Zobrazeno 1 - 10
of 757
pro vyhledávání: '"TRANSLATION EFFICIENCY"'
Autor:
Xuran Zhang, Ke An, Xin Ge, Yuanyuan Sun, Jingyao Wei, Weihong Ren, Han Wang, Yueqin Wang, Yue Du, Lulu He, Ouwen Li, Shaoxuan Zhou, Yong Shi, Tong Ren, Yun-gui Yang, Quancheng Kan, Xin Tian
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-20 (2024)
Abstract Background RNA m5C methylation has been extensively implicated in the occurrence and development of tumors. As the main methyltransferase, NSUN2 plays a crucial regulatory role across diverse tumor types. However, the precise impact of NSUN2
Externí odkaz:
https://doaj.org/article/655f1292da6a4fbd8dc3360438c1b702
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Ex vivo cultivation is a promising strategy for increasing the number of NK cells and enhancing their antitumor activity prior to clinical application. Recent studies show that stimulation with 25KDa branched polyethylenimine (25K
Externí odkaz:
https://doaj.org/article/0452aa39ef7d4e4d933c0eccf48ba0c1
Autor:
Ting Xu, Jing Wang, Yan Wu, Jia‐Yan Wu, Wei‐Cheng Lu, Meng Liu, Su‐Bo Zhang, Dan Xie, Wen‐Jun Xin, Jing‐Dun Xie
Publikováno v:
Advanced Science, Vol 10, Iss 35, Pp n/a-n/a (2023)
Abstract N4‐Acetylcytidine (ac4C), a highly conserved post‐transcriptional machinery with extensive existence for RNA modification, plays versatile roles in various cellular processes and functions. However, the molecular mechanism by which ac4C
Externí odkaz:
https://doaj.org/article/ae10c1d64ec6457c888fd982772f9a6f
Autor:
Marc Weber, Adrià Sogues, Eva Yus, Raul Burgos, Carolina Gallo, Sira Martínez, Maria Lluch‐Senar, Luis Serrano
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 10, Pp n/a-n/a (2023)
Abstract Translation efficiency has been mainly studied by ribosome profiling, which only provides an incomplete picture of translation kinetics. Here, we integrated the absolute quantifications of tRNAs, mRNAs, RNA half‐lives, proteins, and protei
Externí odkaz:
https://doaj.org/article/164836aea25b4702bde2577501844e10
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
RNA accessibility is a useful RNA secondary structural feature for predicting RNA-RNA interactions and translation efficiency in prokaryotes. However, conventional accessibility calculation tools, such as Raccess, are computationally expensive and re
Externí odkaz:
https://doaj.org/article/2f2e9facca7f4dc8ac96b0b16b7df180
Autor:
Heba Farookhi, Xuhua Xia
Publikováno v:
Microorganisms, Vol 12, Iss 4, p 768 (2024)
Different bacterial species have dramatically different generation times, from 20–30 min in Escherichia coli to about two weeks in Mycobacterium leprae. The translation machinery in a cell needs to synthesize all proteins for a new cell in each gen
Externí odkaz:
https://doaj.org/article/e1d8ad1fa2dc449f830db812a8e3f815
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Akademický článek
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Akademický článek
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Autor:
Peter Oelschlaeger
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 132 (2024)
Synonymous mutations result from the degeneracy of the genetic code. Most amino acids are encoded by two or more codons, and mutations that change a codon to another synonymous codon do not change the amino acid in the gene product. Historically, suc
Externí odkaz:
https://doaj.org/article/7706cea1a18e4cbca9a20dfb307c9975