Immune Checkpoint Inhibitor Colitis: Resident Memory Unleashed

Autor: Michael Dougan

Publikováno v: Gastroenterology

Background & Aims The pathogenesis of immune checkpoint inhibitor (ICI)–colitis remains incompletely understood. We sought to identify key cellular drivers of ICI-colitis and their similarities to idiopathic ulcerative colitis, and to determine pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d508777d919774e7906b97c8d1b115cf
https://doi.org/10.1053/j.gastro.2021.07.007

Disturbed Yin–Yang balance: stress increases the susceptibility to primary and recurrent infections of herpes simplex virus type 1

Autor: Wen Li, Hiroshi Kurihara, Chang Yan, Zhuo Luo, Rong-Rong He, Yi-Fang Li, Robert Dallmann, Xue Li

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 383-398 (2020)

Herpes simplex virus type 1 (HSV-1), a neurotropic herpes virus, is able to establish a lifelong latent infection in the human host. Following primary replication in mucosal epithelial cells, the virus can enter sensory neurons innervating peripheral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72e8bd4a9163466778ab2c0a48ebad5d
https://doi.org/10.1016/j.apsb.2019.06.005

Homeostatic Function and Inflammatory Activation of Ileal CD8

Autor: Lisanne, Lutter, Britt, Roosenboom, Eelco C, Brand, José J, Ter Linde, Bas, Oldenburg, Ellen G, van Lochem, Carmen S, Horjus Talabur Horje, Femke, van Wijk

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Tissue-resident memory T (Trm) cells, both of the CD4 and CD8 lineage, have been implicated in disease flares in inflammatory bowel disease. However, data are conflicting regarding the profile of human CD8+ Trm cells, with studies s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::23ee6f13920597173f824ea4a0dc8fa7
https://pubmed.ncbi.nlm.nih.gov/34224909

Isolation of Lymphocytes from Human Skin and Murine Tissues: A Rapid and Epitope-Preserving Approach.

Autor: Polakova A; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany., Hudemann C; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany., Wiemers F; Department of Gynecology and Obstetrics, Philipps-Universität Marburg, Marburg, Germany., Kadys A; Department of Gynecology and Obstetrics, Philipps-Universität Marburg, Marburg, Germany., Gremke N; Department of Gynecology and Obstetrics, Philipps-Universität Marburg, Marburg, Germany., Lang M; Center for Human Genetics, Philipps-Universität Marburg, Marburg, Germany., Zwiorek L; Department of Gynecology and Obstetrics, Philipps-Universität Marburg, Marburg, Germany., Pfützner W; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany., Hertl M; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany., Möbs C; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany., Zimmer CL; Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.

Publikováno v: JID innovations : skin science from molecules to population health [JID Innov] 2022 Sep 07; Vol. 3 (1), pp. 100155. Date of Electronic Publication: 2022 Sep 07 (Print Publication: 2023).

Disturbed Yin-Yang balance: stress increases the susceptibility to primary and recurrent infections of herpes simplex virus type 1.

Autor: Yan C; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China., Luo Z; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China., Li W; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China., Li X; Institute of Atmospheric Environmental Safety and Pollution Control, Jinan University, Guangzhou 510632, China., Dallmann R; Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK., Kurihara H; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China., Li YF; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China., He RR; Guangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, Jinan University, Guangzhou 510632, China.; International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), School of Pharmacy, Jinan University, Guangzhou 510632, China.

Publikováno v: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2020 Mar; Vol. 10 (3), pp. 383-398. Date of Electronic Publication: 2019 Jun 22.