Zobrazeno 1 - 10
of 60 340
pro vyhledávání: '"TUMOR PROGRESSION"'
Autor:
Zhenlong Shao, Shutong Liu, Wenshuang Sun, Xuefen Zhuang, Shusha Yin, Ji Cheng, Xiaohong Xia, Yuning Liao, Jinbao Liu, Hongbiao Huang
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-20 (2024)
Abstract Background Sentrin/SUMO-specific protease 3 (SENP3) is essential to regulate protein stability and function in normal and cancer cells. Nevertheless, its role and action mechanisms in prostate cancer (PCa) remain elusive. Thus, clarification
Externí odkaz:
https://doaj.org/article/ba33d983e5ca4b0e85683ec14ca04953
Publikováno v:
Journal of Advanced Research, Vol 65, Iss , Pp 105-123 (2024)
Background: RNA binding proteins (RBPs) play a role in sorting non-coding RNAs (ncRNAs) into exosomes. These ncRNAs, carried by exosomes, are involved in regulating various aspects of tumor progression, including metastasis, angiogenesis, control of
Externí odkaz:
https://doaj.org/article/6f3c31593cd444af8e2acd425ba76bd4
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 10, Pp 803-812 (2024)
ObjectiveTo explore the role of MAPK4 in cervical squamous cell carcinoma (CSCC) for the identification of candidate prognostic prediction biomarkers and molecular therapeutic targets. MethodsThe TCGA cohort was subjected to Kaplan-Meier survival ana
Externí odkaz:
https://doaj.org/article/fecd07e50ff244aa99b9e46ffb9c8994
Autor:
Yuanci Zhang, Songtao Ji, Ge Miao, Shuya Du, Haojia Wang, Xiaohua Yang, Ang Li, Yuanyuan Lu, Xin Wang, Xiaodi Zhao
Publikováno v:
Cancer Biology & Medicine, Vol 21, Iss 9, Pp 769-783 (2024)
Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related deaths worldwide. Dendritic cells (DCs) constitute a heterogeneous group of antigen-presenting cells that are important for initiating and regulati
Externí odkaz:
https://doaj.org/article/d81026213d9843a4b9b5365391881bfc
Autor:
Qingyu Song, Pengchao Wang, Jingyu Wu, Ming Lu, Qingcheng Xia, Yexin Shi, Zijun Wang, Xiang Ma, Qinghong Zhao
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Chondroitin polymerizing factor (CHPF) has been found to be involved in the development of numerous cancers and correlated with poor prognosis. However, its role in the tumorigenesis and development of colorectal cancer (CRC) rema
Externí odkaz:
https://doaj.org/article/458be184bb5344ea827173a4d8b8d368
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Immunotherapy has emerged as a highly effective treatment for various tumors. However, the variable response rates associated with current immunotherapies often restrict their beneficial impact on a subset of patients. Therefore, more effect
Externí odkaz:
https://doaj.org/article/f17ec0a62e3e40d696122cbf2f925e3d
Autor:
José Roberto Cruz-Lozano, Georgina Hernández-Flores, Pablo Cesar Ortiz-Lazareno, Luis Arturo Palafox-Mariscal, Katia Carolina Vázquez-Ibarra, Karen Lilith González-Martínez, María Martha Villaseñor-García, Alejandro Bravo-Cuellar
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 9, Pp 10140-10159 (2024)
Prostate cancer (PCa) is a common and deadly disease in men. It is often diagnosed at advanced stages, at which point patients are treated mainly with docetaxel (DTX), which is effective but limited by resistance and side effects. Overactivation of t
Externí odkaz:
https://doaj.org/article/162bd2a7b9a54a99ad7a882792b10371
Publikováno v:
Breast Cancer: Targets and Therapy, Vol Volume 16, Pp 631-643 (2024)
Xin Yang,1,* Lei Fan,2,* Jicheng Huang,2 Yongjun Li1 1Peking University Fifth School of Clinical Medicine, Beijing, People’s Republic of China; 2Breast Center, Department of Thyroid-Breast-Hernia Surgery, Department of General Surgery, Beij
Externí odkaz:
https://doaj.org/article/b2095b7c315f43d5beca5808f351333f
Autor:
Katarzyna Bialkowska, Lamyae El Khalki, Priyanka S. Rana, Wei Wang, Daniel J. Lindner, Yvonne Parker, Lucia R. Languino, Dario C. Altieri, Elzbieta Pluskota, Khalid Sossey-Alaoui, Edward F. Plow
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Kindlin-2 is a cytoskeletal adapter protein that is present in many different cell types. By virtue of its interaction with multiple binding partners, Kindlin-2 intercalates into numerous signaling pathways and cytoskeletal nodes. A specific
Externí odkaz:
https://doaj.org/article/5573cad98044439ab462d68666ca541d
Autor:
Guoqiang Wang, Zijuan Zhang, Jiaxing Wang, Lu Kang, Guanmin Zheng, Baoguang Liu, Jiezhi Yang, Yangang Sun, Huahui Zeng, Zhenqiang Zhang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Lung adenocarcinoma (LUAD) is the most common subtypes of NSCLC. However, the therapeutic effects for LUAD are unsatisfactory at current stage, so it is important to find new molecular targets and therapeutic strategies. circRNAs can regulat
Externí odkaz:
https://doaj.org/article/2a32a3c7c229449a91c4c6dac0142e87