Zobrazeno 1 - 10
of 137
pro vyhledávání: '"TOB1"'
Autor:
Hongjie He, Kexian Dong, Mingming Chen, Yuanyuan Wang, Yawen Li, Dong Wang, Mansha Jia, Xiangning Meng, Wenjing Sun, Songbin Fu, Jingcui Yu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Gastric cancer is one of the most malignant digestive tract tumors worldwide and its progression is associated with gene expression and metabolic alteration. We revealed that the gastric cancer patients with lower expression level of TOB1 ex
Externí odkaz:
https://doaj.org/article/ff0a2496c6b147ca82ec3f9e13a5b941
Autor:
Jinfeng Zhang, Yunlong Li, Jing Chen, Tongtong Huang, Jing Lin, Yilin Pi, Huiting Hao, Dong Wang, Xiao Liang, Songbin Fu, Jingcui Yu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe ErbB-2.1(TOB1) signaling transducer protein is a tumor-suppressive protein that actively suppresses the malignant phenotype of gastric cancer cells. Yet, TOB1 negatively regulates the activation and growth of different immune cells. U
Externí odkaz:
https://doaj.org/article/edec4b7adc8c4843b67f0edcbd1c0bb8
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Background Ankylosing spondylitis (AS) is a chronic inflammatory arthritis. Upregulation of microRNA (miR)-92b-3p is associated with enhanced osteoblastic differentiation. The current study sought to investigate the functional mechanism of m
Externí odkaz:
https://doaj.org/article/6703c54c229946bdb45e1017c1c15779
Publikováno v:
Exploration of Medicine, Vol 3, Iss 5, Pp 468-478 (2022)
Inflammatory bowel disease (IBD) is a multifactorial chronic disease. Patients with IBD have an increased risk of developing colorectal cancer which has become a major health concern. IBD might exert a role of engrams for making the condition of spec
Externí odkaz:
https://doaj.org/article/3777ebf49a7b4daab5425f7f27ad281d
Autor:
Ritian Lin, Caiyun Ma, Leilei Fang, Chunjin Xu, Cui Zhang, Xiaohan Wu, Wei Wu, Ruixin Zhu, Yingzi Cong, Zhanju Liu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 4, Pp 1201-1221 (2022)
Background & Aims: TOB1 is an anti-proliferative protein of Tob/BTG family and typically involved in the tumorigenesis and T cell activation. Although TOB1 is associated with T helper 17 cell–related autoimmunity, its role in modulating T cell–me
Externí odkaz:
https://doaj.org/article/e51c608249b1448ab4029f2c53668b9c
Akademický článek
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Publikováno v:
Cancer Medicine, Vol 9, Iss 4, Pp 1503-1514 (2020)
Abstract TOB1 participates in various kinds of cancers. However, its role in pancreatic cancer has rarely been reported. In this study, we explored the expression and mechanisms of TOB1 in regulating the malignant phenotype of pancreatic cancer cells
Externí odkaz:
https://doaj.org/article/fbe1448b7d784925a2b8742f90618471
Autor:
Dong Wang, Yunlong Li, Shuning Sui, Mengdi Cai, Kexian Dong, Ping Wang, Xiao Liang, Songbin Fu, Jingcui Yu
Publikováno v:
PeerJ, Vol 10, p e12904 (2022)
Background We previously identified the tumor suppressor gene TOB1 as related to gastric cancer. The purpose of this study was to explore whether TOB1 induces autophagy through the AKT/mTOR signaling pathway in gastric cancer. Methods Western blottin
Externí odkaz:
https://doaj.org/article/5331a0d7b63449aeb4d211f0677b04b5
Akademický článek
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Akademický článek
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