Zobrazeno 1 - 10
of 4 592
pro vyhledávání: '"TRPV4"'
Autor:
Yicheng Liu, Xiaobing Yao, Wenjun Zhao, Jin Xu, Haiyan Zhang, Ting Huang, Chuang Wu, Jiajia Yang, Cheng Tang, Qianqian Ye, Weiye Hu, Qingming Wang
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Transient receptor potential (TRP) channels are involved in the development and progression of tumors. However, their role in colorectal cancer (CRC) remains unclear, and this study aims to investigate the role of TRP-related gene
Externí odkaz:
https://doaj.org/article/7b646758bdd04195a97cda41ef7a680c
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract The success of lung transplantation is limited by the high rate of primary graft dysfunction due to ischemia-reperfusion injury (IRI). Lung IRI is characterized by a robust inflammatory response, lung dysfunction, endothelial barrier disrupt
Externí odkaz:
https://doaj.org/article/fbd37829100a471980e44bfbb336bf22
Autor:
Zhenhao Li, Zhian Chen, Yutong Wang, Zhenyuan Li, Huilin Huang, Guodong Shen, Yingxin Ren, Xinyuan Mao, Weisheng Wang, Jinzhou Ou, Liwei Lin, Jinlin Zhou, Weihong Guo, Guoxin Li, Yu-Jing Lu, Yanfeng Hu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117134- (2024)
Gastrointestinal cancer is among the most common cancers worldwide. Immune checkpoint inhibitor-based cancer immunotherapy has become an innovative approach in cancer treatment; however, its efficacy in gastrointestinal cancer is limited by the absen
Externí odkaz:
https://doaj.org/article/4b4152e3c88e46839f6ef41642d87109
Autor:
Makiko Kashio, Sandra Derouiche, Reiko U Yoshimoto, Kenji Sano, Jing Lei, Mizuho A Kido, Makoto Tominaga
Publikováno v:
eLife, Vol 13 (2024)
Reports indicate that an interaction between TRPV4 and anoctamin 1 (ANO1) could be widely involved in water efflux of exocrine glands, suggesting that the interaction could play a role in perspiration. In secretory cells of sweat glands present in mo
Externí odkaz:
https://doaj.org/article/d9ce1831558c4c3baaa64943c4ef29c8
Autor:
Junping Fan, Chang Guo, Daohong Liao, Han Ke, Jing Lei, Wenjun Xie, Yuliang Tang, Makoto Tominaga, Zhuo Huang, Xiaoguang Lei
Publikováno v:
Advanced Science, Vol 11, Iss 25, Pp n/a-n/a (2024)
Abstract The nonselective calcium‐permeable Transient Receptor Potential Cation Channel Subfamily V Member4 (TRPV4) channel regulates various physiological activities. Dysfunction of TRPV4 is linked to many severe diseases, including edema, pain, g
Externí odkaz:
https://doaj.org/article/2fc8028f0c104a9b845bdd1c9c58a9e8
Autor:
Kärki Tytti, Koskimäki Sanna, Guenther Carla, Pirhonen Jonatan, Rajakylä Kaisa, Tojkander Sari
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Biophysical cues from the cell microenvironment are detected by mechanosensitive components at the cell surface. Such machineries convert physical information into biochemical signaling cascades within cells, subsequently leading to various
Externí odkaz:
https://doaj.org/article/75dfadc8d63f4735a6b8f11dbd6f09fd
Inflammation-induced TRPV4 channels exacerbate blood–brain barrier dysfunction in multiple sclerosis
Autor:
Cathrin E. Hansen, Alwin Kamermans, Kevin Mol, Kristina Berve, Carla Rodriguez-Mogeda, Wing Ka Fung, Bert van het Hof, Ruud D. Fontijn, Susanne M. A. van der Pol, Laura Michalick, Wolfgang M. Kuebler, Boyd Kenkhuis, Willeke van Roon-Mom, Wolfgang Liedtke, Britta Engelhardt, Gijs Kooij, Maarten E. Witte, Helga E. de Vries
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Blood–brain barrier (BBB) dysfunction and immune cell migration into the central nervous system (CNS) are pathogenic drivers of multiple sclerosis (MS). Ways to reinstate BBB function and subsequently limit neuroinflammation pre
Externí odkaz:
https://doaj.org/article/20142c75d08c47bfb64eb7ea8bb2e9c3
Autor:
Liu Xin, Bi Yanlong
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 2, Pp 225-229 (2024)
Transient receptor potential vanilloid receptor 4(TRPV4)is a non-selective cation channel responsible for sensing changes in cell swelling, temperature, mechanical stretch, shear stress and osmotic pressure by regulating transmembrane calcium signali
Externí odkaz:
https://doaj.org/article/0a7680a34acc4da0aef3e0c40d71325e
Publikováno v:
Channels, Vol 18, Iss 1 (2024)
ABSTRACTThe members of the superfamily of Transient Receptor Potential (TRP) ion channels are physiologically important molecules that have been studied for many years and are still being intensively researched. Among the vanilloid TRP subfamily, the
Externí odkaz:
https://doaj.org/article/e44d19c2f44647f1b0878a2f23c29dde