Zobrazeno 1 - 10
of 2 090
pro vyhledávání: '"TWIST1"'
Autor:
Abdulaziz Alfahed
Publikováno v:
Saudi Journal of Biological Sciences, Vol 31, Iss 8, Pp 103842- (2024)
TWIST1, a basic helix-loop-helix transcription factor with versatile roles in cancer, is frequently deregulated in cancers, through established pathway perturbations. However. the significance of TWIST1 methylation in the deregulation of TWIST1 in ga
Externí odkaz:
https://doaj.org/article/f47c4b3f2fe9463eb1afa795c2c936c4
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract MicroRNAs are small RNA molecules that have a significant role in translational repression and gene silencing through binding to downstream target mRNAs. MiR-762 can stimulate the proliferation and metastasis of various types of cancer. Hipp
Externí odkaz:
https://doaj.org/article/00c3b0c7ea5e434882ec7b00741451fd
Publikováno v:
Molecular Oncology, Vol 18, Iss 3, Pp 517-527 (2024)
TWIST1 (TW) is a pro‐oncogenic basic helix–loop–helix (bHLH) transcription factor and promotes the hallmark features of malignancy (e.g., cell invasion, cancer cell stemness, and treatment resistance), which contribute to poor prognoses of glio
Externí odkaz:
https://doaj.org/article/9e6adc00e2824614969ee219bf8002b8
Publikováno v:
Translational Oncology, Vol 48, Iss , Pp 102063- (2024)
Purpose: The aim of this research was to elucidate the role of miR-34b in cervical cancer progression and the underlying mechanism behind the miR-34b-mediated tumor suppression. The study revealed the role of miR-34b as a senescence inducer and serve
Externí odkaz:
https://doaj.org/article/d1641f8eea7e40539cd38031e0856ef2
Autor:
Ziyan Yan, Jiaojiao Zhu, Yuhao Liu, Zhongqiu Li, Xinxin Liang, Shenghui Zhou, Yifan Hou, Huixi Chen, Lin Zhou, Ping Wang, Xingkun Ao, Shanshan Gao, Xin Huang, Ping‐Kun Zhou, Yongqing Gu
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Introduction Radiation‐induced pulmonary fibrosis (RIPF) is a chronic, progressive, irreversible lung interstitial disease that develops after radiotherapy. Although several previous studies have focused on the mechanism of epithelial–me
Externí odkaz:
https://doaj.org/article/d2752eac8b304b11a1bef51b72c13e9a
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract The abnormal lipid and glucose metabolisms are linked to the metabolic disorders, tumorigenesis, and fibrotic diseases, which attracts the increasing attention to find out the key molecules involved in the lipid and glucose metabolism as the
Externí odkaz:
https://doaj.org/article/53824e2a0af14cc88c85966c49c73c10
Akademický článek
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Autor:
Wenjie Ou, Zhaoxue Qi, Ning Liu, Junzi Zhang, Xuguang Mi, Yuan Song, Yanqiu Fang, Baiying Cui, Junjie Hou, Zhixin Yuan
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background: Ulcerative colitis (UC) is a common and progressive inflammatory bowel disease primarily affecting the colon and rectum. Prolonged inflammation can lead to colitis-associated colorectal cancer (CAC). While the exact cause of UC remains un
Externí odkaz:
https://doaj.org/article/6f553d5db15344d88f6eba4bcca91f8d
Autor:
Hongjiao Li, Yi Wang, Shuang Feng, Kaijing Chang, Xinwen Yu, Fenfang Yang, Haozhe Huang, Yuanbo Wang, Xiang Li, Feng Guan
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Chemoresistance poses a significant impediment to effective treatment strategies for myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Our previous study unveiled that oncogene TWIST1 interacted with DNA methyltransferase 3a
Externí odkaz:
https://doaj.org/article/5a1b2ef9ca984599a29c15dd73d48436
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Overexpression of Twist1, one of the epithelial-mesenchymal transition-transcription factors (EMT-TFs), is associated with hepatocellular carcinoma (HCC) metastasis. Pelitinib is known to be an irreversible epidermal growth factor
Externí odkaz:
https://doaj.org/article/9f23526c301947ffa20828d41f84ec08