm D; Department of Microgravity and Translational Regenerative Medicine, Otto-von-Guericke-University Magdeburg, Germany & Dept of Biomedicine, Aarhus University, Aarhus, Denmark., Guignandon A; SAINBIOSE, INSERM U1059, Université Jean Monnet, Saint-Etienne, F-42000, France., Hahn C; European Space Agency, ESTEC, Noordwijk, The Netherlands., Hatton J; European Space Agency, ESTEC, Noordwijk, The Netherlands., Herranz R; Centro de Investigaciones Biológicas Margarita Salas (CSIC), Madrid, Spain., Hellweg CE; Radiation Biology Department, Institute of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany., Iorio CS; CREST-ATM, Université libre de Bruxelles, Bruxelles, Belgium., Karapantsios T; Faculty of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece., van Loon JJWA; Amsterdam University Medical Center, ACTA/VU, Amsterdam, Netherlands., Lulli M; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Maier J; Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy., Malda J; Department of Orthopaedics, University Medical Center Utrecht & Department of Clinical Sciences, Utrecht University, Utrecht, The Netherlands., Mamaca E; European and International Affairs Department, Ifremer centre Bretagne, Plouzané, France., Morbidelli L; Department of Life Sciences, University of Siena, Siena, Italy., van Ombergen A; European Space Agency, ESTEC, Noordwijk, The Netherlands., Osterman A; Max von Pettenkofer Institute, Virology, LMU Munich & DZIF, Partner Site Munich, Munich, Germany., Ovsianikov A; 3D Printing and Biofabrication, Institute of Materials Science and Technology, TU Wien, Vienna, Austria., Pampaloni F; Buchmann Inst. for Molecular Life Sciences, Goethe-Universität Frankfurt am Main, Frankfurt am Main, Germany., Pavezlorie E; Ludwig Boltzmann Institute for Traumatology, Research Center in Cooperation with AUVA, Vienna, Austria., Pereda-Campos V; GSBMS/URU EVOLSAN - Medecine Evolutive, Université Paul Sabatier Toulouse III, Toulouse, France., Przybyla C; MARBEC, Université de Montpellier, CNRS, Ifremer, IRD, Palavas les Flots, France., Puhl C; Space Applications NV/SA for European Space Agency, Noordwijk, The Netherlands., Rettberg P; DLR, Institute of Aerospace Medicine, Research Group Astrobiology, Köln, Germany., Rizzo AM; Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy., Robson-Brown K; Department of Engineering Mathematics, and Department of Anthropology and Archaeology, University of Bristol, Bristol, UK., Rossi L; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Russo G; Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefalù, Italy., Salvetti A; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Santucci D; Center for Behavioural Sciences and Mental Health, Istituto Superiore Sanità, Rome, Italy., Sperl M; DLR-MP, Cologne, Germany., Tavella S; IRCCS Ospedale Policlinico San Martino and University of Genoa, DIMES, Genoa, Italy., Thielemann C; BioMEMS lab, University of Applied Sciences Aschaffenburg, Aschaffenburg, Germany., Willaert R; Research Group NAMI and NANO, Vrije Universiteit Brussels, Brussels, Belgium., Szewczyk N; Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, USA. szewczyk@ohio.edu., Monici M; ASAcampus Joint Laboratory, ASA Research Division, DSBSC-University of Florence, Florence, Italy. monica.monici@unifi.it.

Publikováno v: NPJ microgravity [NPJ Microgravity] 2024 Feb 10; Vol. 10 (1), pp. 16. Date of Electronic Publication: 2024 Feb 10.

Whole transcriptome analysis highlights nutrient limitation of nitrogen cycle bacteria in simulated microgravity.

