Zobrazeno 1 - 10
of 281
pro vyhledávání: '"TORU KOMATSU"'
Autor:
Honami Echizen, Kenjiro Hanaoka, Kazuhito Shimamoto, Ryota Hibi, Sachiko Toma-Fukai, Hisashi Ohno, Eita Sasaki, Toru Komatsu, Tasuku Ueno, Yukihiro Tsuchiya, Yasuo Watanabe, Takao Otsuka, Hiroaki Saito, Satoru Nagatoishi, Kouhei Tsumoto, Hirotatsu Kojima, Takayoshi Okabe, Toshiyuki Shimizu, Yasuteru Urano
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract D,L-Propargylglycine (PAG) has been widely used as a selective inhibitor to investigate the biological functions of cystathionine γ-lyase (CSE), which catalyzes the formation of reactive sulfur species (RSS). However, PAG also inhibits othe
Externí odkaz:
https://doaj.org/article/90eed93fe0d34640b472dbfd8bff78fa
Autor:
Tatsuya Ukegawa, Toru Komatsu, Mayano Minoda, Takuya Matsumoto, Takumi Iwasaka, Tadahaya Mizuno, Ryo Tachibana, Shingo Sakamoto, Kenjiro Hanaoka, Hiroyuki Kusuhara, Kazufumi Honda, Rikiya Watanabe, Yasuteru Urano
Publikováno v:
Advanced Science, Vol 11, Iss 10, Pp n/a-n/a (2024)
Abstract Single‐molecule enzyme activity assay is a platform that enables the analysis of enzyme activities at single proteoform level. The limitation of the targetable enzymes is the major drawback of the assay, but the general assay platform is r
Externí odkaz:
https://doaj.org/article/a9a6946f5e86432fbac5da93a75bd205
Autor:
Kouichi Yanagi, Toru Komatsu, Yuuta Fujikawa, Hirotatsu Kojima, Takayoshi Okabe, Tetsuo Nagano, Tasuku Ueno, Kenjiro Hanaoka, Yasuteru Urano
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-8 (2023)
Abstract Controlling tumor-specific alterations in metabolic pathways is a useful strategy for treating tumors. The glyoxalase pathway, which metabolizes the toxic electrophile 2-methylglyoxal (MG), is thought to contribute to tumor pathology. We dev
Externí odkaz:
https://doaj.org/article/e9e6082763a849dc8de3ca821b8e7c5f
Autor:
Kazuki Tanaka, Naoki Tanigawa, Isaiah Song, Toru Komatsu, Yugo Kuriki, Yukari Tanaka, Shin Fukudo, Yasuteru Urano, Shinji Fukuda
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Irritable bowel syndrome (IBS) has no clinically accepted biomarkers even though it affects a large number of individuals worldwide. To address this lack of understanding, we evaluated peptidase activity in fecal samples from 35 patients with diarrhe
Externí odkaz:
https://doaj.org/article/ef4008d18cc442d8a13bcc641244efa1
Autor:
Shun Kawashima, Daisuke Yoshida, Takafusa Yoshioka, Akira Ogasawara, Kyohhei Fujita, Masahiro Yanagiya, Masaaki Nagano, Chihiro Konoeda, Haruaki Hino, Kentaro Kitano, Masaaki Sato, Rumi Hino, Ryosuke Kojima, Toru Komatsu, Mako Kamiya, Yasuteru Urano, Jun Nakajima
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Rapid identification of lung-cancer micro-lesions is becoming increasingly important to improve the outcome of surgery by accurately defining the tumor/normal tissue margins and detecting tiny tumors, especially for patients with low lung fu
Externí odkaz:
https://doaj.org/article/848ad2ce193d471e9e7a9570d77bb4de
Autor:
Kazuhisa Hirabayashi, Kenjiro Hanaoka, Takahiro Egawa, Chiaki Kobayashi, Shodai Takahashi, Toru Komatsu, Tasuku Ueno, Takuya Terai, Yuji Ikegaya, Tetsuo Nagano, Yasuteru Urano
Publikováno v:
Data in Brief, Vol 12, Iss C, Pp 351-357 (2017)
In this data article, we described the detailed synthetic procedure and the experimental data for the synthesis of a red-fluorescent probe for calcium ions (Ca2+) with improved water solubility. This Ca2+ red-fluorescent probe CaTM-3 AM could be appl
Externí odkaz:
https://doaj.org/article/49f227754a0847e9a1aabf83551d20ce
Publikováno v:
Plankton & Benthos Research; 2024, Vol. 19 Issue 3, p99-107, 9p
Autor:
Kenjiro Hanaoka, Shimpei Iwaki, Kiyoshi Yagi, Takuya Myochin, Takayuki Ikeno, Hisashi Ohno, Eita Sasaki, Toru Komatsu, Tasuku Ueno, Motokazu Uchigashima, Takayasu Mikuni, Kazuki Tainaka, Shinya Tahara, Satoshi Takeuchi, Tahei Tahara, Masanobu Uchiyama, Tetsuo Nagano, Yasuteru Urano
Publikováno v:
Journal of the American Chemical Society. 144:19778-19790
Fluorogenic probes for bioimaging have become essential tools for life science and medicine, and the key to their development is a precise understanding of the mechanisms available for fluorescence off/on control, such as photoinduced electron transf
Autor:
Takafumi Kasai, Kyohhei Fujita, Toru Komatsu, Tasuku Ueno, Ryosuke Kojima, Kenjiro Hanaoka, Yasuteru Urano
Severely hypoxic environments with oxygen concentrations around 1% are often found in serious diseases such as ischemia and cancer. However, existing near-infrared (NIR) fluorescence probes that can visualize hypoxia are also activated in mildly hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bac85fc3e2c7fce681a2507657d5d220
https://doi.org/10.26434/chemrxiv-2023-k3r73
https://doi.org/10.26434/chemrxiv-2023-k3r73
Autor:
Iwao Tanita, Kunihiko Masaki, Edward Brown Hirohavi, Billy Anthony Diau, Catherine Tsatsia, Henry Stanley Tagua, Sebastian Misiga, Toru Komatsu, Christain Ramofafia
Publikováno v:
Aquatic Conservation: Marine and Freshwater Ecosystems. 32:913-921