Thyroid Hormone Receptor α Regulates Autophagy, Mitochondrial Biogenesis, and Fatty Acid Use in Skeletal Muscle

Autor: Xuguang Zhu, Rohit A. Sinha, Jia Pei Ho, Paul M. Yen, Cho Rong Han, Karine Gauthier, Sheue-yann Cheng, Andrea Lim, Jin Zhou

Publikováno v: Endocrinology
Endocrinology, 2021, 162 (9), ⟨10.1210/endocr/bqab112⟩
Endocrinology, Endocrine Society, 2021, 162 (9), ⟨10.1210/endocr/bqab112⟩

Skeletal muscle (SM) weakness occurs in hypothyroidism and resistance to thyroid hormone α (RTHα) syndrome. However, the cell signaling and molecular mechanism(s) underlying muscle weakness under these conditions is not well understood. We thus exa

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https://hal.science/hal-03403597