Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery

Autor: Maarten C. Hardenberg, Pietro Sormanni, Michele Perni, Giulia Vecchi, Ryan Limbocker, Julius B. Kirkegaard, Nilumi W. Fernando, Michele Vendruscolo, Thomas Müller, Pavan K. Challa, Christopher M. Dobson, Ellen A. A. Nollen, Tuomas P. J. Knowles, Johnny Habchi, Lianne W.Y. Roode, Kadi L. Saar, Samuel Casford, Mandy Koopman

Publikováno v: Journal of Neuroscience Methods, 306, 57-67. ELSEVIER SCIENCE BV

Background: The nematode worm C. elegans is a model organism widely used for studies of genetics and of human disease. The health and fitness of the worms can be quantified in different ways, such as by measuring their bending frequency, speed or lif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb814c888ef5d3098cb6c299bcd59e0
https://doi.org/10.1016/j.jneumeth.2018.02.005

Hydroximic Acid Derivatives

Publikováno v: Current Pharmaceutical Design. 19(3):309-346

According to the "membrane sensor" hypothesis, the membrane's physical properties and microdomain organization play an initiating role in the heat shock response. Clinical conditions such as cancer, diabetes and neurodegenerative diseases are all cou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::08819a1984bfe5280e60850735fa582a
https://hdl.handle.net/11370/cb98ea9f-41c7-46e0-bdb8-969175be9fd2

Hydroximic Acid Derivatives: Pleiotropic Hsp Co-Inducers Restoring Homeostasis and Robustness

Autor: Gábor Nagy, Burcin Gungor, Laszlo Koranyi, Bianca J. J. M. Brundel, Zsolt Török, Noémi Tóth, Linda Greensmith, Attila Glatz, Kálmán Tory, Ibolya Horváth, Jean Paul Seerden, Stefano Piotto, Simona Concilio, Imre Gombos, Ákos Hunya, Zsuzsanna Literati-Nagy, Tim Crul, Mária Péter, Harm H. Kampinga, Zoltán Szilvássy, Zoltán Berente, Balazs Sumegi, Gábor Balogh, Philip L. Hooper, József Mandl, Irma Kuipers, Federica Campana, Robert H. Henning, Roelien A. M. Meijering, László Vígh, Femke Hoogstra-Berends, Lizette Loen, Pierre Haldimann, Peter Literati-Nagy, Bernadett Kalmar, Mark A. Febbraio, Deli Zhang, André Heeres, Ferenc Gallyas

Publikováno v: Current Pharmaceutical Design, 19(3), 309-346
Current Pharmaceutical Design, 19(3), 309-346. Bentham Science Publishers
Current Pharmaceutical Design, 19(3), 309-346. BENTHAM SCIENCE PUBL LTD
Current Pharmaceutical Design 19 (2013) 3
Scopus-Elsevier

According to the "membrane sensor" hypothesis, the membrane's physical properties and microdomain organization play an initiating role in the heat shock response. Clinical conditions such as cancer, diabetes and neurodegenerative diseases are all cou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65becfc19c472e57faec226bfc74897b
https://doi.org/10.2174/1381612811306030309

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