Zobrazeno 1 - 10
of 795
pro vyhledávání: '"TRF1"'
Autor:
Qing Yin, Tao-Tao Tang, Xiao-Yu Lu, Wei-Jie Ni, Di Yin, Yi-Lin Zhang, Wei Jiang, Yue Zhang, Zuo-Lin Li, Yi Wen, Wei-Hua Gan, Ai-Qing Zhang, Lin-Li Lv, Bin Wang, Bi-Cheng Liu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Chronic kidney disease (CKD) is highly prevalent worldwide, and its global burden is substantial and growing. CKD displays a number of features of accelerated senescence. Tubular cell senescence is a common biological process that
Externí odkaz:
https://doaj.org/article/ff434889c7364d4a959255bc432359f2
Akademický článek
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Autor:
Kexin Zhang, Agata Tarczykowska, Deepesh Kumar Gupta, Devon F. Pendlebury, Cassandra Zuckerman, Jayakrishnan Nandakumar, Hiroki Shibuya
Publikováno v:
Cell Reports, Vol 38, Iss 4, Pp 110289- (2022)
Summary: The meiosis-specific telomere-binding protein TERB1 anchors telomeres to the nuclear envelope and drives chromosome movements for the pairing of homologous chromosomes. TERB1 has an MYB-like DNA-binding (MYB) domain, which is a hallmark of t
Externí odkaz:
https://doaj.org/article/958ac4e3c83749069ab6cf938aa4d281
Autor:
Alvita Vilkeviciute, Greta Gedvilaite, Mantas Banevicius, Loresa Kriauciuniene, Dalia Zaliuniene, Olivija Dobiliene, Rasa Liutkeviciene
Publikováno v:
Cells, Vol 11, Iss 23, p 3847 (2022)
Telomere shortening is well known to be associated with ageing. Age is the most decisive risk factor for age-related macular degeneration (AMD) development. The older the individual, the higher the AMD risk. For this reason, we aimed to find any asso
Externí odkaz:
https://doaj.org/article/b0dfaae2c2c246bea2114bc9e4b0de91
Autor:
Hyuk-Joon Jeon, Jeong Su Oh
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
In eukaryotic chromosomes, the centromere and telomere are two specialized structures that are essential for chromosome stability and segregation. Although centromeres and telomeres often are located in close proximity to form telocentric chromosomes
Externí odkaz:
https://doaj.org/article/4678fa6bdd104a0dbfdd649431261215
Autor:
Leire Bejarano, Giuseppe Bosso, Jessica Louzame, Rosa Serrano, Elena Gómez‐Casero, Jorge Martínez‐Torrecuadrada, Sonia Martínez, Carmen Blanco‐Aparicio, Joaquín Pastor, Maria A Blasco
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 7, Pp 1-21 (2019)
Abstract Telomeres are considered as universal anti‐cancer targets, as telomere maintenance is essential to sustain indefinite cancer growth. Mutations in telomerase, the enzyme that maintains telomeres, are among the most frequently found in cance
Externí odkaz:
https://doaj.org/article/9779bb57d13c41769aa864bea9220f33
Autor:
Matheus Fabiao de Lima, Monique Oliveira Freitas, Mohammad K. Hamedani, Aline Rangel-Pozzo, Xu-Dong Zhu, Sabine Mai
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2299 (2022)
Telomere maintenance is key during cancer development. Malignant cells can either use telomerase or an alternative lengthening of telomere (ALT) pathway to maintain their telomere length. In Hodgkin’s Lymphoma (HL), the presence of telomerase activ
Externí odkaz:
https://doaj.org/article/f1824ce6d4724785ad3b70cf0cd83d72
Autor:
Neal F. Lue
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The telomere protein assemblies in different fungal lineages manifest quite profound structural and functional divergence, implying a high degree of flexibility and adaptability. Previous comparative analyses of fungal telomeres have focused on the r
Externí odkaz:
https://doaj.org/article/d004de416aae4cc1bbbd30bf528fd2ef
Akademický článek
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