Zobrazeno 1 - 10
of 1 480
pro vyhledávání: '"TPH2"'
Autor:
S. E. P. Bruzzone, B. Ozenne, P. M. Fisher, G. Ortega, P. S. Jensen, V. H. Dam, C. Svarer, G. M. Knudsen, K. P. Lesch, V. G. Frokjaer
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Methylation of serotonin-related genes has been proposed as a plausible gene-by-environment link which may mediate environmental stress, depressive and anxiety symptoms. DNA methylation is often measured in blood cells, but little
Externí odkaz:
https://doaj.org/article/0d11b6c981cf49608a29cbb42ecf6bbb
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 280, Iss , Pp 116521- (2024)
The aim of this study is to investigate the role of estrogen receptor β (ERβ) in nonylphenol (NP) - induced depression - like behavior in rats and its impact on the regulation of the TPH2/5-HT pathway. In the in vitro experiment, rat basophilic leu
Externí odkaz:
https://doaj.org/article/6cb7bdf552b74186838fd2d3408ed638
Autor:
Fei Wang, Defan Luo, Jianxiang Chen, Cuiqing Pan, Zhongyao Wang, Housheng Fu, Jianbing Xu, Meng Yang, Shaowei Mo, Liying Zhuang, Weifu Wang
Publikováno v:
BMC Urology, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Background Lifelong premature ejaculation (LPE) is one of the most common ejaculatory dysfunctions in men. The serotonin (5-HT) synthesis rate-limiting enzyme (TPH2) and receptor (HTR1A) in the 5-HT regulatory system may play a key role in t
Externí odkaz:
https://doaj.org/article/08ba26dfcab54f999c118ba163e6b8cf
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-9 (2023)
Abstract Objective To identify DNA methylation and clinical features, and to construct machine learning classifiers to assign the patients with major depressive disorder (MDD) into responders and non-responders after a 2-week treatment into responder
Externí odkaz:
https://doaj.org/article/2d2d60816be04898bfa30435e6a9e89d
Autor:
Zhen Zhang, Zichen Yu, Jinduo Wang, Yifa Yu, Lanxiao Li, Pengjie Sun, Xiaoguang Fan, Qingyang Xu
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Background 5-hydroxytryptophan (5-HTP), the direct biosynthetic precursor of the neurotransmitter 5-hydroxytryptamine, has been shown to have unique efficacy in the treatment of a variety of disorders, including depression, insomnia, and chr
Externí odkaz:
https://doaj.org/article/cffc926aa1f44bda92e80b988d559a1e
Akademický článek
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Autor:
Bin Wang, Haixia Shi, Liyan Ren, Zhigang Miao, Bo Wan, Hao Yang, Xiaotang Fan, Jan-Ake Gustafsson, Miao Sun, Xingshun Xu
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Depression is one of the most common psychiatric diseases. The monoamine transmitter theory suggests that neurotransmitters are involved in the mechanism of depression; however, the regulation on serotonin production is still uncl
Externí odkaz:
https://doaj.org/article/d7968651f2994f359e23849cf6a49512
Autor:
Tingting Tan, Zhi Xu, Chenjie Gao, Tian Shen, Lei Li, Zimu Chen, Lei Chen, Min Xu, Bingwei Chen, Jiacheng Liu, Zhijun Zhang, Yonggui Yuan
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Most antidepressants have been developed on the basis of the monoamine deficiency hypothesis of depression, in which neuronal serotonin (5-HT) plays a key role. 5-HT biosynthesis is regulated by the rate-limiting enzyme tryptophan
Externí odkaz:
https://doaj.org/article/43871279c45e405eaa82cdca7f4be1df
Akademický článek
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Akademický článek
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