Zobrazeno 1 - 10
of 687
pro vyhledávání: '"TRIM25"'
Autor:
De Chen Chiang, Beow Keat Yap
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 10, Pp 10745-10761 (2024)
Aberrant expression of TRIM proteins has been correlated with poor prognosis and metastasis in many cancers, with many TRIM proteins acting as key oncogenic factors. TRIM proteins are actively involved in many cancer signaling pathways, such as p53,
Externí odkaz:
https://doaj.org/article/6cff73408f3f4dec82e03762c8446a10
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Background Paclitaxel (PTX) treatment resistance is an important factor leading to poor prognosis in triple-negative breast cancer (TNBC), therefore there is an urgent need to identify new target for combination therapy. Neddylation is a pos
Externí odkaz:
https://doaj.org/article/1a422ba9c77b4f8f88c70135cf74760a
Autor:
Shangting Han, Jiayu Guo, Chenyang Kong, Jun Li, Fangyou Lin, Jiefu Zhu, Tianyu Wang, Qi Chen, Yiting Liu, Haochong Hu, Tao Qiu, Fan Cheng, Jiangqiao Zhou
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 9, Pp n/a-n/a (2024)
ABSTRACT Background Renal ischaemia‒reperfusion injury (IRI) is the primary cause of acute kidney injury (AKI). To date, effective therapies for delaying renal IRI and postponing patient survival remain absent. Ankyrin repeat domain 1 (ANKRD1) has
Externí odkaz:
https://doaj.org/article/498c609bd7c049edb473af7855d6996e
Autor:
Jiyu Zhang, Hongyan Shi, Liaoyuan Zhang, Tingshuai Feng, Jianfei Chen, Xin Zhang, Zhaoyang Ji, Zhaoyang Jing, Xiaoyuan Zhu, Dakai Liu, Xiaoman Yang, Miaomiao Zeng, Da Shi, Li Feng
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-14 (2024)
Abstract Swine acute diarrhea syndrome coronavirus (SADS-CoV), an emerging Alpha-coronavirus, brings huge economic loss in swine industry. Interferons (IFNs) participate in a frontline antiviral defense mechanism triggering the activation of numerous
Externí odkaz:
https://doaj.org/article/77aab75867b14a959000fcb5363ff15a
Autor:
Rezvan Tavakoli, Pooneh Rahimi, Abolfazl Fateh, Mojtaba Hamidi-Fard, Sana Eaybpoosh, Golnaz Bahramali, Seyed Amir Sadeghi, Delaram Doroud, Mohammadreza Aghasadeghi
Publikováno v:
Journal of Infection and Public Health, Vol 17, Iss 8, Pp 102489- (2024)
Background: There are numerous human genes associated with viral infections, and their identification in specific populations can provide suitable therapeutic targets for modulating the host immune system response and better understanding the viral p
Externí odkaz:
https://doaj.org/article/2f752eedde004ef481b175daedcc359e
Autor:
Muhammad Suleman, Abrar Mohammad Sayaf, Abbas Khan, Salman Ali Khan, Norah A. Albekairi, Abdulrahman Alshammari, Abdelali Agouni, Hadi M. Yassine, Sergio Crovella
Publikováno v:
Journal of Infection and Public Health, Vol 17, Iss 7, Pp 102448- (2024)
Background: Influenza A virus causes severe respiratory illnesses, especially in developing nations where most child deaths under 5 occur due to lower respiratory tract infections. The RIG-I protein acts as a sensor for viral dsRNA, triggering interf
Externí odkaz:
https://doaj.org/article/c7e1988a50e1476cb22d124c5fbbe934
Autor:
Yike Chen, Xiaohui Xu, Kaikai Ding, Tianchi Tang, Feng Cai, Haocheng Zhang, Zihang Chen, Yangjian Qi, Zaixiang Fu, Ganggui Zhu, Zhangqi Dou, Jinfang Xu, Gao Chen, Qun Wu, Jianxiong Ji, Jianmin Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background Ubiquitination plays an important role in proliferating and invasive characteristic of glioblastoma (GBM), similar to many other cancers. Tripartite motif 25 (TRIM25) is a member of the TRIM family of proteins, which are involved
Externí odkaz:
https://doaj.org/article/c22c3e93d22845068593e0bde608c5f2
Autor:
Shuang Wu, Xiangyu Dai, Zhipu Zhu, Dianhui Fan, Su Jiang, Yi Dong, Bing Chen, Qi Xie, Zhihui Yao, Qun Li, Rick Francis Thorne, Yao Lu, Hao Gu, Wanglai Hu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 49, Iss , Pp 100971- (2024)
More than half of all cancers demonstrate aberrant c-Myc expression, making this arguably the most important human oncogene. Deregulated long non-coding RNAs (lncRNAs) are also commonly implicated in tumorigenesis, and some limited examples have been
Externí odkaz:
https://doaj.org/article/e594d899c9254c1e8b740f3363cfd418
Autor:
Feifei Yang, Qiang Ma, Bo Huang, Xiaolin Wang, Xiaojuan Pan, Ting Yu, Lingyu Ran, Shan Jiang, Haiping Li, Ye Chen, Yuying Liu, Ce Liang, Junwu Ren, Yuying Zhang, Shimin Wang, Wei Li, Bin Xiao
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Insulin like growth factor II mRNA binding protein 3 (IGF2BP3) is an RNA binding protein with multiple roles in regulation of gene expression at the post-transcriptional level and is implicated in tumorigenesis and progression of
Externí odkaz:
https://doaj.org/article/5aa1e929f50845288c399768a9eb7c02
Publikováno v:
Veterinary Research, Vol 54, Iss 1, Pp 1-13 (2023)
Abstract The innate immune system provides a defense against invading pathogens by inducing various interferon (IFN)-stimulated genes (ISGs). We recently reported that tripartite motif protein 25 (TRIM25), an important ISG, was highly upregulated in
Externí odkaz:
https://doaj.org/article/82fead759a424778b1189d1efe5ef1ba