Zobrazeno 1 - 10
of 78
pro vyhledávání: '"TP53 polymorphism"'
Autor:
Raushan Kumar Chaudhary, Uday Venkat Mateti, Jayaprakash Shetty, Prakash Patil, Vinay C. Sangamesh, Vijith Vittal Shetty
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Background Cancer of unknown primary (CUP) is an orphan disease generally presented by undifferentiated and aggressive morphological phenotype. The treatment of CUP is solely dependent upon the origin of cancer. Despite extensive diagnostic
Externí odkaz:
https://doaj.org/article/07ae052f82b04c3f860b78d24175f3d4
Publikováno v:
Сахарный диабет, Vol 24, Iss 6, Pp 511-520 (2022)
BACKGROUND: «The vicious circle» of associations of diabetes mellitus (DM) with pancreatic pathology, when pancreatic diseases can initiate DM, and type 2 DM — cause functional and organic pancreatic pathology, determines the search for possible
Externí odkaz:
https://doaj.org/article/ad1d268b985f4e7281faeff250e02af4
Publikováno v:
Сахарный диабет, Vol 24, Iss 6, Pp 511-520 (2022)
BACKGROUND: «The vicious circle» of associations of diabetes mellitus (DM) with pancreatic pathology, when pancreatic diseases can initiate DM, and type 2 DM — cause functional and organic pancreatic pathology, determines the search for possible
Autor:
Philipp B. Staber, Nina Worel, Edit Porpaczy, Oliver Königsbrügge, Johannes Rohrbeck, Philipp Wohlfarth, Ulrich Jaeger, Ingrid Simonitsch-Klupp, Leonhard Müllauer, Werner Rabitsch, Ana-Iris Schiefer, Cathrin Skrabs, Christoph Kornauth
Publikováno v:
Cancers, Vol 13, Iss 5592, p 5592 (2021)
Cancers
Volume 13
Issue 22
Cancers
Volume 13
Issue 22
Refractory/relapsed diffuse large B-cell lymphoma (DLBCL) is associated with poor outcome. The clinical behavior and genetic landscape of DLBCL is heterogeneous and still not fully understood. TP53 mutations in DLBCL have been identified as markers o
Autor:
M.A.C. Smith, M.D.A. Silva, M.S. Cendoroglo, L.R. Ramos, L.M.Q. Araujo, R.W. Labio, R.R. Burbano, E.S. Chen, S.L.M. Payão
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 40, Iss 11, Pp 1465-1472 (2007)
TP53, a tumor suppressor gene, has a critical role in cell cycle, apoptosis and cell senescence and participates in many crucial physiological and pathological processes. Identification of TP53 polymorphism in older people and age-related diseases ma
Externí odkaz:
https://doaj.org/article/02420cd1a39047bfbbcaeb8ece648db2
Autor:
Mahin Ahangar Oskouee, Shohreh Shahmahmoudi, Rakhshandeh Nategh, Heidar-Ali Esmaeili, Firozeh Safaeyan, Maryam Zareinghalame Moghaddam
Publikováno v:
Archives of Breast Cancer, Vol 2, Iss 4 (2015)
Background: The TP53 gene is the most important tumor suppressor gene in humans. The aim of our study was to determine the genotype frequency of three common TP53 polymorphisms (codon 72 BstUI and intron 6 MspI, as well as the intron 3) in a group of
Externí odkaz:
https://doaj.org/article/713a0356ec9041c1af4469e632aa6737
Autor:
Nura Ershad Naznin, Shamima Nasrin Anonna, Abdul Aziz, Sharif Reza, Tahmina Akter, Sarah Jafrin, Mohammad Safiqul Islam
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background A transversion missense polymorphism of the TP53 tumor suppressor gene at the codon 72 codes proline instead of arginine causes an altered p53 protein expression and has been found to be associated with an elevated risk of various cancer;
Autor:
Alsbeih, Ghazi
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Anecdotal epidemiologic observations can provide valuable tools to study various biologic elements in complex diseases such as cancer. Although cervical cancer is one of the most frequent malignancy affecting women in the world, it displays wide geog
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Akademický článek
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