Zobrazeno 1 - 10
of 101
pro vyhledávání: '"TOMOYUKI NAKAJIMA"'
Autor:
Hisashi Tamada, Takeshi Uehara, Takahiro Yoshizawa, Mai Iwaya, Shiho Asaka, Tomoyuki Nakajima, Masato Kamakura, Hiroyoshi Ota
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-7 (2024)
Abstract Background Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) is a cancer stem cell (CSC) marker of colorectal cancer and may be a CSC marker of other cancer types. Few studies have been conducted on LGR5 expression in extrah
Externí odkaz:
https://doaj.org/article/d0025dad0aa5448b81a650dec4b7fcc4
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background IgG4, which plays a pivotal role in the progression of phenotypically diverse tumors, serves as a prognostic marker because of its influence on cancer immunity. Nevertheless, the functions of IgG4 in tongue squamous cell carcinoma
Externí odkaz:
https://doaj.org/article/f37ed99742e44719a56a9ef63121379e
Autor:
Ryo Kanai, Takeshi Uehara, Takahiro Yoshizawa, Masato Kamakura, Tomoyuki Nakajima, Yasuhiro Kinugawa, Mai Iwaya, Shiho Asaka, Masato Kitazawa, Tadanobu Nagaya, Hiroyoshi Ota
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-6 (2023)
Abstract Background ADP-ribosylation factor-like protein 4 C (ARL4C) is a member of the ARF small GTP-binding protein subfamily. The ARL4C gene is highly expressed in colorectal cancer (CRC). ARL4C protein promotes cell motility, invasion, and prolif
Externí odkaz:
https://doaj.org/article/621662534c324aca98a24906d9ba8f72
Autor:
Takanobu Iwadare, Takefumi Kimura, Naoki Tanaka, Tomoo Yamazaki, Shun-ichi Wakabayashi, Taiki Okumura, Hiroyuki Kobayashi, Yuki Yamashita, Sai P. Pydi, Tomoyuki Nakajima, Mai Iwaya, Ayumi Sugiura, Satoru Joshita, Takeshi Uehara, Takeji Umemura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Among several secreted glycoproteins belonging to the thrombospondin family, thrombospondin 2 (TSP2) is involved in various functions, including collagen/fibrin formation. Liver/serum TSP2 levels have been correlated to liver fibrosis stage
Externí odkaz:
https://doaj.org/article/cbb74aa4f06742c78b5d032babd3d074
Autor:
Yoh-ichiro Iwasa, Tomoyuki Nakajima, Kentaro Hori, Yoh Yokota, Ryosuke Kitoh, Takeshi Uehara, Yutaka Takumi
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1685 (2023)
Although anti-programmed death-1 (PD-1) antibody therapy improves the prognosis in patients with head and neck squamous cell carcinoma (HNSCC), some patients exhibit disease progression even after showing a good response to the treatment initially be
Externí odkaz:
https://doaj.org/article/e60c9b81d9fe4dc89f92168be18dd35c
Autor:
Masato Kamakura, Takeshi Uehara, Mai Iwaya, Shiho Asaka, Shota Kobayashi, Tomoyuki Nakajima, Yasuhiro Kinugawa, Tadanobu Nagaya, Takahiro Yoshizawa, Akira Shimizu, Hiroyoshi Ota, Takeji Umemura
Publikováno v:
Diagnostic Pathology, Vol 17, Iss 1, Pp 1-7 (2022)
Abstract Background Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a strong cancer stem cell marker in colorectal cancer; however, there are many unclear aspects of LGR5 expression in pancreatic cancer. It has been reported tha
Externí odkaz:
https://doaj.org/article/d156d96186e542e29b6397a8bca7b16b
Autor:
Yasuhiro Kuraishi, Takeshi Uehara, Takashi Muraki, Mai Iwaya, Yasuhiro Kinugawa, Tomoyuki Nakajima, Takayuki Watanabe, Yusuke Miyagawa, Takeji Umemura
Publikováno v:
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-8 (2021)
Abstract Background Pancreaticobiliary maljunction (PBM) is a condition characterized by chronic inflammation due to refluxed pancreatic juice into the biliary tract that is associated with an elevated risk of biliary tract cancer. DNA double-strand
Externí odkaz:
https://doaj.org/article/f0391a7f88f04a249e5c8cffe5933bd8
Autor:
Yasuhiro Kinugawa, Takeshi Uehara, Mai Iwaya, Shiho Asaka, Shota Kobayashi, Tomoyuki Nakajima, Masamichi Komatsu, Masanori Yasuo, Hiroshi Yamamoto, Hiroyoshi Ota
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background It is difficult to distinguish between multicentric Castleman’s disease (MCD) and IgG4-related lung disease (IgG4-LD), an IgG4-related disease (IgG4-RD) in the lung. Methods We focused on IL-6, which is elevated in MCD, to disti
Externí odkaz:
https://doaj.org/article/3214bf31dc0f415c8a1a615216f641b3
Autor:
Takehito Ehara, Takeshi Uehara, Tomoyuki Nakajima, Yasuhiro Kinugawa, Shota Kobayashi, Mai Iwaya, Hiroyoshi Ota, Yuji Soejima
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is an important cancer stem cell marker in gastric cancer. However, no detailed studies are available on LGR5 expression in poorly differentiated gastric adenocarc
Externí odkaz:
https://doaj.org/article/085c88dd79dc4378a4e7f9162d666217
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5), a component of the Wnt receptor complex, is thought to lineage label gastric and intestinal stem cells. LGR5 expression is increased in colorectal carcinoma (CRC)
Externí odkaz:
https://doaj.org/article/85649cc371f04cbb92dbfe2bf2d59191