Zobrazeno 1 - 10
of 20
pro vyhledávání: '"TUDCA, tauroursodeoxycholic acid"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 973-997 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The functions of the liver and the intestine are closely tied in both physiological and pathologic conditions. The gut microbiota (GM) often cause deleterious effects during hepatic pathogenesis. Autophagy is essential for liver hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5847c5c25a4c55b7146f469ae9e2e369
http://www.sciencedirect.com/science/article/pii/S2352345X20301740
http://www.sciencedirect.com/science/article/pii/S2352345X20301740
Publikováno v:
IBRO Reports
IBRO Reports, Vol 9, Iss, Pp 207-217 (2020)
IBRO Reports, Vol 9, Iss, Pp 207-217 (2020)
Highlights • The expression of HERP is increased after intracerebral hemorrhage in vivo and in vitro. • Intracerebral hemorrhage can induce endoplasmic reticulum stress. • Herp is an endoplasmic reticulum stress associated protein. • HERP pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07062cd00469ff483ba969993a7a7b32
http://europepmc.org/articles/PMC7494608
http://europepmc.org/articles/PMC7494608
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 1, Pp 19-32 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Microbes inhabiting the intestinal tract of humans represent a site for xenobiotic metabolism. The gut microbiome, the collection of microorganisms in the gastrointestinal tract, can alter the metabolic outcome of pharmaceuticals, environmental toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511b159fb05311b8d1af4e8394064073
http://www.sciencedirect.com/science/article/pii/S2211383519309736
http://www.sciencedirect.com/science/article/pii/S2211383519309736
Autor:
Grzych, Guillaume, Chavez-Talavera, Oscar, Descat, Amandine, Thuillier, Dorothee, Verrijken, An, Kouach, Mostafa, Legry, Vanessa, Verkindt, Helene, Raverdy, Violeta, Legendre, Benjamin, Caiazzo, Robert, Van Gaal, Luc, Goossens, Jean-Francois, Paumelle, Rejane, Francque, Sven, Pattou, Francois, Haas, Joel T., Tailleux, Anne, Staels, Bart
Publikováno v:
JHEP Reports Innovation in Hepatology
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100222-(2021)
JHEP Reports Innovation in Hepatology, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports Innovation in Hepatology, Elsevier, 2021, 3 (2), pp.100222. ⟨10.1016/j.jhepr.2020.100222⟩
JHEP Reports
JHEP Reports, Vol 3, Iss 2, Pp 100222-(2021)
Background & Aims Plasma bile acids (BAs) have been extensively studied as pathophysiological actors in non-alcoholic steatohepatitis (NASH). However, results from clinical studies are often complicated by the association of NASH with type 2 diabetes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::74e69ecb4a62b415846d1ee012802a9c
https://www.hal.inserm.fr/inserm-03173334/document
https://www.hal.inserm.fr/inserm-03173334/document
Autor:
Julia Doller, Franziska Gisela Thiel, Frank Ulrich Weiss, Ali A. Aghdassi, M. Wiese, Anika Wilden, Laura L. De Freitas Chama, Markus M. Lerch, Robert Bolsmann, Matthias Sendler, Van Huy Tran, Jana Marielle Modenbach, Juliane Glaubitz, Quang Trung Tran
Publikováno v:
Pancreas
Acute pancreatitis (AP) is one of the most common gastroenterological disorders leading to hospitalization. It has long been debated whether biliary AP, about 30% to 50% of all cases, is induced by bile acids (BAs) when they reach the pancreas via re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78284b0d01817a8b3f76689b03e2ea0
https://pubmed.ncbi.nlm.nih.gov/33370017
https://pubmed.ncbi.nlm.nih.gov/33370017
Autor:
Brandyn D. Henriksbo, Kieran Kwok, Akhilesh K. Tamrakar, Wendy Chi, Yong Chen, Mark Heal, Nicole G. Barra, Kevin P. Foley, Yong Liu, Brittany M. Duggan, Jonathan D. Schertzer
Publikováno v:
The Journal of Biological Chemistry
Obesity associates with inflammation, insulin resistance and higher blood lipids. It is unclear if immune responses facilitate lipolysis separate from hormone or adrenergic signals. We found that an ancient component of ER stress, inositol-requiring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2429737118413a4da08eeea23250a451
https://doi.org/10.1101/2020.04.07.030148
https://doi.org/10.1101/2020.04.07.030148
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 15, Iss, Pp 70-81 (2018)
Molecular Metabolism, Vol 15, Iss, Pp 70-81 (2018)
Background: Sex is one of the most powerful modifiers of disease development. Clear sexual dimorphism exists in cardiometabolic health susceptibility, likely due to differences in sex steroid hormones. Changes in the gut microbiome have been linked w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26b129281e97360a1e8ea4806d3c7e1
https://doi.org/10.1016/j.molmet.2018.05.016
https://doi.org/10.1016/j.molmet.2018.05.016
Publikováno v:
The Journal of Biological Chemistry
Calcium (Ca2+) is an essential mineral of endoplasmic reticulum (ER) luminal biochemistry because of the Ca2+ dependence of ER-resident chaperones charged with folding de novo proteins that transit this cellular compartment. ER Ca2+ depletion reduces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65206358fb6831924833dd1d9b317a77
https://doi.org/10.1016/j.jbc.2021.100779
https://doi.org/10.1016/j.jbc.2021.100779
Autor:
Sven-Bastiaan Haange, Alesia Walker, Xin He, Ilias Lagkouvardos, Philippe Schmitt-Kopplin, Thomas Clavel, Yuwen Liu, Xinxin Ke, Martin von Bergen, Peter C.K. Cheung, Nico Jehmlich
Publikováno v:
Molecular metabolism 22, 96-109 (2019). doi:10.1016/j.molmet.2019.01.012
Molecular Metabolism
Molecular Metabolism, Vol 22, Iss, Pp 96-109 (2019)
Mol. Metab. 22, 96-109 (2019)
Molecular Metabolism
Molecular Metabolism, Vol 22, Iss, Pp 96-109 (2019)
Mol. Metab. 22, 96-109 (2019)
Objective The gut microbiota is an important influencing factor of metabolic health. Although dietary interventions with probiotics, prebiotics, and synbiotics can be effective means to regulate obesity and associated comorbidities, the underlying sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480d65f5f77ce95f7d6bdec48b590afb
https://mediatum.ub.tum.de/doc/1544008/document.pdf
https://mediatum.ub.tum.de/doc/1544008/document.pdf
Autor:
Amanda R. Arnold, Benoit Chassaing
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Food additives, such as emulsifiers, stabilizers, or bulking agents, are present in the Western diet and their consumption is increasing. However, little is known about their potential effects on intestinal homeostasis. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560d28fa2ad0635b5bbc0a559060eb92
https://pubmed.ncbi.nlm.nih.gov/30765332
https://pubmed.ncbi.nlm.nih.gov/30765332