Zobrazeno 1 - 10
of 16
pro vyhledávání: '"TPM, transcripts per million"'
Autor:
Simo V. Zhang, Gabor Bartha, Rachel Marty Pyke, Richard Chen, Sean Michael Boyle, Jason Harris, John A. West, Michael Snyder, Sejal Desai, Rena McClory, Charles Abbott, Dattatreya Mellacheruvu, Nick A. Phillips, Steven Dea
Publikováno v:
Mol Cell Proteomics
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Major histocompatibility complex (MHC)-bound peptides that originate from tumor-specific genetic alterations, known as neoantigens, are an important class of anticancer therapeutic targets. Accurately predicting peptide presentation by MHC complexes
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 6229-6239 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 6229-6239 (2021)
Graphical abstract
Introduction The risk of infection with COVID-19 is high in lung adenocarcinoma (LUAD) patients, and there is a dearth of studies on the molecular mechanism underlying the high susceptibility of LUAD patients to COVID-19 from
Introduction The risk of infection with COVID-19 is high in lung adenocarcinoma (LUAD) patients, and there is a dearth of studies on the molecular mechanism underlying the high susceptibility of LUAD patients to COVID-19 from
Autor:
Mete Civelek, Judith Knehr, Samuel W. French, Brie K. Fuqua, Simon T. Hui, Chinweike Ukomadu, Calvin Pan, Kevin Wroblewski, Margarete Mehrabian, Rita M. Cantor, Ashot Asaryan, Joseph Loureiro, Sara G. Haroutunian, Jason Borawski, Brian W. Parks, Aldons J. Lusis, Walter Carbone, Clara E. Magyar, Nicole A. Renaud, Simon W. Beaven, Kara Clerkin, Iina Tuominen, Guglielmo Roma
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 199-220 (2021)
Cellular and molecular gastroenterology and hepatology, vol 11, iss 1
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 11, iss 1
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Liver fibrosis is a multifactorial trait that develops in response to chronic liver injury. Our aim was to characterize the genetic architecture of carbon tetrachloride (CCl4)-induced liver fibrosis using the Hybrid Mouse Diversity
Autor:
Guang-Bo Ge, Saisai Tian, Yili Yang, Ting Shi, Hua-Wu Zeng, Feng Zhang, Jing Zhao, Jian Yang, Shiyi Zhao, Weidong Zhang, Xin Xu, Dong-Zhu Tu, Dong Lu, Yuejuan Zheng
Publikováno v:
Phytomedicine
Background The traditional Chinese medicine (TCM) formula Qing-Fei-Pai-Du decoction (QFPDD) was the most widely used prescription in China's campaign to contain COVID-19, which has exhibited positive effects. However, the underlying mode of action is
Autor:
Nancy Antoine, Lucie Ruiz, Holger Klein, Patrick Gilon, Anne Wojtusciszyn, Fiona M. Gribble, Frank Reimann, Robert Augustin, Bao-Khanh Lai, Bilal Singh, Michael P. Pieper, Eva Gatineau, Nano Rita, Mohammed Bensellam, Pedro Luis Herrera, Birgit Stierstorfer, Firas Khattab, Heeyoung Chae, Lorenzo Piemonti, Davide Brusa, Michael Mark, Eric Mayoux, Christophe Broca
Publikováno v:
Molecular Metabolism
Molecular metabolism, vol. 42, pp. 101071
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 42, pp.101071. ⟨10.1016/j.molmet.2020.101071⟩
Molecular Metabolism (2020) P. 101071
Molecular Metabolism, Vol 42, Iss, Pp 101071-(2020)
Molecular metabolism, vol. 42, pp. 101071
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 42, pp.101071. ⟨10.1016/j.molmet.2020.101071⟩
Molecular Metabolism (2020) P. 101071
Molecular Metabolism, Vol 42, Iss, Pp 101071-(2020)
Objective Sodium-glucose cotransporter 2 (SGLT2) inhibitors (SGLT2i), or gliflozins, are anti-diabetic drugs that lower glycemia by promoting glucosuria, but they also stimulate endogenous glucose and ketone body production. The likely causes of thes
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2851-2859 (2020)
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2851-2859 (2020)
Graphical abstract
Extracellular vesicles (EVs) are complex ecosystems that can be derived from all body cells and circulated in the body fluids. Characterizing the tissue-cellular source contributing to circulating EVs provides biological infor
Extracellular vesicles (EVs) are complex ecosystems that can be derived from all body cells and circulated in the body fluids. Characterizing the tissue-cellular source contributing to circulating EVs provides biological infor
Autor:
Jennifer Landsberg, Dennis Niebel, Emma Grace Bawden, Holger Fröhlich, Judith Sirokay, Glen Kristiansen, Friedrich Bootz, Anne Fröhlich, Sophia Loick, Gonzalo Saavedra, Simon Fietz, Romina Zarbl, Jörn Dietrich, Gerrit H. Gielen, Dimo Dietrich, Eric Diekmann
Publikováno v:
EBioMedicine, Vol 52, Iss, Pp-(2020)
EBioMedicine
EBioMedicine
EBioMedicine 52, 102647 (2020). doi:10.1016/j.ebiom.2020.102647
Published by Elsevier, Amsterdam [u.a.]
Published by Elsevier, Amsterdam [u.a.]
Autor:
R.E.B. Hanna, Kathryn M. Huson, Nicola A.M. Oliver, Philip Best, J.P. Barley, Sam Haldenby, Mark W. Robinson, Tom N. McNeilly, Steve Paterson, Erwan Atcheson, Yongxiang Fang
Publikováno v:
Molecular & Cellular Proteomics : MCP
Paramphistomosis, caused by the rumen fluke, Calicophoron daubneyi, is a parasitic infection of ruminant livestock, which has seen a rapid rise in prevalence throughout Western Europe in recent years. After ingestion of metacercariae (parasite cysts)
Autor:
Marie J. Parsons, Simon Keely
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Diminished forkhead box O3 (FOXO3) function drives inflammation and cancer growth; however, mechanisms fostering these pathobiologies are unclear. Here, we aimed to identify in colon loss of FOXO3-dependent cellular and molecular ch
Autor:
Kathryn F. Tonissen, Maneet Bhatia, Giovanna Di Trapani, Mallory M. King, Kelly L. McGrath, Fenil Shah, F.M. Clarke, Pornpimol Charoentong
Publikováno v:
Redox Biology, Vol 8, Iss C, Pp 68-78 (2016)
Redox Biology
Redox Biology
Metastasis is the most life threatening aspect of breast cancer. It is a multi-step process involving invasion and migration of primary tumor cells with a subsequent colonization of these cells at a secondary location. The aim of the present study wa