Zobrazeno 1 - 10
of 411
pro vyhledávání: '"TYMS"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: One of the primary obstacles faced by individuals with advanced colorectal cancer (CRC) is the potential development of acquired chemoresistance as the disease advances. Studies have indicated a direct association between elevated level
Externí odkaz:
https://doaj.org/article/a31bbc1af431457ba87c309b6ee6d65b
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAcute Respiratory Distress Syndrome (ARDS) is a common condition in the intensive care unit (ICU) with a high mortality rate, yet the diagnosis rate remains low. Recent studies have increasingly highlighted the role of aging in the occurren
Externí odkaz:
https://doaj.org/article/091ecb62e28c4074a08a566cef167b77
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTProbiotic roles of Clostridium butyricum (C.B) are involved in regulating disease and cancers, yet the mechanistic basis for these regulatory roles remains largely unknown. Here, we demonstrate that C.B reprograms the proliferation, migration
Externí odkaz:
https://doaj.org/article/448e54892cfb4325b06a6c918e0f2129
Autor:
Elham Khalili, Ali Afgar, Azam Rajabpour, Seyed Hamid Aghaee-Bakhtiari, Khadijeh Jamialahmadi, Ladan Teimoori-Toolabi
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21775- (2023)
Background: Colorectal cancer, is one of most prevalent the cancer in the world. 5-Fluorouracil is a standard chemotherapeutic drug while the acquisition of resistance to 5-Fluorouracil is one of the problems during treatment. In this study, we aimed
Externí odkaz:
https://doaj.org/article/52ce70e8f52a47a1822533010ad7aa01
Autor:
Martín Salamini-Montemurri, Ángel Vizoso-Vázquez, Aida Barreiro-Alonso, Lidia Lorenzo-Catoira, Esther Rodríguez-Belmonte, María-Esperanza Cerdán, Mónica Lamas-Maceiras
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3106 (2024)
Human high-mobility group-B (HMGB) proteins regulate gene expression in prostate cancer (PCa), a leading cause of oncological death in men. Their role in aggressive PCa cancers, which do not respond to hormonal treatment, was analyzed. The effects of
Externí odkaz:
https://doaj.org/article/0ae8899560824978adbad7cc86c9f758
Autor:
Mona Kamal Eldeeb, Mai Maher Abd-Elaziz Shoaib, Esraa Ahmed Abd-Elmonem, Hesham Mahmoud Sayd Saeed, Amira Mohammad Embaby, Ayman Mohamed Farouk, Radwa Mohammed Rashad
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background Breast cancer is considered the leading cause of cancer-related death among Egyptian women (15.41%). One of the common BC risk factors is the genetic factor. One-carbon metabolism is one of the pathways reported to increase BC ris
Externí odkaz:
https://doaj.org/article/45f6e5e598234274be21653d6dcb088d
Akademický článek
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Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and one of the major causes of cancer-related death. Thymidylate synthase (TYMS) catalyzes the methylation of deoxy guanosine to deoxy thymidylate, whi
Externí odkaz:
https://doaj.org/article/b07bd7bb46f149da9801557b78257232
Akademický článek
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Publikováno v:
Journal of Personalized Medicine, Vol 13, Iss 6, p 985 (2023)
Uterine leiomyosarcomas (uLMS) have a poor prognosis and a high percentage of recurrent disease. Bioinformatics has become an integral element in rare cancer studies by overcoming the inability to collect a large enough study population. This study a
Externí odkaz:
https://doaj.org/article/25d1cf1a80dd458591cd520b6d1ddc0d