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pro vyhledávání: '"Tabbetha J Bohac"'
Autor:
Hannah Valentino, David A. Korasick, Tabbetha J. Bohac, Justin A. Shapiro, Timothy A. Wencewicz, John J. Tanner, Pablo Sobrado
Publikováno v:
ACS Omega, Vol 6, Iss 28, Pp 18537-18547 (2021)
Externí odkaz:
https://doaj.org/article/43a20f12ab4e4abea5c5c7c513e7d5df
Autor:
John J. Tanner, Justin A. Shapiro, Timothy A. Wencewicz, David A. Korasick, Hannah Valentino, Tabbetha J Bohac, Pablo Sobrado
Publikováno v:
ACS Omega, Vol 6, Iss 28, Pp 18537-18547 (2021)
ACS Omega
ACS Omega
Acinetobacter baumannii is an opportunistic pathogen with a high mortality rate due to multi-drug-resistant strains. The synthesis and uptake of the iron-chelating siderophores acinetobactin (Acb) and preacinetobactin (pre-Acb) have been shown to be
Publikováno v:
ACS Infectious Diseases. 7:2138-2151
Many pathogenic bacteria biosynthesize and excrete small molecule metallophores, known as siderophores, that are used to extract ferric iron from host sources to satisfy nutritional need. Native siderophores are often structurally complex multidentat
Publikováno v:
ACS infectious diseases. 7(8)
Many pathogenic bacteria biosynthesize and excrete small molecule metallophores, known as siderophores, that are used to extract ferric iron from host sources to satisfy nutritional need. Native siderophores are often structurally complex multidentat
Autor:
Justin A. Shapiro, Daniel Bailey, Tabbetha J Bohac, Timothy A. Wencewicz, Daryl Giblin, Andrew M. Gulick
Publikováno v:
Biochemistry. 57:6653-6661
The critical role that iron plays in many biochemical processes has led to an elaborate battle between bacterial pathogens and their hosts to acquire and withhold this critical nutrient. Exploitation of iron nutritional immunity is being increasingly
Publikováno v:
ACS Infectious Diseases. 3:802-806
The emergence of multidrug resistant (MDR) Gram-negative bacterial pathogens has raised global concern. Nontraditional therapeutic strategies, including antivirulence approaches, are gaining traction as a means of applying less selective pressure for
Publikováno v:
ACS chemical biology. 14(4)
Environmental and pathogenic microbes produce siderophores as small iron-binding molecules to scavenge iron from natural environments. It is common for microbes to produce multiple siderophores to gain a competitive edge in mixed microbial environmen