Zobrazeno 1 - 10
of 345
pro vyhledávání: '"TOSHIAKI IBA"'
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The mortality rate of sepsis remains high and further increases when complicated by disseminated intravascular coagulation (DIC). Consequently, early detection and appropriate management of DIC will be helpful for the management of sepsis. A
Externí odkaz:
https://doaj.org/article/9f2f36b8163e4f538b35b049db9d6dbe
Autor:
Takaaki Totoki, Hiroyuki Koami, Yuto Makino, Takeshi Wada, Takashi Ito, Kazuma Yamakawa, Toshiaki Iba
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-8 (2024)
Abstract Background Sepsis is a life-threatening condition that affects 49 million people annually. Managing sepsis-associated coagulopathy poses a significant challenge due to its high mortality rates in intensive care. Recent reports suggest that a
Externí odkaz:
https://doaj.org/article/6137daed09444d1dbf592932f5bb0fbc
Autor:
Toshiaki Iba, Kazuma Yamakawa, Yuki Shiko, Ryo Hisamune, Tomoki Tanigawa, Julie Helms, Jerrold H. Levy
Publikováno v:
Journal of Intensive Care, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Background There is no reliable indicator that can assess the treatment effect of anticoagulant therapy for sepsis-associated disseminated intravascular coagulation (DIC) in the short term. The aim of this study is to develop and validate a
Externí odkaz:
https://doaj.org/article/8384f487490447aa98fb7b68a7b675c0
Publikováno v:
Annals of Intensive Care, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Maintaining tissue perfusion in sepsis depends on vascular integrity provided by the endothelial glycocalyx, the critical layer covering the luminal surface of blood vessels. The glycocalyx is composed of proteoglycans, glycosaminoglycans, a
Externí odkaz:
https://doaj.org/article/8b74499186be49db931d88ef78e5a522
Autor:
Takaaki Totoki, Yuto Makino, Kazuma Yamakawa, Hiroyuki Koami, Takeshi Wada, Takashi Ito, Toshiaki Iba
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background Disseminated intravascular coagulation (DIC) syndrome is a highly lethal condition characterized by the complication of multiple organ damage. Although the effects of combined antithrombin (AT) and recombinant thrombomodulin (rTM)
Externí odkaz:
https://doaj.org/article/c75558ad828743fda6ab166dd511e80a
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Disseminated intravascular coagulation (DIC) is a frequent complication in patients with sepsis and is associated with increased mortality. Anticoagulant therapy may be appropriate for certain patients with DIC, particularly those with incre
Externí odkaz:
https://doaj.org/article/4658e1fe4d2e4af3809969e91ff45823
Autor:
Junko Ichikawa, Toshiaki Iba, Ryouta Okazaki, Tomoki Fukuda, Mitsuharu Kodaka, Makiko Komori, Jerrold H. Levy
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract This in vitro study evaluated the potential hemostatic effect of fresh frozen plasma (FFP) ultrafiltration on clotting factors, coagulation parameters, and plasma properties. ABO-specific units of FFP (n = 40) were prepared for the concentra
Externí odkaz:
https://doaj.org/article/f66fc758a7944dd1bc7b72397bbab80f
Publikováno v:
Thrombosis Journal, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Disseminated intravascular coagulation (DIC) is a common and critical complication in sepsis. Antithrombin activity, which is considered a biomarker for disease severity, was measured in septic DIC treated with antithrombin concen
Externí odkaz:
https://doaj.org/article/041856b1648f4f0dbc3750fef8cfb8d5
Publikováno v:
Journal of Intensive Care, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract Background The International Society on Thrombosis and Haemostasis (ISTH) released overt disseminated intravascular coagulation (DIC) diagnostic criteria in 2001. Since then, DIC has been understood as the end-stage consumptive coagulopathy
Externí odkaz:
https://doaj.org/article/c4f4f5c73317408da10f2738fde3bd05
Autor:
Hideo Wada, Kazuo Kawasugi, Goichi Honda, Noriaki Kawano, Toshimasa Uchiyama, Seiji Madoiwa, Naoki Takezako, Kei Suzuki, Yoshinobu Seki, Takayuki Ikezoe, Toshiaki Iba, Kohji Okamoto
Publikováno v:
TH Open, Vol 07, Iss 01, Pp e65-e75 (2023)
Abstract Background Disseminated intravascular coagulation (DIC) is not a homogeneous condition, but rather includes heterogeneous conditions, and its pathophysiology and outcome vary considerably depending on the background. Although anticoagulant
Externí odkaz:
https://doaj.org/article/0fadba14e37e45bf84126d976b253e62