Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Tabrez AS Mohammad"'
Autor:
Subapriya Rajamanickam, Jun Hyoung Park, Panneerdoss Subbarayalu, Santosh Timilsina, Kaitlyn Bates, Pooja Yadav, Saif S. R. Nirzhor, Vijay Eedunuri, Tabrez A. Mohammad, Kwang Hwa Jung, Benjamin Onyeagucha, Nourhan Abdelfattah, Raymond Benevides, Grace Lee, Yidong Chen, Ratna Vadlamudi, Andrew Brenner, Virginia Kaklamani, Ismail Jatoi, John Kuhn, Robert Hromas, Yogesh K. Gupta, Benny A. Kaipparettu, Jack L. Arbiser, Manjeet K. Rao
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
A report of the small molecule Carbazole Blue demonstrates inhibition of breast cancer growth and metastasis without adverse effects on normal tissue.
Externí odkaz:
https://doaj.org/article/7a4cae1b109747c5bf6ef01173eb2df8
Publikováno v:
BMC Genomics, Vol 20, Iss S1, Pp 17-29 (2019)
Abstract Background Cell lines form the cornerstone of cell-based experimentation studies into understanding the underlying mechanisms of normal and disease biology including cancer. However, it is commonly acknowledged that contamination of cell lin
Externí odkaz:
https://doaj.org/article/035fd043f5af413f8fbeefbcecd26068
Autor:
Subbarayalu Panneerdoss, Suryavathi Viswanadhapalli, Nourhan Abdelfattah, Benjamin C. Onyeagucha, Santosh Timilsina, Tabrez A. Mohammad, Yidong Chen, Michael Drake, Kristiina Vuori, T. Rajendra Kumar, Manjeet K. Rao
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Although phagocytic clearance of apoptotic germ cells by Sertoli cells is essential for spermatogenesis, little of the mechanism is known. Here the authors show that Sertoli cells employ LC3-associated phagocytosis (LAP) by recruiting autophagy membe
Externí odkaz:
https://doaj.org/article/14e208c481df43b3b2eb76f2b8f0b5a9
Autor:
Zhen Wei, Subbarayalu Panneerdoss, Santosh Timilsina, Jingting Zhu, Tabrez A. Mohammad, Zhi-Liang Lu, João Pedro de Magalhães, Yidong Chen, Rong Rong, Yufei Huang, Manjeet K. Rao, Jia Meng
Publikováno v:
International Journal of Genomics, Vol 2018 (2018)
Background. Compared with the well-studied 5-methylcytosine (m5C) in DNA, the role and topology of epitranscriptome m5C remain insufficiently characterized. Results. Through analyzing transcriptome-wide m5C distribution in human and mouse, we show th
Externí odkaz:
https://doaj.org/article/271b300dce334098acc2ce7c40c02218
Autor:
Subapriya Rajamanickam, Jun Hyoung Park, Panneerdoss Subbarayalu, Santosh Timilsina, Kaitlyn Bates, Pooja Yadav, Saif S. R. Nirzhor, Vijay Eedunuri, Tabrez A. Mohammad, Kwang Hwa Jung, Benjamin Onyeagucha, Nourhan Abdelfattah, Raymond Benevides, Grace Lee, Yidong Chen, Ratna Vadlamudi, Andrew Brenner, Virginia Kaklamani, Ismail Jatoi, John Kuhn, Robert Hromas, Yogesh K. Gupta, Benny A. Kaipparettu, Jack L. Arbiser, Manjeet K. Rao
Publikováno v:
Communications biology. 5(1)
The major limitations of DNA-targeting chemotherapy drugs include life-threatening toxicity, acquired resistance and occurrence of secondary cancers. Here, we report a small molecule, Carbazole Blue (CB), that binds to DNA and inhibits cancer growth
Autor:
Tabrez A. Mohammad, Yi Chen
Publikováno v:
Bio Protoc
Cancer cell lines serve as invaluable model systems for cancer biology research and help in evaluating the efficacy of new therapeutic agents. However, cell line contamination and misidentification have become one of the most pressing problems affect
Autor:
Tabrez A. Mohammad, Subapriya Rajamanickam, Manjeet K. Rao, Benjamin C. Onyeagucha, Sanjay Bansal, Panneerdoss Subbarayalu, Carla Zeballos, Yi Chen, Nourhan Abdelfattah, Vijay Kumar Eedunuri, Ratna K. Vadlamudi, Rosa M. Guzman, Santosh Timilsina
Publikováno v:
Oncotarget
Deregulation of apoptosis is central to cancer progression and a major obstacle to effective treatment. The Bcl-2 gene family members play important roles in the regulation of apoptosis and are frequently altered in cancers. One such member is pro-ap
Autor:
Tabrez A. Mohammad, Suryavathi Viswanadhapalli, Subbarayalu Panneerdoss, Nourhan Abdelfattah, Benjamin C. Onyeagucha, Yi Chen, Michael T. Drake, T. Rajendra Kumar, Kristiina Vuori, Manjeet K. Rao, Santosh Timilsina
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
Phagocytic clearance of apoptotic germ cells by Sertoli cells is vital for germ cell development and differentiation. Here, using a tissue-specific miRNA transgenic mouse model, we show that interaction between miR-471-5p and autophagy member protein
Autor:
X Cui, Santosh Timilsina, Nourhan Abdelfattah, Yi Chen, Th-M Huang, Manjeet K. Rao, Benjamin C. Onyeagucha, Subapriya Rajamanickam, Yi-Wen Huang, Tabrez A. Mohammad, Vijay Kumar Eedunuri, Panneerdoss Subbarayalu, Suryavathi Viswanadhapalli
Publikováno v:
Cancer Research. 77:P1-04
The importance of RNA methylation in biological processes has just begun to emerge. However, our understanding of the role and mechanism by which RNA methylation may play a role in tumorigenesis is unclear. Here, we report that RNA N6-adenosine methy
Publikováno v:
BMC Genomics
BMC Genomics, Vol 20, Iss S1, Pp 17-29 (2019)
BMC Genomics, Vol 20, Iss S1, Pp 17-29 (2019)
Background Cell lines form the cornerstone of cell-based experimentation studies into understanding the underlying mechanisms of normal and disease biology including cancer. However, it is commonly acknowledged that contamination of cell lines is a p