Zobrazeno 1 - 10
of 465
pro vyhledávání: '"TOSHIO NAKANISHI"'
Autor:
Ayako Chida‐Nagai, Hiroyuki Akagawa, Saori Sawai, Yue‐Jiao Ma, Satoshi Yakuwa, Jun Muneuchi, Kazushi Yasuda, Hirokuni Yamazawa, Toshiyuki Yamamoto, Emi Takakuwa, Utano Tomaru, Yoshiyuki Furutani, Tatsuya Kato, Gen Harada, Kei Inai, Toshio Nakanishi, Atsushi Manabe, Atsuhito Takeda, Zhi‐Cheng Jing
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Peripheral pulmonary stenosis (PPS) is a condition characterized by the narrowing of the pulmonary arteries, which impairs blood flow to the lung. The mechanisms underlying PPS pathogenesis remain unclear. Thus, the aim of this study was t
Externí odkaz:
https://doaj.org/article/a2cb78169263400cbe224421f099250e
Autor:
Shinya Ishii, Aya Sugiyama, Noriaki Ito, Kei Miwata, Yoshihiro Kitahara, Mafumi Okimoto, Akemi Kurisu, Kanon Abe, Hirohito Imada, Tomoyuki Akita, Tatsuhiko Kubo, Akira Nagasawa, Toshio Nakanishi, Toshiro Takafuta, Masao Kuwabara, Junko Tanaka
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Perceived discrimination and work impairment are commonly observed in COVID-19 survivors, but their relationship has not been well understood. We aimed to evaluate the role of discrimination in the development of psychological distress and w
Externí odkaz:
https://doaj.org/article/4ab1d49a47f54c96810ced5ac7353d33
Autor:
Aya Sugiyama, Kei Miwata, Yoshihiro Kitahara, Mafumi Okimoto, Kanon Abe, Bunthen E, Serge Ouoba, Tomoyuki Akita, Naoki Tanimine, Hideki Ohdan, Tatsuhiko Kubo, Akira Nagasawa, Toshio Nakanishi, Toshiro Takafuta, Junko Tanaka
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract This cross-sectional study aimed to investigate the post-acute consequences of COVID-19. We conducted a self-administered questionnaire survey on sequelae, psychological distress (K6), impairments in work performance (WFun), and COVID-19–r
Externí odkaz:
https://doaj.org/article/3f162dd613c14372bdf6598dcd836b2d
Autor:
Nanako Kawaguchi, Antonino Bruno, Prabhakara R. Nagareddy, Toshio Nakanishi, Murugesan V. S. Rajaram, Gaia Spinetti
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/89f6c1a1ba844897a90238d743d83767
Autor:
Nanako Kawaguchi, Toshio Nakanishi
Publikováno v:
Biology, Vol 12, Iss 3, p 468 (2023)
Currently, zebrafish, rodents, canines, and pigs are the primary disease models used in cardiovascular research. In general, larger animals have more physiological similarities to humans, making better disease models. However, they can have restricte
Externí odkaz:
https://doaj.org/article/32ad8661412b496c9fbc8eeed2a4a001
Autor:
Tingting Zhang, Nanako Kawaguchi, Kenji Yoshihara, Emiko Hayama, Yoshiyuki Furutani, Kayoko Kawaguchi, Takeshi Tanaka, Toshio Nakanishi
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background C-X-C chemokine receptor type 4 (CXCR4) may be involved in the development of pulmonary arterial hypertension (PAH). CXCR4 inhibitor AMD3100 was described to have a positive effect on the prevention of pulmonary arterial musculari
Externí odkaz:
https://doaj.org/article/7c21aae104ff49beb3e0244c95b52b67
Autor:
Yu Nakagama, Norihiko Takeda, Seishi Ogawa, Hiroyuki Takeda, Yoshiyuki Furutani, Toshio Nakanishi, Tatsuyuki Sato, Yoichiro Hirata, Akira Oka, Ryo Inuzuka
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 3, Pp n/a-n/a (2020)
Abstract Background Variants in the LZTR1 (leucine‐zipper‐like transcription regulator 1) gene (OMIM #600574) have been reported in recessive Noonan syndrome patients. In vivo evidence from animal models to support its causative role is lacking.
Externí odkaz:
https://doaj.org/article/a35ab36eda294c3c9d21f00b20f0a5de
Autor:
Nanako Kawaguchi, Toshio Nakanishi
Publikováno v:
Biology, Vol 11, Iss 1, p 122 (2022)
Stem cells are used in cardiovascular biology and biomedicine, and research in this field is expanding. Two types of stem cells have been used in research: induced pluripotent and somatic stem cells. Stem cell research in cardiovascular medicine has
Externí odkaz:
https://doaj.org/article/91633b6bc111468296f147084979a4f9
Autor:
Emiko Hayama, Yoshiyuki Furutani, Nanako Kawaguchi, Akiko Seki, Yoji Nagashima, Keisuke Okita, Daiji Takeuchi, Rumiko Matsuoka, Kei Inai, Nobuhisa Hagiwara, Toshio Nakanishi
Publikováno v:
Biology, Vol 10, Iss 10, p 1062 (2021)
The SCN5A R1623Q mutation is one of the most common genetic variants associated with severe congenital long QT syndrome 3 (LQT3) in fetal and neonatal patients. To investigate the properties of the R1623Q mutation, we established an induced pluripote
Externí odkaz:
https://doaj.org/article/2e11d85f1306437cb6a6f913b53ccac6
Autor:
Tingting Zhang, Nanako Kawaguchi, Kunikazu Tsuji, Emiko Hayama, Yoshiyuki Furutani, Hisashi Sugiyama, Toshio Nakanishi
Publikováno v:
Cells, Vol 9, Iss 5, p 1276 (2020)
Previously we reported that silibinin ameliorated pulmonary arterial hypertension (PAH) in rat PAH models, possibly through the suppression of the CXCR4/SDF-1, until the point where PAH became a severe and irreversible condition. To further investiga
Externí odkaz:
https://doaj.org/article/eaacb732253541fcba16c2310c0e42ae