Autor: Verbeelen T; Nuclear Medical Applications, Belgian Nuclear Research Centre (SCK CEN), Boeretang 200, 2400, Mol, Belgium.; Center for Microbial Ecology and Technology (CMET), Ghent University, Coupure Links 653, 9000, Ghent, Belgium., Fernandez CA; Center for Microbial Ecology and Technology (CMET), Ghent University, Coupure Links 653, 9000, Ghent, Belgium., Nguyen TH; Department of Proteomics and Microbiology, University of Mons, Av. Du Champs de Mars 6, 7000, Mons, Belgium., Gupta S; Nuclear Medical Applications, Belgian Nuclear Research Centre (SCK CEN), Boeretang 200, 2400, Mol, Belgium., Aarts R; Nuclear Medical Applications, Belgian Nuclear Research Centre (SCK CEN), Boeretang 200, 2400, Mol, Belgium., Tabury K; Nuclear Medical Applications, Belgian Nuclear Research Centre (SCK CEN), Boeretang 200, 2400, Mol, Belgium., Leroy B; Department of Proteomics and Microbiology, University of Mons, Av. Du Champs de Mars 6, 7000, Mons, Belgium., Wattiez R; Department of Proteomics and Microbiology, University of Mons, Av. Du Champs de Mars 6, 7000, Mons, Belgium., Vlaeminck SE; Research Group of Sustainable Energy, Air and Water Technology, Department of Bioscience Engineering, University of Antwerp, Groenenborgerlaan 171, 2020, Antwerp, Belgium.; Centre for Advanced Process Technology for Urban REsource Recovery (CAPTURE), Frieda Saeysstraat 1, 9052, Ghent, Belgium., Leys N; Nuclear Medical Applications, Belgian Nuclear Research Centre (SCK CEN), Boeretang 200, 2400, Mol, Belgium., Ganigué R; Center for Microbial Ecology and Technology (CMET), Ghent University, Coupure Links 653, 9000, Ghent, Belgium.; Centre for Advanced Process Technology for Urban REsource Recovery (CAPTURE), Frieda Saeysstraat 1, 9052, Ghent, Belgium., Mastroleo F; Nuclear Medical Applications, Belgian Nuclear Research Centre (SCK CEN), Boeretang 200, 2400, Mol, Belgium. Felice.mastroleo@sckcen.be.

Publikováno v: NPJ microgravity [NPJ Microgravity] 2024 Jan 10; Vol. 10 (1), pp. 3. Date of Electronic Publication: 2024 Jan 10.

How do gravity alterations affect animal and human systems at a cellular/tissue level?

