Zobrazeno 1 - 10
of 1 809
pro vyhledávání: '"TYPE I IFN"'
Autor:
Jianjun Feng, Xinwei Peng, Peng Lin, Yilei Wang, Ziping Zhang, Yuankai Xu, Pengfei Zou, Xiaojian Lai, Pengyun Chen, Tianyu Wang
Publikováno v:
Aquaculture and Fisheries, Vol 9, Iss 6, Pp 908-920 (2024)
IKKε is an IκB kinase participating in the control of NF-κB and type I IFN signal pathways in mammals. However, the function of IKKε in regulating immune response is largely unknown in teleost. Herein, an IKKε homologue named AjIKKε was charact
Externí odkaz:
https://doaj.org/article/e4c42fe394144d04b97d7ec7e84fddf7
Autor:
Min Ho Kim, Ashan Subasinghe, Yongkwan Kim, Hyeok-Il Kwon, Yehjin Cho, Kiramage Chathuranga, Ji-Won Cha, Ji-Yoon Moon, Ji-Hyeon Hong, Jin Kim, Seung-Chul Lee, Niranjan Dodantenna, Nuwan Gamage, W. A. Gayan Chathuranga, Yeonji Kim, In-Joong Yoon, Joo Young Lee, In Pil Mo, Weonhwa Jheong, Sung-Sik Yoo, Jong-Soo Lee
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
African swine fever (ASF), a contagious and lethal haemorrhagic disease of domestic pigs and wild boars, poses a significant threat to the global pig industry. Although experimental vaccine candidates derived from naturally attenuated, genetically en
Externí odkaz:
https://doaj.org/article/50301f8d82c34cb4a269715b8323b9ed
Autor:
Theresa Neuper, Tobias Frauenlob, Hieu-Hoa Dang, Peter W. Krenn, Gernot Posselt, Christof Regl, Nikolaus Fortelny, Veronika Schäpertöns, Michael S. Unger, Gunda Üblagger, Daniel Neureiter, Iris Mühlbacher, Michael Weitzendorfer, Franz Singhartinger, Klaus Emmanuel, Christian G. Huber, Silja Wessler, Fritz Aberger, Jutta Horejs-Hoeck
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Sophisticated immune evasion strategies enable Helicobacter pylori (H. pylori) to colonize the gastric mucosa of approximately half of the world’s population. Persistent infection and the resulting chronic inflammation are a major cause of gastric
Externí odkaz:
https://doaj.org/article/71409594e0d44f3793c2a852288917da
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
A variety of animals can be infected by encephalomyocarditis virus (EMCV). EMCV is the established causative agent of myocarditis and encephalitis in some animals. EMCV causes high fatality in suckling and weaning piglets, making pigs the most suscep
Externí odkaz:
https://doaj.org/article/0acf382eed274435b057d9797278aadc
Autor:
Saeko Yamada, Yasuo Nagafuchi, Mamiko Yamada, Hisato Suzuki, Bunki Natsumoto, Mineto Ota, Ikuo Takazawa, Hiroaki Hatano, Masanori Kono, Hiroaki Harada, Hirofumi Shoda, Tomohisa Okamura, Kenjiro Kosaki, Keishi Fujio
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIKBKE is a negative regulator of T cell activation and one of the key activators of type I interferon (IFN) and NFκB signaling via non-classical pathways. The upstream single nucleotide polymorphism of IKBKE (rs2297550-G) is a genome-wide
Externí odkaz:
https://doaj.org/article/795e72926e734b94bacef5fe13f5d9b6
Autor:
Zhenfang Yan, Jingying Xie, Zhengyang Hou, Yaxin Zhang, Jiayu Yue, Xiangbo Zhang, Lei Chen, Yanmei Yang, Xiangrong Li, Huixia Li, Ruofei Feng
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Natural immunity is the first defense line of the host immune system, which plays a significant role in combating foreign pathogenic microorganisms. The IFN-β (interferon-beta) signaling pathway, being a typical example of innate immunity,
Externí odkaz:
https://doaj.org/article/5e46383ca2b24e3e97117213ec008fae
Autor:
Huanzhuo Mai, Xing Yang, Yulan Xie, Jie Zhou, Yiru Wei, Tingyan Luo, Jing Yang, Ping Cui, Li Ye, Hao Liang, Jiegang Huang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The close link between HIV-1 infection and the occurrence of pulmonary arterial hypertension (PAH). However, the underlying molecular mechanisms of their interrelation remain unclear. The microarray data of HIV-1 and PAH were downloaded from
Externí odkaz:
https://doaj.org/article/2d5026da433f4e3daafd8e5f7bbf0a4c
Autor:
Wei Fan, Bo Wei, Xuyan Chen, Yi Zhang, Pingping Xiao, Kaiyan Li, Yi qin Zhang, Jinmei Huang, Lin Leng, Richard Bucala
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Objective Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by abnormal activation of the type I interferon (IFN) pathway, which results in tissue inflammation and organ damage. We explored the role of the RhoA GTPas
Externí odkaz:
https://doaj.org/article/99f0d7bfdab2483e9b9996dfe8d98fee
Autor:
Nada S. Alakhras, Christopher A. Moreland, Li Chin Wong, Priyam Raut, Sid Kamalakaran, Yi Wen, Robert W. Siegel, Laurent P. Malherbe
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recombinant adeno-associated virus (AAV) vectors have emerged as the preferred platform for gene therapy of rare human diseases. Despite the clinical promise, host immune responses to AAV vectors and transgene remain a major barrier to the developmen
Externí odkaz:
https://doaj.org/article/5d526ac1f027445c881a5c370ba6217e
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Porcine reproductive and respiratory syndrome (PRRS) is an epidemic animal infectious disease worldwide, causing huge economic losses to the global swine industry. Fas-associated death domain (FADD) was previously reported to be an adaptor protein th
Externí odkaz:
https://doaj.org/article/2bc81eaed1d241c884a4a2053e9ac53e