Zobrazeno 1 - 8
of 8
pro vyhledávání: '"TP Jr Loughran"'
Autor:
J Ben-Ezra, J Wright, Robert E. Hutchison, TP Jr Loughran, Aysegul Hasegeli Uner, EC Russell, Teresa C. Gentile
Publikováno v:
Blood. 84:2315-2321
Clonal expansions of CD3+ large granular lymphocytes (LGL) have been classified as T-LGL leukemia. The majority of patients with T-LGL leukemia have a chronic disease (years) manifested often by severe neutropenia, rheumatoid arthritis, and mild-to-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4f49b1b80be8c8912bcca040599acdf
https://doi.org/10.1182/blood.v84.7.2315.bloodjournal8472315
https://doi.org/10.1182/blood.v84.7.2315.bloodjournal8472315
Publikováno v:
Blood. 84:2164-2170
Morbidity and mortality in patients with T large granular lymphocyte (T- LGL) leukemia result from infections acquired during severe neutropenia. Optimum treatment for severe neutropenia remains undefined. We conducted an uncontrolled but prospective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ffc6597154cb6d2c6b5ef4a8df6f61
https://doi.org/10.1182/blood.v84.7.2164.bloodjournal8472164
https://doi.org/10.1182/blood.v84.7.2164.bloodjournal8472164
Publikováno v:
Blood. 78:1282-1285
The activation signals leading to proliferation of normal and leukemic CD3+ large granular lymphocytes (LGL) were studied in vitro. Anti-CD3 monoclonal antibody (MoAb) alone (P less than .01) and recombinant interleukin-2 (IL-2) alone (P less than .0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f10701c9e81643dd0e88ee923c08bc5
https://doi.org/10.1182/blood.v78.5.1282.bloodjournal7851282
https://doi.org/10.1182/blood.v78.5.1282.bloodjournal7851282
Autor:
Keith M. Sullivan, Jean E. Sanders, Mark M. Schubert, George E. Sale, LD Fisher, C. Beckham, Thomas H. Morton, TP Jr Loughran, Howard M. Shulman, Robert P. Witherspoon
Publikováno v:
Blood. 76:228-234
We prospectively evaluated 169 patients with a number of screening studies performed between 71 to 121 days after allogeneic marrow transplantation to detect the development of chronic graft-versus-host disease (GVHD). Group 1 patients (n = 78) were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60acb8bb9b7272f3c1c7f6d177fd772c
https://doi.org/10.1182/blood.v76.1.228.228
https://doi.org/10.1182/blood.v76.1.228.228
Publikováno v:
Blood. 69:72-78
Large granular lymphocyte (LGL) leukemia is a rare disease characterized by clonal expansion of LGL associated with chronic neutropenia, multiple auto-antibodies, and occasionally polyarthritis. We studied cell surface antigen expression and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::457648579c58e2ea7a64b7dd59c68378
https://doi.org/10.1182/blood.v69.1.72.bloodjournal69172
https://doi.org/10.1182/blood.v69.1.72.bloodjournal69172
Publikováno v:
Blood. 72:613-615
We established interleukin-2-(IL-2) dependent cell lines from three patients with large granular lymphocyte (LGL) leukemia. Phenotypic analysis demonstrated retention of the CD3+, CD8+ phenotype that was observed in the original leukemic LGL. Unique
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd6de8c3789f5786554859fbc78c8afa
https://doi.org/10.1182/blood.v72.2.613.bloodjournal722613
https://doi.org/10.1182/blood.v72.2.613.bloodjournal722613
Publikováno v:
Blood. 71:822-824
Ten patients with large granular lymphocyte (LGL) leukemia were studied for rearrangement and expression of T cell receptor (TCR) genes. Eight patients with CD3+ LGL proliferation had unique TCR beta-gene rearrangements, supporting a clonal process.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f22f2e7e95e1c843f1469f7bfe5e40ac
https://doi.org/10.1182/blood.v71.3.822.bloodjournal713822
https://doi.org/10.1182/blood.v71.3.822.bloodjournal713822
Autor:
TP Jr Loughran, G Starkebaum
Publikováno v:
Blood. 69:1786-1786
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43d9875fc52408c2428f9908031121d0
https://doi.org/10.1182/blood.v69.6.1786.bloodjournal6961786
https://doi.org/10.1182/blood.v69.6.1786.bloodjournal6961786