Autor: Cialdai F; ASAcampus Joint Laboratory, ASA Res. Div., DSBSC-University of Florence, Florence, Italy., Brown AM; Honors Tutorial College, Ohio University, Athens, OH, USA., Baumann CW; Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, USA., Angeloni D; Inst. of Biorobotics, Scuola Superiore Sant'Anna, Pisa, Italy., Baatout S; Radiobiology Unit, Belgian Nuclear Research Centre (SCK CEN) Boeretang 200, 2400, Mol, Belgium., Benchoua A; ISTEM, CECS, AFM-Téléthon, Corbeil-Essonnes, France., Bereiter-Hahn J; Inst. for Cell and Neurobiol, Goethe University Frankfurt am Main, Frankfurt am Main, Germany., Bottai D; Dept. Pharmaceutical Sciences, University of Milan, Milan, Italy., Buchheim JI; Laboratory of 'Translational Research, Stress & Immunity', Department of Anesthesiology, LMU University Hospital Munich, Munich, Germany., Calvaruso M; Inst. Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefalù, Italy., Carnero-Diaz E; Inst. Systematic, Evolution, Biodiversity, Sorbonne University, NMNH, CNRS, EPHE, UA, Paris, France., Castiglioni S; Dept. of Biomedical and Clinical Sciences, University of Milan, Milan, Italy., Cavalieri D; Dept. of Biology, University of Florence, Florence, Italy., Ceccarelli G; Dept of Public Health, Experimental Medicine and Forensic, University of Pavia, Pavia, Italy., Choukér A; Laboratory of 'Translational Research, Stress & Immunity', Department of Anesthesiology, LMU University Hospital Munich, Munich, Germany., Ciofani G; Smart Bio-Interfaces, Istituto Italiano di Tecnologia, 56025, Pontedera (PI), Italy., Coppola G; Institute of Applied Science and Intelligent Sistems - CNR, Naples, Italy., Cusella G; Dept of Public Health, Experimental Medicine and Forensic, University of Pavia, Pavia, Italy., Degl'Innocenti A; Dept Medical Biotechnologies, University of Siena, Siena, Italy.; Smart Bio-Interfaces, IIT, Pontedera (PI), Italy., Desaphy JF; Dept. Precision and Regenerative Medicine, University of Bari 'Aldo Moro', Bari, Italy., Frippiat JP; Stress, Immunity, Pathogens Laboratory, SIMPA, Université de Lorraine, Nancy, France., Gelinsky M; Centre for Translational Bone, Joint & Soft Tissue Research, TU Dresden, Dresden, Germany., Genchi G; Smart Bio-Interfaces, Istituto Italiano di Tecnologia, 56025, Pontedera (PI), Italy., Grano M; Dept. Precision and Regenerative Medicine, University of Bari 'Aldo Moro', Bari, Italy., Grimm D; Dept. Microgravity and Translational Regenerative Medicine, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.; Dept of Biomedicine, Aarhus University, Aarhus, Denmark., Guignandon A; SAINBIOSE, INSERM U1059, Université Jean Monnet, F-42000, Saint-Etienne, France., Hahn C; European Space Agency, Paris, France., Hatton J; European Space Agency, Paris, France., Herranz R; Centro de Investigaciones Biológicas Margarita Salas (CSIC), Madrid, Spain., Hellweg CE; Radiation Biology Dept., Inst. of Aerospace Medicine, German Aerospace Center (DLR), Cologne, Germany., Iorio CS; CREST-ATM, Université libre de Bruxelles, Bruxelles, Belgium., Karapantsios T; Faculty of Chemistry, Aristotle Univeristy of Thessaloniki, Thessaloniki, Greece., van Loon J; Amsterdam University Medical Center, ACTA/VU, Amsterdam, The Netherlands., Lulli M; Dept. Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Maier J; Dept. of Biomedical and Clinical Sciences, University of Milan, Milan, Italy., Malda J; Dept. Orthopaedics, Univ. Med. Center Utrecht & Dept. Clinical Sciences, Utrecht Univ, Utrecht, The Netherlands., Mamaca E; European and International Affairs Dept, Ifremer centre Bretagne, Plouzané, France., Morbidelli L; Dept. Life Sciences, Univ. of Siena, Siena, Italy., van Ombergen A; European Space Agency, Paris, France., Osterman A; Max von Pettenkofer Institute, Virology, LMU Munich & DZIF, Partner Site Munich, Munich, Germany., Ovsianikov A; 3D Printing and Biofabrication, Inst. Materials Science and Technology, TU Wien, Vienna, Austria., Pampaloni F; Buchmann Inst. for Molecular Life Sciences, Goethe-Universität Frankfurt am Main, Frankfurt am Main, Germany., Pavezlorie E; Ludwig Boltzmann Inst. for Traumatology, Res. Center in Cooperation with AUVA, Vienna, Austria., Pereda-Campos V; GSBMS/URU EVOLSAN - Medecine Evolutive, Université Paul Sabatier Toulouse III, Toulouse, France., Przybyla C; MARBEC, Univ Montpellier, CNRS, Ifremer, IRD, Palavas les Flots, France., Puhl C; Space Applications NV/SA for European Space Agency, Houston, USA., Rettberg P; DLR, Inst of Aerospace Medicine, Research Group Astrobiology, Köln, Germany., Risaliti C; ASAcampus Joint Laboratory, ASA Res. Div., DSBSC-University of Florence, Florence, Italy., Rizzo AM; Dept. of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy., Robson-Brown K; Dept of Engineering Mathematics, and Dept of Anthropology and Archaeology, University of Bristol, Bristol, UK., Rossi L; Dept. Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Russo G; Inst. Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), Cefalù, Italy., Salvetti A; Dept. Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Santucci D; Center for Behavioural Sciences and Mental Health, Ist. Superiore Sanità, Rome, Italy., Sperl M; DLR-MP, Cologne, Germany., Strollo F; Endocrinology and Metabolism Unit, IRCCS San Raffaele Pisana, Rome, Italy., Tabury K; Radiobiology Unit, Belgian Nuclear Research Centre (SCK CEN) Boeretang 200, 2400, Mol, Belgium., Tavella S; IRCCS Ospedale Policlinico San Martino and University of Genoa, DIMES, Genoa, Italy., Thielemann C; BioMEMS lab, University of Applied Sciences Aschaffenburg, Aschaffenburg, Germany., Willaert R; Research Group NAMI and NANO, Vrije Universiteit Brussels, Brussels, Belgium., Szewczyk NJ; Heritage College of Osteopathic Medicine, Ohio University, Athens, OH, USA., Monici M; ASAcampus Joint Laboratory, ASA Res. Div., DSBSC-University of Florence, Florence, Italy. monica.monici@unifi.it.

Publikováno v: NPJ microgravity [NPJ Microgravity] 2023 Oct 21; Vol. 9 (1), pp. 84. Date of Electronic Publication: 2023 Oct 21.