Zobrazeno 1 - 10
of 164
pro vyhledávání: '"TS Zimmerman"'
Publikováno v:
Europe PubMed Central
In 20 patients with acute myocardial infarction (AMI) treated with streptokinase (SK, n = 7), recombinant single-chain tissue plasminogen activator (rt-PA, n = 7) or urokinase (UK, n = 6), the behavior of plasma von Willebrand factor (vWF) was studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7bbe72845027b7fe92d2eb9a4cfc81
https://doi.org/10.1182/blood.v79.1.38.bloodjournal79138
https://doi.org/10.1182/blood.v79.1.38.bloodjournal79138
Publikováno v:
Blood. 63:486-489
Purified human factor VIII procoagulant protein (VIII:C) was treated with purified human activated protein C (APC) and the loss of VIII:C activity correlated with proteolysis of the VIII:C polypeptides. APC proteolyzed all VIII:C polypeptides with mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7b9cb3c3f81c8ad550f3af4ac3df219
https://doi.org/10.1182/blood.v63.2.486.486
https://doi.org/10.1182/blood.v63.2.486.486
Publikováno v:
Blood. 56:712-716
The variability of laboratory findings in von Willebrand's disease (vWd) was evaluated by performing serial studies of bleeding time (BT), factor VIII coagulant activity (VIII:C), factor-VIII-related antigen (VIIIR:Ag) and ristocetin cofactor (VIIIR:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccc7f614dea8305d4636ffd3ad68a275
https://doi.org/10.1182/blood.v56.4.712.bloodjournal564712
https://doi.org/10.1182/blood.v56.4.712.bloodjournal564712
Autor:
G Ciavarella, N Ciavarella, S Antoncecchi, D De Mattia, P Ranieri, J Dent, TS Zimmerman, ZM Ruggeri
Publikováno v:
Blood. 66:1423-1429
In Type I von Willebrand disease, the whole series of von Willebrand factor (vWF) multimers is present in plasma, but all are decreased in quantity. No structural abnormality of individual multimers has been demonstrated so far in these patients. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc4a10e38968287f309f1f3b43c511f
https://doi.org/10.1182/blood.v66.6.1423.1423
https://doi.org/10.1182/blood.v66.6.1423.1423
Publikováno v:
Blood. 71:65-70
When normal volunteers or patients with type I von Willebrand disease (VWD) are given desmopressin (DDAVP), a set of larger-than-normal (supranormal) von Willebrand factor (VWF) multimers, similar to those present in VWF-containing cells such as plat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bbbedbfc95e5ba68507bc556e02228e
https://doi.org/10.1182/blood.v71.1.65.bloodjournal71165
https://doi.org/10.1182/blood.v71.1.65.bloodjournal71165
Publikováno v:
Blood. 60:1132-1138
The multimeric structure of platelet factor VIII/von Willebrand factor (FVIII/vWF) in cell extracts and in collagen and thrombin releasates has been analyzed by SDS polyacrylamide gel electrophoresis followed by detection with 125I-anti-FVIII/vWF. Pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86370e4733fbfd5c25ecd59ff34adf09
https://doi.org/10.1182/blood.v60.5.1132.bloodjournal6051132
https://doi.org/10.1182/blood.v60.5.1132.bloodjournal6051132
Publikováno v:
Blood. 54:600-606
A previously healthy elderly man with mucocutaneous bleeding was found to have a benign monoclonal IgG gammapathy associated with criteria for severe von Willebrand disease (Factor VIII procoagulant activity, Factor-VIII-related antigen, and ristocet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2e038c810ed32129aef52f0bf9d9b3d
https://doi.org/10.1182/blood.v54.3.600.bloodjournal543600
https://doi.org/10.1182/blood.v54.3.600.bloodjournal543600
Publikováno v:
Blood. 69(5)
We used immunoblotting of purified factor VIII coagulant protein (FVIII) to localize FVIII inhibitor epitopes in 76 inhibitor plasmas to either the 92-kd FVIII polypeptide (and its 54-kd and/or 44-kd thrombin fragments), the 80-kd polypeptide (and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8363d217e0ed94e1730fb2dd00fbf8
https://pubmed.ncbi.nlm.nih.gov/2436689
https://pubmed.ncbi.nlm.nih.gov/2436689
Publikováno v:
Blood. 61(4)
Factor VIII procoagulant protein (VIII:C) purified from commercial factor VIII concentrate contained multiple polypeptides ranging in mol wt from 79,000 to 188,000, all of which were removed from solution by a monoclonal anti-VIII:C antibody specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780ec13fe0efafc11c17ada0b91db090
https://pubmed.ncbi.nlm.nih.gov/6403080
https://pubmed.ncbi.nlm.nih.gov/6403080
Publikováno v:
Blood. 66(2)
Type IIB von Willebrand disease is characterized by enhanced ristocetin- induced platelet aggregation and absence of large von Willebrand factor multimers from plasma. An alteration of the von Willebrand factor molecule resulting in increased reactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1c10fd3308957d91216d2943304a73
https://pubmed.ncbi.nlm.nih.gov/3926021
https://pubmed.ncbi.nlm.nih.gov/3926021