Zobrazeno 1 - 10
of 27
pro vyhledávání: '"TOMOKO TAKAMARU"'
Autor:
Hiroshi Onishi, Chihiro Udagawa, Michiaki Kubo, Seigo Nakamura, Sadako Akashi-Tanaka, Takashi Kuwayama, Chie Watanabe, Tomoko Takamaru, Hiroyuki Takei, Takashi Ishikawa, Kana Miyahara, Hiroshi Matsumoto, Yoshie Hasegawa, Yukihide Momozawa, Siew-Kee Low, Goro Kutomi, Hiroaki Shima, Fukino Satomi, Minoru Okazaki, Hisamitsu Zaha, Mai Onomura, Ayami Matsukata, Yasuaki Sagara, Shinichi Baba, Akimitsu Yamada, Kazuhiro Shimada, Daisuke Shimizu, Koichiro Tsugawa, Arata Shimo, Mikael Hartman, Ching-Wan Chan, Soo Chin Lee, Itaru Endo, Hitoshi Zembutsu
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201606 (2018)
PURPOSE:Although association studies of genetic variations with the clinical outcomes of breast cancer patients treated with tamoxifen have been reported, genetic factors which could determine individual response to tamoxifen are not fully clarified.
Externí odkaz:
https://doaj.org/article/df5059f5fb414b94b9b44bce028966f3
Autor:
Yusuke Nakamura, Soo Chin Lee, Ching-Wan Chan, Mikael Hartman, Ern Yu Tan, Arata Shimo, Koichiro Tsugawa, Daisuke Shimizu, Kazuhiro Shimada, Akimitsu Yamada, Shinichi Baba, Yasuaki Sagara, Ayami Matsukata, Mai Onomura, Hisamitsu Zaha, Minoru Okazaki, Fukino Satomi, Hiroaki Shima, Goro Kutomi, Yoshie Hasegawa, Hiroshi Matsumoto, Kana Miyahara, Takashi Ishikawa, Hiroyuki Takei, Tomoko Takamaru, Chie Watanabe, Takashi Kuwayama, Sadako Akashi-Tanaka, Seigo Nakamura, Hitoshi Zembutsu
Supplementary Figure S1. 　ER status in breast cancer tissues was associated with Ki-67 response after tamoxifen therapy. (A) Ki-67 response was lower in the tissues in which the proportion of ER-positive cells was less than 2/3 than in the tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36cda7d9e05983c54069e73f82173ebc
https://doi.org/10.1158/1078-0432.22465632
https://doi.org/10.1158/1078-0432.22465632
Autor:
Yusuke Nakamura, Soo Chin Lee, Ching-Wan Chan, Mikael Hartman, Ern Yu Tan, Arata Shimo, Koichiro Tsugawa, Daisuke Shimizu, Kazuhiro Shimada, Akimitsu Yamada, Shinichi Baba, Yasuaki Sagara, Ayami Matsukata, Mai Onomura, Hisamitsu Zaha, Minoru Okazaki, Fukino Satomi, Hiroaki Shima, Goro Kutomi, Yoshie Hasegawa, Hiroshi Matsumoto, Kana Miyahara, Takashi Ishikawa, Hiroyuki Takei, Tomoko Takamaru, Chie Watanabe, Takashi Kuwayama, Sadako Akashi-Tanaka, Seigo Nakamura, Hitoshi Zembutsu
Supplementary Table S1 Association between all CYP2D6 genotype and ER status in pre-treatment tissue.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbeb03daafb0aa3d97beff4ff255f1c
https://doi.org/10.1158/1078-0432.22465629
https://doi.org/10.1158/1078-0432.22465629
Autor:
Yusuke Nakamura, Soo Chin Lee, Ching-Wan Chan, Mikael Hartman, Ern Yu Tan, Arata Shimo, Koichiro Tsugawa, Daisuke Shimizu, Kazuhiro Shimada, Akimitsu Yamada, Shinichi Baba, Yasuaki Sagara, Ayami Matsukata, Mai Onomura, Hisamitsu Zaha, Minoru Okazaki, Fukino Satomi, Hiroaki Shima, Goro Kutomi, Yoshie Hasegawa, Hiroshi Matsumoto, Kana Miyahara, Takashi Ishikawa, Hiroyuki Takei, Tomoko Takamaru, Chie Watanabe, Takashi Kuwayama, Sadako Akashi-Tanaka, Seigo Nakamura, Hitoshi Zembutsu
Purpose: CYP2D6 is the key enzyme responsible for the generation of the potent active metabolite of tamoxifen, “endoxifen.” There are still controversial reports questioning the association between CYP2D6 genotype and tamoxifen efficacy. Hence, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ce89ce8de2a1c253ff6b551d8c5a9d
https://doi.org/10.1158/1078-0432.c.6526092
https://doi.org/10.1158/1078-0432.c.6526092
Autor:
Rikako Hashimoto, Sadako Akashi-Tanaka, Chie Watanabe, Hiroko Masuda, Kanae Taruno, Tomoko Takamaru, Yoshimi Ide, Takashi Kuwayama, Yasuhiro Kobayashi, Masafumi Takimoto, Seigo Nakamura
