Zobrazeno 1 - 10
of 54
pro vyhledávání: '"TOYOHIKO AOKI"'
Autor:
Terutaka Kodama, Yuko Togashi, Naomi Matsutani, Seiichiro Kurashige, Toyohiko Aoki, Yasuteru Otagiri
Publikováno v:
Fundamental Toxicological Sciences. 9:103-110
Autor:
Yasuteru Otagiri, Terutaka Kodama, Naomi Matsutani, Yuko Togashi, Seiichiro Kurashige, Toyohiko Aoki
Publikováno v:
Fundamental Toxicological Sciences. 8:177-182
Publikováno v:
Fundamental Toxicological Sciences. 8:37-47
Publikováno v:
Fundamental Toxicological Sciences. 8:7-16
Autor:
Seiichiro Kurashige1, Naomi Matsutani1, Toyohiko Aoki2, Terutaka Kodama3, Yasuteru Otagiri1, Yuko Togashi1 yuko_togashi@eapharma.co.jp
Publikováno v:
Journal of Toxicological Sciences. 2023, Vol. 48 Issue 10, p527-534. 8p.
Publikováno v:
Journal of Toxicologic Pathology
Carcinosarcoma is a rare neoplasm composed of malignant epithelial and stromal elements, and, for rats, carcinosarcomas in the kidney have not been reported. In a long-term study to gather background data, we encountered a spontaneous carcinosarcoma
Autor:
Takeshi Masuyama, Seiji Shibata, Shigeru Hisada, Takahiro Narita, Terutaka Kodama, Mami Furuya, Yuichi Mimura, Makiko Kuwagata, Kazuhiro Hayakawa, Toyohiko Aoki, Satoru Hosokawa, Eiji Maki, Shigehiro Tachibana, Motoko Fukui, Masanao Yoshida
Publikováno v:
The Journal of Toxicological Sciences. 38:855-873
The purpose of the present study was to collect background data from repeated dose toxicity studies in Wistar Hannover [Crl:WI(Han)] (hereafter Wistar Han) rats with dosing periods of 4, 13 and 26 weeks from four safety research facilities of pharmac
Autor:
Jiro Sonoda, Yoshikazu Taketa, Aya Goto, Etsuko Ohta, Yuki Seki, Kazuo Tsukidate, Kyoko Nakano, Toyohiko Aoki, Satoru Hosokawa, Kazuhiro Hayakawa, Akira Inomata
Publikováno v:
Journal of Toxicologic Pathology
Maxillary gingivae from male and female Crl:CD(SD) rats at 12, 16, 21, and 34 weeks of age were examined histologically. The incidence of gingivitis was approximately 40%, with no age or sex predilection, and was most frequent between the first and s
Autor:
Chisato Mori, Emiko Kato, Yoshiharu Matsuno, Tetsuya Fukuta, Keiji Uchida, Toyohiko Aoki, Hiroshi Mineshima
Publikováno v:
Journal of Applied Toxicology. 32:98-107
Azole derivatives have teratogenic effects in rodents. In the present study, malformations and their sensitive windows induced by high-dose ketoconazole (KCZ), an azole derivative, without maternal toxicity were investigated. In addition, the malform
Autor:
Yuki Momozawa, Jyoji Yamate, Akira Inomata, Kazuo Tsukidate, Yoshikazu Taketa, Midori Yoshida, Toyohiko Aoki, Satoru Hosokawa, Kazuhiro Hayakawa, Kyoko Nakano, Jiro Sonoda
Publikováno v:
Toxicologic Pathology. 39:372-380
Ethylene glycol monomethyl ether (EGME) is a known reproductive toxicant that induces luteal hypertrophy in rat ovaries. In this study, we characterized the histopathological features of corpora lutea (CL) from EGME–treated rats and compared them w