Zobrazeno 1 - 10
of 569
pro vyhledávání: '"TYRO3"'
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Clinical trials and studies have implicated that E3 ubiquitin ligase BTBD3 (BTB Domain Containing 3) is a cancer-associated gene. However, the role and underlying mechanism of BTBD3 in colorectal cancer (CRC) is not fully understood yet. Her
Externí odkaz:
https://doaj.org/article/8143ce00dfa740c6aa6598e2fee6d129
Publikováno v:
Kidney Diseases, Pp 1-9 (2024)
Background: Podocyte loss occurs in both primary and secondary glomerular diseases, leading to the progression of kidney disease. A large body of evidence suggests that apoptosis and detachment are the mechanisms mediating the reduction in podocyte n
Externí odkaz:
https://doaj.org/article/72ecd1bb7ddc4a38918a43c8a2d1864f
Akademický článek
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Publikováno v:
Journal of Inflammation Research, Vol Volume 16, Pp 4845-4855 (2023)
Yandan Zhou,1 Zhili Feng,2,3 Jie Wen,2,3 Chi Yang,2,3 Qiancheng Jing2,3 1Changsha Aier Eye Hospital, Aier Eye Hospital Group, Changsha, Hunan, People’s Republic of China; 2Department of Otolaryngology Head and Neck Surgery, the Affiliated Changsha
Externí odkaz:
https://doaj.org/article/716055437a4049b79668ec5b2b8285c5
Autor:
Seyma Demirsoy, Ha Tran, Joseph Liu, Yunzhan Li, Shengyu Yang, Dawit Aregawi, Michael J. Glantz, Naduparambil K. Jacob, Vonn Walter, Todd D. Schell, Inan Olmez
Publikováno v:
Cancers, Vol 16, Iss 12, p 2253 (2024)
Triple-negative breast cancer (TNBC) is the most aggressive subtype with high metastasis and mortality rates. Given the lack of actionable targets such as ER and HER2, TNBC still remains an unmet therapeutic challenge. Despite harboring high CDK4/6 e
Externí odkaz:
https://doaj.org/article/dfee0870155b426398ea4430579653d4
Autor:
Anne L. Prieto, Cary Lai
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3369 (2024)
The TAMs are a subfamily of receptor tyrosine kinases (RTKs) comprised of three members, Tyro3, Axl and Mer. Evidence in support of the existence of this subfamily emerged from a screen for novel RTKs performed in the laboratory of Dr. Greg Lemke in
Externí odkaz:
https://doaj.org/article/827b82b407514de08b4f38558b19037a
Autor:
Varsha Gadiyar, Gopi Patel, Jesse Chen, Dominico Vigil, Nan Ji, Veronica Campbell, Kirti Sharma, Yatao Shi, Matthew M. Weiss, Raymond B. Birge, Viralkumar Davra
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
TAM receptors (TYRO3, AXL, and MERTK) comprise a family of homologous receptor tyrosine kinases (RTK) that are expressed across a range of liquid and solid tumors where they contribute to both oncogenic signaling to promote tumor proliferation and su
Externí odkaz:
https://doaj.org/article/388b5ce7ffc844c99da2b49db324d5dc
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 233 (2023)
The TAM (TYRO3, MERTK, and AXL) family of receptor tyrosine kinases are pleiotropic regulators of adult tissue homeostasis maintaining organ integrity and self-renewal. Disruption of their homeostatic balance fosters pathological conditions like auto
Externí odkaz:
https://doaj.org/article/d13a460427fb4a71a63a357f92d9316f
Akademický článek
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Autor:
Kazushi Hara, Yosuke Horikoshi, Masaki Morimoto, Kazuhiro Nakaso, Teppei Sunaguchi, Tatsuyuki Kurashiki, Yuji Nakayama, Takehiko Hanaki, Manabu Yamamoto, Teruhisa Sakamoto, Yoshiyuki Fujiwara, Tatsuya Matsura
Publikováno v:
Translational Oncology, Vol 28, Iss , Pp 101608- (2023)
Pancreatic cancer (PC) is an aggressive malignancy with few treatment options, and improved treatment strategies are urgently required. TYRO3, a member of the TAM receptor tyrosine kinase family, is a known oncogene; however, the relationship between
Externí odkaz:
https://doaj.org/article/5800b524c0de4011b462ec109bba691c