Zobrazeno 1 - 10
of 1 165
pro vyhledávání: '"TSUTOMU SUZUKI"'
Autor:
Yuriko Yamazaki, Tomoka Ito, Seitaro Nakagawa, Takashi Sugihira, Chinami Kurita-Tachibana, Amer E. Villaruz, Kensuke Ishiguro, Barbora Salcman, Shuo Li, Sanami Takada, Naohiro Inohara, Yoko Kusuya, Aki Shibata, Masakazu Tamai, Reika Aoyama, Kanako Inoue, Shota Murata, Kazuyuki Matsushita, Akiko Miyabe, Toshibumi Taniguchi, Hidetoshi Igari, Naruhiko Ishiwada, Masateru Taniguchi, Taka-Aki Nakada, Hiroyuki Matsue, Manabu Fujimoto, Haruka Hishiki, Yoshiteru Osone, Hiromichi Hamada, Naoki Shimojo, Tsutomu Suzuki, Michael Otto, Gabriel Núñez, Hiroki Takahashi, Akiko Takaya, Yuumi Nakamura
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Staphylococcus aureus can cause outbreaks and becomes multi-drug resistant through gene mutations and acquiring resistance genes. However, why S. aureus easily adapts to hospital environments, promoting resistance and recurrent infections, r
Externí odkaz:
https://doaj.org/article/786e7ed982d340fb8bdfc8014ce47951
Autor:
Sunita Maharjan, Howard Gamper, Yuka Yamaki, Thomas Christian, Robert Y. Henley, Nan-Sheng Li, Takeo Suzuki, Tsutomu Suzuki, Joseph A. Piccirilli, Meni Wanunu, Erin Seifert, Douglas C. Wallace, Ya-Ming Hou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Human mitochondrial tRNAs (mt-tRNAs), critical for mitochondrial biogenesis, are frequently associated with pathogenic mutations. These mt-tRNAs have unusual sequence motifs and require post-transcriptional modifications to stabilize their f
Externí odkaz:
https://doaj.org/article/6beaaf5507164908a32932465f77b163
Autor:
Jin Matsuura, Shinichiro Akichika, Fan-Yan Wei, Tsutomu Suzuki, Takahiro Yamamoto, Yuka Watanabe, Leoš Shivaya Valášek, Akitake Mukasa, Kazuhito Tomizawa, Takeshi Chujo
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Human cytoplasmic tRNAs contain dihydrouridine modifications at positions 16 and 17 (D16/D17). The enzyme responsible for D16/D17 formation and its cellular roles remain elusive. Here, we identify DUS1L as the human tRNA D16/D17 writer. DUS1
Externí odkaz:
https://doaj.org/article/62cf225a3782431ea55558721a3f500c
Autor:
Ryota Hidese, Takayuki Ohira, Satsuki Sakakibara, Tsutomu Suzuki, Naoki Shigi, Shinsuke Fujiwara
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Ubiquitin-like proteins (Ubls) in eukaryotes and bacteria mediate sulfur transfer for the biosynthesis of sulfur-containing biomolecules and form conjugates with specific protein targets to regulate their functions. Here, we investigated the
Externí odkaz:
https://doaj.org/article/b08146a13223412686b501f5167a1172
Autor:
Asuteka Nagao, Yui Nakanishi, Yutaro Yamaguchi, Yoshifumi Mishina, Minami Karoji, Takafumi Toya, Tomoya Fujita, Shintaro Iwasaki, Kenjyo Miyauchi, Yuriko Sakaguchi, Tsutomu Suzuki
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract In the early stage of bacterial translation, peptidyl-tRNAs frequently dissociate from the ribosome (pep-tRNA drop-off) and are recycled by peptidyl-tRNA hydrolase. Here, we establish a highly sensitive method for profiling of pep-tRNAs usin
Externí odkaz:
https://doaj.org/article/e9718a618adc4f5782970338975e5fd7
Autor:
Yoshinori Takemura, Yuka Sudo, Tomoya Saeki, Shinji Kurata, Tsutomu Suzuki, Tomohisa Mori, Yasuhito Uezono
Publikováno v:
Journal of Pharmacological Sciences, Vol 149, Iss 3, Pp 85-92 (2022)
Neuropathic pain is refractory to opioid analgesics. Since there are functional linkages between μ-opioid receptors (MOR) and cannabinoid receptors (CBR), the present study was designed to investigate the interactions between MOR and CB1R based on a
Externí odkaz:
https://doaj.org/article/3cd30220daee4df6b6670578cbccf9fd
Autor:
Melvin Pan, Christiane Zorbas, Maki Sugaya, Kensuke Ishiguro, Miki Kato, Miyuki Nishida, Hai-Feng Zhang, Marco M. Candeias, Akimitsu Okamoto, Takamasa Ishikawa, Tomoyoshi Soga, Hiroyuki Aburatani, Juro Sakai, Yoshihiro Matsumura, Tsutomu Suzuki, Christopher G. Proud, Denis L. J. Lafontaine, Tsuyoshi Osawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Small molecules that target RNA Polymerase I inhibit ribosome biogenesis to activate p53 through the nucleolar surveillance response pathway. Here, the authors show that p53 induction by ribosome stress is dependent on extracellular glutamine availab
Externí odkaz:
https://doaj.org/article/5a2c48021da748188909409721466a55
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Stop codon recoding is a unique mechanism for selenoprotein biogenesis. Here, the authors report regulatory systems for selenoprotein expression during skeletal muscle differentiation by regulating A-to-I RNA editing and stop codon recoding.
Externí odkaz:
https://doaj.org/article/093074faa1d241cb97a22366f1c38bb2
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Spliceosomal U6 snRNA is modified by m6A. Here the authors show that m6A modification on U6 snRNA promotes efficient recognition of the splice site through cooperating with U5 snRNA, indicating that U6 snRNA m6A allows the 5’ exon sequence variatio
Externí odkaz:
https://doaj.org/article/98277225bb5c42e7b6e2286282d43c55
Autor:
Takayuki Yamagishi, Shigeru Yamauchi, Kyoko Suzuki, Tsutomu Suzuki, Yasuji Kurimoto, Tsutomu Takayama, Yoichi Sakai
Publikováno v:
Journal of Wood Science, Vol 66, Iss 1, Pp 1-7 (2020)
Abstract Japanese cypress (Chamaecyparis obtusa) wood powder impregnated with Fe3+ ions was carbonized using one-step and two-step procedures, and the iron-loaded charcoal was examined using Mössbauer and Raman spectroscopy to elucidate the physicoc
Externí odkaz:
https://doaj.org/article/03202986548a4d458ea629d6f416d160