Výsledky vyhledávání - "TOSHIAKI KADOKAWA"

Analgesic Activity of Morphine Suppository in Rats

Autor: Takashi Tan, Atsuko Kita, Toshiaki Kadokawa, Hideo Nakamura

Publikováno v: YAKUGAKU ZASSHI. 110:349-353

Analgesic activity of morphine administered rectally as a suppository was investigated in rats in order to ascertain analgesic activity of morphine suppository. Morphine hydrochloride given rectally as a suppository produced analgesic activity in a d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6135a0c896b1f354c5cdbe51ef4a4125
https://doi.org/10.1248/yakushi1947.110.5_349

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Effects of enoxacin and its combination with 4-biphenylacetate, an active metabolite of fenbufen, on population spikes in rat hippocampal slices

Autor: Toshiaki Kadokawa, Seiji Hori, Tadashi Miyahara, Tsugutaka Ito, Yoshiki Miura, Jingoro Shimada

Publikováno v: Pharmacologytoxicology. 68(3)

The effects of enoxacin, a new quinolone antibacterial agent, and its combination with 4-biphenylacetate (BPA), an active metabolite of the non-steroidal antiinflammatory agent fenbufen, were examined on population spikes induced by electrical stimul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23872677083d8fa01babe6d8d5a0219e
https://pubmed.ncbi.nlm.nih.gov/2057453

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Inhibition of prostaglandin generation in the rabbit brain in-vivo by AD-1590, a non-steroidal antiinflammatory agent with potent antipyretic activity

Autor: Yuichi Yokoyama, Yasuhiro Seto, Hideo Nakamura, Masanao Shimizu, Toshiaki Kadokawa, Satoru Motoyoshi

Publikováno v: Journal of Pharmacy and Pharmacology. 37:894-898

The inhibition of prostaglandin generation by AD-1590 was investigated in the rabbit brain in-vivo. AD-1590 (0ṁ4 mg kg−1 i.v.) markedly prevented both the increases in body temperature and PGE2 level in cerebrospinal fluid (CSF) caused by i.v. in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954856bf33187cd704fe9961c9c20ac8
https://doi.org/10.1111/j.2042-7158.1985.tb04996.x

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Functional Change in the Rat Spinal Cord by Chronic Spinal Transection and Possible Roles of Monoamine Neurons

Autor: Kiyoshi Furukawa, Toshiaki Kadokawa, Tadahiko Karasawa, Tsugutaka Ito, Masanao Shimizu

Publikováno v: Japanese Journal of Pharmacology. 38:243-251

Two types of spinal reflex responses, extensor reflex and ventral root potential, were compared physiologically and pharmacologically in acute and chronic spinal cord transected rats. The recovery curve of the extensor reflex, recorded as evoked elec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c05cc6395fd426d0e6d547554f4017
https://doi.org/10.1254/jjp.38.243

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A correlation between the species differences in anti-inflammatory activity of AD-1590, a non-steroidal anti-inflammatory drug, and its plasma level

Autor: Yuichi Yokoyama, Satoru Motoyoshi, Toshiaki Kadokawa, Hideo Nakamura, Yasuhiro Seto

Publikováno v: Folia Pharmacologica Japonica. 91:393-399

Authors have reported that the oral potency ratio of AD-1590 to indomethacin varies with the animal models employed; the ratio is 4, 2.3 and 31 in the tests of acetic acid-induced vascular permeability (male mice), carrageenan hind paw edema (male ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96eb70f652490622b09b2d5b66e0a81
https://doi.org/10.1254/fpj.91.393

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Effects of Zonisamide (AD-810) on Tungstic Acid Gel-Induced Thalamic Generalized Seizures and Conjugated Estrogen-Induced Cortical Spike-Wave Discharges in Cats

Autor: Misako Hori, Toshiaki Kadokawa, Tsugutaka Ito

Publikováno v: Epilepsia. 27:367-374

Summary: Effects of zonisamide (AD-810, CI-912) were examined on tungstic acid gel-induced thalamic generalized seizures and conjugated estrogen-induced cortical spike-wave discharges in gallamine-immobilized cats. Zonisamide prolonged the interictal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7fdb84e57459790acf29434cf80156
https://doi.org/10.1111/j.1528-1157.1986.tb03555.x

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