Zobrazeno 1 - 10
of 733
pro vyhledávání: '"TPX2"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Gallbladder cancer (GBC) is a rare but very aggressive most common digestive tract cancer with a high mortality rate due to delayed diagnosis at the advanced stage. Moreover, GBC progression shows asymptomatic characteristics making it impos
Externí odkaz:
https://doaj.org/article/8d9dbbaaee224b229c27ef10b2cf63a3
Autor:
Carlos Marugán, Natalia Sanz‐Gómez, Beatriz Ortigosa, Ana Monfort‐Vengut, Cristina Bertinetti, Ana Teijo, Marta González, Alicia Alonso de la Vega, María José Lallena, Gema Moreno‐Bueno, Guillermo deCárcer
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1531-1551 (2024)
Chromosomal instability (CIN) is a hallmark of cancer aggressiveness, providing genetic plasticity and tumor heterogeneity that allows the tumor to evolve and adapt to stress conditions. CIN is considered a cancer therapeutic biomarker because health
Externí odkaz:
https://doaj.org/article/3ef5cfa6ef0a445999dcca9dcaa443a0
Autor:
Baojun Chen, Zailong Tian, Guoyong Fu, Ai Zhang, Yaru Sun, Jingjing Wang, Zhaoe Pan, Hongge Li, Daowu Hu, Yingying Xia, Shoupu He, Xiongming Du
Publikováno v:
Journal of Cotton Research, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Background Cotton fiber is a model tissue for studying microtubule-associated proteins (MAPs). The Xklp2 (TPX2) proteins that belong to the novel MAPs member mainly participate in the formation and development of microtubule (MT). However, t
Externí odkaz:
https://doaj.org/article/bea0d0d2e0a448c18eecc23dfe2c385f
Akademický článek
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Autor:
Frontiers Production Office
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/09a3639dbb854124948ce469bf13e324
Publikováno v:
PeerJ, Vol 12, p e17032 (2024)
Purpose This study seeks to identify potential clinical biomarkers for osteoarthritis (OA) using bioinformatics and investigate OA mechanisms through cellular assays. Methods Differentially Expressed Genes (DEGs) from GSE52042 (four OA samples, four
Externí odkaz:
https://doaj.org/article/42f9c5a6f6404341930ad6981122de33
Autor:
Aisha Shabir, Hina Qayoom, Burhan Ul Haq, Adel Abo Mansoor, Adil Abdelrahim, Irshad Ahmad, Abdullah Almilabairy, Fuzail Ahmad, Manzoor Ahmad Mir
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Among women, breast carcinoma is one of the most complex cancers, with one of the highest death rates worldwide. There have been significant improvements in treatment methods, but its early detection still remains an issue to be resolved. This study
Externí odkaz:
https://doaj.org/article/5bd4baa6e36e456c893401f83c528436
Publikováno v:
Cancer Medicine, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract Introduction Approximately 30% of individuals with advanced EC have unsatisfactory prognosis. Evidence suggests that TPX2 is frequently upregulated in malignancies and related to cancer progression. Its role and pathological mechanism in EC
Externí odkaz:
https://doaj.org/article/c7b7533de7e7439ab3043725fe68928a
Autor:
Jiangong XU
Publikováno v:
Chinese Journal of Lung Cancer, Vol 26, Iss 10, Pp 721-731 (2023)
Background and objective Lung adenocarcinoma (LUAD) is a major subtype of lung cancer, and its treatment and diagnosis remain a hot research topic. Targeting protein for Xenopus kinesin-like protein 2 (TPX2) is highly expressed in a variety of cancer
Externí odkaz:
https://doaj.org/article/e0c23eef85e943ada8cf0365a880f89d
Autor:
Hibah Shaath, Radhakrishnan Vishnubalaji, Ramesh Elango, Dinesh Velayutham, Puthen Veettil Jithesh, Nehad M. Alajez
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background While the increased screening, changes in lifestyle, and recent advances in treatment regimen have decreased colorectal cancer (CRC) mortality, metastatic disease and recurrence remains a major clinical challenge. In the era of pr
Externí odkaz:
https://doaj.org/article/5dbea8f2b1d44a91b4733211bcec21d0