Zobrazeno 1 - 10
of 3 136
pro vyhledávání: '"TXNIP"'
Autor:
Jinhai Deng, Teng Pan, Dan Wang, Yourae Hong, Zaoqu Liu, Xingang Zhou, Zhengwen An, Lifeng Li, Giovanna Alfano, Gang Li, Luigi Dolcetti, Rachel Evans, Jose M Vicencio, Petra Vlckova, Yue Chen, James Monypenny, Camila Araujo De Carvalho Gomes, Gregory Weitsman, Kenrick Ng, Caitlin McCarthy, Xiaoping Yang, Zedong Hu, Joanna C Porter, Christopher J Tape, Mingzhu Yin, Fengxiang Wei, Manuel Rodriguez-Justo, Jin Zhang, Sabine Tejpar, Richard Beatson, Tony Ng
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2080-2108 (2024)
Abstract Chemotherapy, the standard of care treatment for cancer patients with advanced disease, has been increasingly recognized to activate host immune responses to produce durable outcomes. Here, in colorectal adenocarcinoma (CRC) we identify oxal
Externí odkaz:
https://doaj.org/article/5559931ff7c94961b54686129b587544
Autor:
Shimin Wang, Xiaolin Wang, Changhong Qin, Ce Liang, Wei Li, Ai Ran, Qiang Ma, Xiaojuan Pan, Feifei Yang, Junwu Ren, Bo Huang, Yuying Liu, Yuying Zhang, Haiping Li, Hao Ning, Yan Jiang, Bin Xiao
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-22 (2024)
Abstract Background Gastric cancer (GC) is a prevalent malignant tumor, and the RNA-binding protein polypyrimidine tract-binding protein 1 (PTBP1) has been identified as a crucial factor in various tumor types. Moreover, abnormal autophagy levels hav
Externí odkaz:
https://doaj.org/article/c684e77ecfd64ecdb2eefc67da6dc1c0
Autor:
Julia Jolibois, Alison Domingues, Divina El Hamaoui, Raphaël Awaida, Mathilde Berger-de-Gaillardo, Daniel Guérin, David M Smadja, Perrine Marquet-DeRougé, Isabelle Margaill, Elisa Rossi, Valérie Nivet-Antoine
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background This study explores the potential role of Thioredoxin-interacting protein (TXNIP) silencing in endothelial colony-forming cells (ECFCs) within the scope of age-related comorbidities and impaired vascular repair. We aim to elucidat
Externí odkaz:
https://doaj.org/article/23f9a1a27f634f52abc59e9518de0b30
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Background End-stage and acquired cystic renal disease (ESRD/ACRD) kidneys are characterized by inflammatory remodelling and multiplex renal cell carcinomas (RCC). Eosinophilic vacuolated tumour (EVT) occurs exclusively in ACRD. The aim of t
Externí odkaz:
https://doaj.org/article/3e412ba0f73449a893c7791e0c08c4f8
Autor:
Zheng-Lin Dong, Xin Jiao, Zeng-Guang Wang, Kai Yuan, Yi-Qi Yang, Yao Wang, Yun-Tao Li, Tian-Chang Wang, Tian-You Kan, Jian Wang, Hai-Rong Tao
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-24 (2024)
Abstract Background Intervertebral disc degeneration (IVDD) is a multifaceted condition characterized by heterogeneity, wherein the balance between catabolism and anabolism in the extracellular matrix of nucleus pulposus (NP) cells plays a central ro
Externí odkaz:
https://doaj.org/article/677cbfe15a4e4a319d9e5ee7f698da37
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Diabetes treatment options have improved dramatically over the last 100 years, however, close to 2 million individuals in the U.S. alone live with type 1 diabetes (T1D) and are still dependent on multiple daily insulin injections and/or continuous in
Externí odkaz:
https://doaj.org/article/ce004bc3064d4f66a74eec095e00cff3
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37753- (2024)
Sensorineural hearing loss (SNHL) is the most common type of hearing loss worldwide. The primary mechanism is oxidative injury to the cochlea as a result of oxidative stress. Therefore, exploring antioxidant strategies is particularly important in ad
Externí odkaz:
https://doaj.org/article/f5952591f7f543c5bcb78b182019d4a8
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e38206- (2024)
Abstracts: Objective: Diabetic kidney disease (DKD) is a common complication of diabetes mellitus. The pathophysiological changes in platelet function and the hypercoagulable state associated with DKD are closely linked to inflammatory processes. Poe
Externí odkaz:
https://doaj.org/article/a727e86a3e3f43e09a5267c110982955
Autor:
Tahira Aslam, Amina Arif, Shafia Arshad, Fatima Muccee, Khalil Ahmad, Muhammad Omer Iqbal, Umair Khalil, Suhail Razak, Tayyaba Afsar, Ali Almajwal, Huma Shafique, Maryam Zain
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
IntroductionMedicinal plants like Punica granatum (pomegranate) have traditional uses against diabetes, inflammation and other diseases. The study was initiated to get an insight into the interaction tendency of P. granatum derived compounds with dia
Externí odkaz:
https://doaj.org/article/938de824e863467c803951ba628a6444
Autor:
Guentae Kim, Eun Young Kim, Hyowon Lee, Su-Hyun Shin, Se Hee Lee, Ki-Young Sohn, Jae Wha Kim, Jae Sam Lee
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117269- (2024)
Excessive neutrophil infiltration into the tumor microenvironment (TME) is an important factor that contributes to tumor overgrowth and limited immunotherapy efficacy. Neutrophils activate various receptors involved in tumor progression, while suppre
Externí odkaz:
https://doaj.org/article/b812819782414933bfc89bd62643644b