Zobrazeno 1 - 10
of 72
pro vyhledávání: '"TORU HANAMURA"'
Autor:
Toru Hanamura, Shigehisa Kitano, Hiroshi Kagamu, Makiko Yamashita, Mayako Terao, Takuho Okamura, Nobue Kumaki, Katsuto Hozumi, Takayuki Iwamoto, Chikako Honda, Sasagu Kurozumi, Naoki Niikura
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background Elucidating the unique immunoregulatory mechanisms in breast cancer microenvironment may help develop new therapeutic strategies. Some studies have suggested that hormone receptors also have immune regulatory functions, but their
Externí odkaz:
https://doaj.org/article/2158c181c20343c3840692b855e95a9a
Autor:
Toru Hanamura, Shigehisa Kitano, Hiroshi Kagamu, Makiko Yamashita, Mayako Terao, Banri Tsuda, Takuho Okamura, Nobue Kumaki, Katsuto Hozumi, Naoki Harada, Takayuki Iwamoto, Chikako Honda, Sasagu Kurozumi, Naoki Niikura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Tumor-infiltrating lymphocytes (TILs) and programmed cell death 1 ligand 1 (PD-L1) are established prognostic and predictive biomarkers for certain breast cancer subsets. However, their association with the immune response complexity is not
Externí odkaz:
https://doaj.org/article/5b61e7baafcc4346bcc32f7c5197e00c
Autor:
Jin Imai, Toru Hanamura, Aya Kawanishi, Takashi Ueda, Yusuke Mishima, Ayano Ito, Yoshihiro Shirataki, Masashi Morimachi, Toshio Kodama, Hirohiko Sato, Motoki Kaneko, Masaya Sano, Erika Teramura, Makiko Monma, Shingo Tsuda, Kota Tsuruya, Hajime Mizukami, Yoshitaka Arase, Mia Fujisawa, Saya Miyahara, Naoya Nakamura, Takayoshi Suzuki, Masashi Matsushima, Hidekazu Suzuki, Shinji Takashimizu, Tatehiro Kagawa, Yasuhiro Nishizaki
Publikováno v:
DEN Open, Vol 3, Iss 1, Pp n/a-n/a (2023)
Abstract Breast cancer is one of the most common malignancies in women worldwide. Although most breast cancers are curable, in cases of metastasis, many are often found in the lungs, bones, liver, and central nervous system; however, metastasis to th
Externí odkaz:
https://doaj.org/article/be815ce77edd44318c924ef21e712301
Autor:
Toru Hanamura, Jessica L. Christenson, Kathleen I. O’Neill, Emmanuel Rosas, Nicole S. Spoelstra, Michelle M. Williams, Jennifer K. Richer
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-15 (2021)
Abstract Purpose Accumulating evidence has attracted attention to the androgen receptor (AR) as a biomarker and therapeutic target in breast cancer. We hypothesized that AR activity within the tumor has clinical implications and investigated whether
Externí odkaz:
https://doaj.org/article/0371be8231394e019312e132cfe5dbce
Autor:
Toru Hanamura, Shigehisa Kitano, Hiroshi Kagamu, Makiko Yamashita, Mayako Terao, Takuho Okamura, Nobue Kumaki, Katsuto Hozumi, Takayuki Iwamoto, Chikako Honda, Sasagu Kurozumi, Naoki Niikura
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/5e68feb6da2e42fe80eb28649b52def6
Autor:
Toru Hanamura, Koichi Ohno, Shinya Hokibara, Hideki Murasawa, Toshitsugu Nakamura, Hidehiko Watanabe, Machiko Kaizuka, Shinji Sawano, Hiroshi Koyama, Ken-ichi Ito
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Recent preclinical data suggest that androgen receptor (AR) signaling plays a significant role in subsets of breast cancer. Clinical trials testing AR-targeting therapies in breast cancer have been conducted. Assessment of AR-sign
Externí odkaz:
https://doaj.org/article/47ba982e08c8434f96402826bed0eee5
Autor:
Toru Higuchi, Megumi Endo, Toru Hanamura, Tatsuyuki Gohno, Toshifumi Niwa, Yuri Yamaguchi, Jun Horiguchi, Shin-Ichi Hayashi
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155844 (2016)
Aromatase inhibitors (AIs) effectively treat hormone receptor-positive postmenopausal breast cancer, but some patients do not respond to treatment or experience recurrence. Mechanisms of AI resistance include ligand-independent activation of the estr
Externí odkaz:
https://doaj.org/article/ac551cbd58c44050a18572da41772afd
Autor:
Toru Hanamura, Shigehisa Kitano, Hiroshi Kagamu, Makiko Yamashita, Mayako Terao, Takuho Okamura, Nobue Kumaki, Katsuto Hozumi, Takayuki Iwamoto, Chikako Honda, Sasagu Kurozumi, Naoki Niikura
Publikováno v:
Cancer Research. 83:P2-20
Purpose: Elucidating the unique immunomodulatory mechanisms in breast cancer microenvironment should provide useful insights to aid the development of new therapeutic strategies for this disease. Some studies suggested the immune regulatory function
Autor:
Emi SATO, Masako SHOMURA, Mari MIZUNO, Kozue YOKOYAMA, Mayako TERAO, Banri TSUDA, Toru HANAMURA, Takuho OKAMURA, Kota FUKAI, Naoki NIIKURA
Publikováno v:
Tokai Journal of Experimental & Clinical Medicine; Apr2024, Vol. 49 Issue 1, p35-42, 8p
Autor:
Jennifer K. Richer, Jason Gertz, Anthony Elias, Britta M. Jacobsen, Rebecca B. Riggins, Steffi Oesterreich, Zheqi Li, Sharon B. Sams, Toru Hanamura, Emmanuel Rosas, Andrew Goodspeed, Kathleen C. Torkko, Jordan Reese, Jessica L. Christenson, Kathleen I. O'Neill, Spencer Arnesen, Nicole S. Spoelstra, Michelle M. Williams
Supplemental Table 1. List of AR regulated genes altered in both D538G and Y537S mutants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9426c2b7d4f19a3639089f895dbc06
https://doi.org/10.1158/0008-5472.22426711
https://doi.org/10.1158/0008-5472.22426711