Zobrazeno 1 - 10
of 37 940
pro vyhledávání: '"TUMORIGENESIS"'
Autor:
Jiayi Sun, Jinquan Liu, Yudong Hou, Jianheng Bao, Teng Wang, Longbi Liu, Yidan Zhang, Rui Zhong, Zhenxuan Sun, Yan Ye, Jintao Liu
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Breast cancer (BC) is a great clinical challenge because of its aggressiveness and poor prognosis. Zinc Finger Protein 64 (ZFP64), as a transcriptional factor, is responsible for the development and progression of cancers. This st
Externí odkaz:
https://doaj.org/article/91f2c9064e284fb2876d2d961493ca35
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Non-coding RNAs (ncRNAs), including circular RNAs (circRNAs) and long non-coding RNAs (lncRNAs), are unique RNA molecules widely identified in the eukaryotic genome. Their dysregulation has been discovered and played key roles in the pathoge
Externí odkaz:
https://doaj.org/article/22f12223cfbc4ae3ae756242f8ddcf44
Autor:
Ying Peng, Xi-Dai Long
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Long non-coding RNAs (lncRNAs) are a distinct class of RNAs with longer than 200 base pairs that are not translated into proteins. Small Nucleolar RNA Host Gene 3 (SNHG3) is a lncRNA and frequently dysregulated in various human ca
Externí odkaz:
https://doaj.org/article/7cec472a7f464a8fb14a20928ebd6d58
Publikováno v:
World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Pancreatic adenocarcinoma (PAAD) is the most frequent kind of pancreatic cancer (PC). Recent studies suggest that lipid metabolism facilitates tumorigenesis, disease progression, and resistance to therapy by promoting lipid synthe
Externí odkaz:
https://doaj.org/article/2ea145eb7dee46d1b4cb863223b989b3
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract The 2019 outbreak of SARS-CoV-2 has caused a major worldwide health crisis with high rates of morbidity and death. Interestingly, it has also been linked to cancer, which begs the issue of whether it plays a role in carcinogenesis. Recent st
Externí odkaz:
https://doaj.org/article/2930294f41ac417a84c7f0c21f2e3081
Autor:
Zhaokun Li, Jingting Li, Fang Li, Liang Han, Chengqiu Sui, Le Zhou, Daqi Zhang, Yantao Fu, Rui Du, Jiedong Kou, Gianlorenzo Dionigi, Hui Sun, Nan Liang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Objectives To examine the putative functions and mechanisms of lysine crotonylation (Kcr) during the development and progression of papillary thyroid cancer (PTC). Methods Samples of thyroid cancer tissues were collected and subjected to liq
Externí odkaz:
https://doaj.org/article/ceb99ed1ee7e43a8b408d072843e7fff
Autor:
Silvia Sozzi, Isabella Manni, Cristiana Ercolani, Maria Grazia Diodoro, Armando Bartolazzi, Francesco Spallotta, Giulia Piaggio, Laura Monteonofrio, Silvia Soddu, Cinzia Rinaldo, Davide Valente
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) features KRAS mutations in approximately 90% of human cases and excessive stromal response, termed desmoplastic reaction. Oncogenic KRAS drives pancreatic carcinogenesis by acting on both ep
Externí odkaz:
https://doaj.org/article/3c9be5d895a14f8e868aacd7a6796b4d
Autor:
Shuang-Ling Wu, Lin Yang, Changcai Huang, Qing Li, Chunhui Ma, Fang Yuan, Yinglin Zhou, Xiaoyue Wang, Wei-Min Tong, Yamei Niu, Feng Jin
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Background Breast tumorigenesis is a complex and multistep process accompanied by both genetic and epigenetic dysregulation. In contrast to the extensive studies on DNA epigenetic modifications 5-hydroxymethylcytosine (5hmC) and 5-methylcyto
Externí odkaz:
https://doaj.org/article/41144b1c9892407d8819b88828740caf
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract KIF18B is a key member of the kinesin-8 family, involved in regulating various physiological processes such as microtubule length, spindle assembly, and chromosome alignment. This article briefly introduces the structure and physiological fu
Externí odkaz:
https://doaj.org/article/a57912ec319546f8a8efc8d31a582ad4
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-31 (2024)
Abstract The intricate interplay between the host and its microbiota has garnered increasing attention in the past decade. Specifically, the emerging recognition of microorganisms within diverse cancer tissues, previously presumed sterile, has ignite
Externí odkaz:
https://doaj.org/article/86b6c49dcb4c4a9dae522010f4cf55cf