Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tabea L. Stephan"'
Autor:
Avinash Thakur, Kwangjin Park, Rebecca Cullum, Bettina M. Fuglerud, Mina Khoshnoodi, Sibyl Drissler, Tabea L. Stephan, Jeremy Lotto, Donghwan Kim, Frank J. Gonzalez, Pamela A. Hoodless
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Hepatocyte nuclear factor 4A (HNF4A/NR2a1), a transcriptional regulator of hepatocyte identity, controls genes that are crucial for liver functions, primarily through binding to enhancers. In mammalian cells, active and primed enhancers are
Externí odkaz:
https://doaj.org/article/509818b666a44a0e9f65dd70f8d00e81
Publikováno v:
Nature Reviews Gastroenterology & Hepatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4449ae1af6ca02ecdea855a56bb605b
https://doi.org/10.1038/s41575-023-00775-2
https://doi.org/10.1038/s41575-023-00775-2
Autor:
Bettina M Fuglerud, Sibyl Drissler, Jeremy Lotto, Tabea L Stephan, Avinash Thakur, Rebecca Cullum, Pamela A Hoodless
Publikováno v:
Nucleic acids research. 50(15)
The transcription factor SOX9 is activated at the onset of endothelial-to-mesenchymal transition (EndMT) during embryonic development and in pathological conditions. Its roles in regulating these processes, however, are not clear. Using human umbilic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141f9168c20a0f88fcb5603a00da2d0d
https://pubmed.ncbi.nlm.nih.gov/35904801
https://pubmed.ncbi.nlm.nih.gov/35904801
Autor:
Tabea L. Stephan, Sibyl Drissler, Pamela A. Hoodless, Stephanie A. Campbell, Jeremy Lotto, Rebecca Cullum
Publikováno v:
Development. 148
Liver development is controlled by key signals and transcription factors that drive cell proliferation, migration, differentiation and functional maturation. In the adult liver, cell maturity can be perturbed by genetic and environmental factors that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339879fb2e920030f0f58a5ace0e3c9b
https://doi.org/10.1242/dev.199814
https://doi.org/10.1242/dev.199814
Autor:
Tabea L. Stephan, Jocelyn Bégin, Ben Vanderkruk, Cassandra L. McDonald, Stephanie A. Campbell, Brad G. Hoffman
Publikováno v:
Diabetes. 70(11)
SummaryDuring pancreas development, endocrine progenitors differentiate into the islet-cell subtypes, which undergo further functional maturation in postnatal islet development. In islet β-cells, genes involved in glucose-stimulated insulin secretio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8968f59b142f61669741a33c7c8c4166
https://pubmed.ncbi.nlm.nih.gov/34376477
https://pubmed.ncbi.nlm.nih.gov/34376477
Autor:
Tabea L. Stephan, Bettina M. Fuglerud, Sibyl Drissler, Pamela A. Hoodless, Rebecca Cullum, Avinash Thakur, Jeremy Lotto
The transcription factor SOX9 is expressed in multiple tissues during embryogenesis and directs developmental processes. SOX9 is activated upon endothelial-to-mesenchymal transition (EndMT) in the developing heart, but its role in regulating this pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff8d7593e243307db2cd2c07d083815
https://doi.org/10.1101/2020.09.11.293993
https://doi.org/10.1101/2020.09.11.293993
Autor:
Vaishali Moudgil, Jung-Chien Cheng, Wei Wei, Frank J. Gonzalez, Jeremy Lotto, Evan Y. Wang, Bettina M. Fuglerud, Misha Bilenky, Pamela A. Hoodless, Jasper Wong, Colum P. Walsh, Donghwan Kim, Shu Huei Tsai, Mohammad M. Karimi, Nafeel Ahmed, Matthew Mingay, Martin Hirst, Tabea L. Stephan, Rebecca Cullum, Avinash Thakur
Publikováno v:
Hepatology
Cell-fate determination is influenced by interactions between master transcription factors (TFs) and cis-regulatory elements. Hepatocyte nuclear factor 4 alpha (HNF4A), a liver-enriched TF, acts as a master controller in specification of hepatic prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40fe95b164fd803d4f80070c2def05bc
https://pubmed.ncbi.nlm.nih.gov/30933372
https://pubmed.ncbi.nlm.nih.gov/30933372