Publikováno v:
Breast cancer (Tokyo, Japan). 29(6)
Background Dedicated breast positron emission tomography (dbPET) has been developed for detecting smaller breast cancer. We investigated the diagnostic performance of dbPET in patients with known breast cancer. Methods Eighty-two preoperative patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d076d56eed4bd3598cdcff69ec7f809b
https://pubmed.ncbi.nlm.nih.gov/35768684
https://pubmed.ncbi.nlm.nih.gov/35768684
Autor:
Shinichi Baba, Takashi Kuwayama, Yusuke Nakamura, Hitoshi Zembutsu, Minoru Okazaki, Goro Kutomi, Fukino Satomi, Seigo Nakamura, Mikael Hartman, Kazuhiro Shimada, Sadako Akashi-Tanaka, Chie Watanabe, Tomoko Takamaru, Mai Onomura, Hiroshi Matsumoto, Arata Shimo, Kana Miyahara, Yasuaki Sagara, Hiroyuki Takei, Hiroaki Shima, Daisuke Shimizu, Soo Chin Lee, Ching Wan Chan, Hisamitsu Zaha, Akimitsu Yamada, Takashi Ishikawa, Ayami Matsukata, Yoshie Hasegawa, Ern Yu Tan, Koichiro Tsugawa
Publikováno v:
Clinical Cancer Research. 23:2019-2026
Purpose: CYP2D6 is the key enzyme responsible for the generation of the potent active metabolite of tamoxifen, “endoxifen.” There are still controversial reports questioning the association between CYP2D6 genotype and tamoxifen efficacy. Hence, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c2a35b1a2193917bbd6a320ea1996e8
https://doi.org/10.1158/1078-0432.ccr-16-1779
https://doi.org/10.1158/1078-0432.ccr-16-1779
Autor:
TOMOKO TAKAMARU1, GORO KUTOMI1, FUKINO SATOMI1, HIROAKI SHIMA1, KEISUKE OHNO1, HIDEKAZU KAMESHIMA1, YASUYO SUZUKI1, TOUSEI OHMURA1, HIROYUKI TAKAMARU2, MASANORI NOJIMA3, MITSURU MORI3, KOICHI HIRATA1 fujikane@sapmed.ac.jp
Publikováno v:
Experimental & Therapeutic Medicine. 2014, Vol. 7 Issue 2, p456-460. 5p.
Autor:
Hiroaki Shima, Masamitsu Hatakenaka, Koichi Hirata, Tosei Omura, Fukino Satomi, Hidekazu Kameshima, Goro Kutomi, Hideki Maeda, Mitsuru Mori, Tadashi Hasegawa, Tomoko Takamaru
Publikováno v:
Experimental and Therapeutic Medicine
In breast cancer, single-photon emission computed tomography/computed tomography (SPECT/CT) shows the exact anatomical location of sentinel nodes (SN). SPECT/CT mainly exposes axilla and partly exposes atypical sites of extra-axillary lymphatic drain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f54fe576fba695dd03f607f772dd88
http://europepmc.org/articles/PMC4186387
http://europepmc.org/articles/PMC4186387
Autor:
Hiroaki Shima, Hitoshi Zembutsu, Tomoko Takamaru, Yasuyo Suzuki, Tousei Ohmura, Mitsuru Mori, Fukino Satomi, Goro Kutomi, Koichi Hirata, Seiko Otokozawa
Publikováno v:
Experimental and Therapeutic Medicine
The aim of the present study was to evaluate whether preoperative computed tomography (CT) is a useful modality for the diagnosis of axillary lymph node metastasis. The axillary lymph node status was examined in patients with primary breast cancer wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0bf632057f62d73000f44725f65e428
https://doi.org/10.3892/etm.2014.1787
https://doi.org/10.3892/etm.2014.1787
Autor:
Hiroaki Shima, Mitsuru Mori, Koichi Hirata, Tousei Ohmura, Fukino Satomi, Goro Kutomi, Yasuyo Suzuki, Hiroyuki Takamaru, Tomoko Takamaru, Keisuke Ohno, Masanori Nojima, Hidekazu Kameshima
Publikováno v:
Experimental and Therapeutic Medicine
For sentinel lymph node biopsy (SLNB), a combination of dye-guided and γ-probe-guided methods is the most commonly used technique. However, the number of institutes in which the γ-probe-guided method is able to be performed is limited, since specia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79276a0fdbf29a33865dd769f51fdbd2
https://doi.org/10.3892/etm.2013.1445
https://doi.org/10.3892/etm.2013.1445