Zobrazeno 1 - 10
of 3 602
pro vyhledávání: '"TSPO"'
Autor:
Artem Zatcepin, Johannes Gnörich, Boris-Stephan Rauchmann, Laura M. Bartos, Stephan Wagner, Nicolai Franzmeier, Maura Malpetti, Xianyuan Xiang, Yuan Shi, Samira Parhizkar, Maximilian Grosch, Karin Wind-Mark, Sebastian T. Kunte, Leonie Beyer, Carolin Meyer, Desirée Brösamle, Ann-Christin Wendeln, Collins Osei-Sarpong, Steffanie Heindl, Arthur Liesz, Sophia Stoecklein, Gloria Biechele, Anika Finze, Florian Eckenweber, Simon Lindner, Axel Rominger, Peter Bartenstein, Michael Willem, Sabina Tahirovic, Jochen Herms, Katharina Buerger, Mikael Simons, Christian Haass, Rainer Rupprecht, Markus J. Riemenschneider, Nathalie L. Albert, Marc Beyer, Jonas J. Neher, Lars Paeger, Johannes Levin, Günter U. Höglinger, Robert Perneczky, Sibylle I. Ziegler, Matthias Brendel
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-25 (2024)
Abstract Background Microglial activation is one hallmark of Alzheimer disease (AD) neuropathology but the impact of the regional interplay of microglia cells in the brain is poorly understood. We hypothesized that microglial activation is regionally
Externí odkaz:
https://doaj.org/article/a5bbc5a0c7914c46ad9ff511752e6937
Autor:
Artem Zatcepin, Anna Kopczak, Adrien Holzgreve, Sandra Hein, Andreas Schindler, Marco Duering, Lena Kaiser, Simon Lindner, Martin Schidlowski, Peter Bartenstein, Nathalie Albert, Matthias Brendel, Sibylle I. Ziegler
Publikováno v:
Zeitschrift für Medizinische Physik, Vol 34, Iss 2, Pp 218-230 (2024)
Introduction: Neuroinflammation evaluation after acute ischemic stroke is a promising option for selecting an appropriate post-stroke treatment strategy. To assess neuroinflammation in vivo, translocator protein PET (TSPO PET) can be used. However, t
Externí odkaz:
https://doaj.org/article/99ad1382f4344a14b663f0a534b4d97d
Autor:
Lisa-Marie Brunner, Marco Riebel, Simon Wein, Michael Koller, Florian Zeman, Gunnar Huppertz, Tanja Emmer, Yvonne Eberhardt, Jens Schwarzbach, Rainer Rupprecht, Caroline Nothdurfter
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Recent developments suggest that neurosteroids may achieve rapid antidepressant effects. As such, neurosteroidogenesis mediated by the translocator protein 18 kDa (TSPO) might constitute a promising option for the treatment of dep
Externí odkaz:
https://doaj.org/article/53549c5c19df481095562a8dbce5f087
Autor:
Carla Bianca Luena Victorio, Arun Ganasarajah, Wisna Novera, Joanne Ong, Rasha Msallam, Ann-Marie Chacko
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Zika is a systemic inflammatory disease caused by infection with Zika virus (ZIKV). ZIKV infection in adults is associated with encephalitis marked by elevated expression of pro-inflammatory cytokines and chemokines, as well as increased brain infilt
Externí odkaz:
https://doaj.org/article/53eaa171a4204e599923009432e5478a
Autor:
Lucia Maccioni, Carranza Mellana Michelle, Ludovica Brusaferri, Erica Silvestri, Alessandra Bertoldo, Julia J. Schubert, Maria A. Nettis, Valeria Mondelli, Oliver Howes, Federico E. Turkheimer, Michel Bottlaender, Benedetta Bodini, Bruno Stankoff, Marco L. Loggia, Mattia Veronese
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionRecent evidence suggests the blood-to-brain influx rate (K1) in TSPO PET imaging as a promising biomarker of blood–brain barrier (BBB) permeability alterations commonly associated with peripheral inflammation and heightened immune activ
Externí odkaz:
https://doaj.org/article/760dc5ff829c4c71a2186e6159860f14
Autor:
Hendris Wongso, Ahmad Kurniawan, Yanuar Setiadi, Crhisterra E. Kusumaningrum, Eva M. Widyasari, Teguh H.A. Wibawa, Isa Mahendra, Muhamad B. Febrian, Maula E. Sriyani, Iim Halimah, Isti Daruwati, Rudi Gunawan, Arifudin Achmad, Dwianto H. Nugraha, Ronny Lesmana, Ari S. Nugraha
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 14, Iss 1, Pp 86-104 (2024)
The translocator protein 18-kDa (TSPO) is a mitochondrial membrane protein that is previously identified as the peripheral benzodiazepine receptor (PBR). Furthermore, it plays a significant role in a diverse range of biochemical processes, including
Externí odkaz:
https://doaj.org/article/a93a7b382f674a19a78b00f1f3fb5bf3
Autor:
Gloria Biechele, Boris-Stephan Rauchmann, Daniel Janowitz, Katharina Buerger, Nicolai Franzmeier, Endy Weidinger, Selim Guersel, Sebastian Schuster, Anika Finze, Stefanie Harris, Simon Lindner, Nathalie L. Albert, Christian Wetzel, Rainer Rupprecht, Axel Rominger, Carla Palleis, Sabrina Katzdobler, Lena Burow, Carolin Kurz, Mirlind Zaganjori, Lena-Katharina Trappmann, Oliver Goldhardt, Timo Grimmer, Jan Haeckert, Daniel Keeser, Sophia Stoecklein, Estrella Morenas-Rodriguez, Peter Bartenstein, Johannes Levin, Günter U. Höglinger, Mikael Simons, Robert Perneczky, Matthias Brendel
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background and objectives 18-kDa translocator protein position-emission-tomography (TSPO-PET) imaging emerged for in vivo assessment of neuroinflammation in Alzheimer’s disease (AD) research. Sex and obesity effects on TSPO-PET binding hav
Externí odkaz:
https://doaj.org/article/1204a7a1ca6b4f63bf9f3e18c9bf5978
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